A5038450024- Spine and Intervertebral Disc Pathology
- Musculoskeletal pain and rehabilitation
- Scoliosis diagnosis and treatment
- Spinal Fractures and Fixation Techniques
- Cervical and Thoracic Myelopathy
- Nutrition and Health in Aging
- Pain Mechanisms and Treatments
- Management of metastatic bone disease
- Bone health and osteoporosis research
- Advanced Neuroimaging Techniques and Applications
- Pelvic and Acetabular Injuries
- Hip and Femur Fractures
- Advanced Glycation End Products research
- Spinal Hematomas and Complications
- Peripheral Nerve Disorders
- Anesthesia and Pain Management
- Body Composition Measurement Techniques
- Bone health and treatments
- Pregnancy-related medical research
- Botulinum Toxin and Related Neurological Disorders
- Balance, Gait, and Falls Prevention
- Cardiovascular, Neuropeptides, and Oxidative Stress Research
- Orthopaedic implants and arthroplasty
- Oral and Maxillofacial Pathology
- Bone and Joint Diseases
Chiba University
2011-2024
Chiba University Hospital
2018-2024
Asahi General Hospital
2023
Teikyo University Chiba Medical Center
2022
University of Tsukuba
2021
Study Design Cross-sectional observational study. Purpose To compare measurements of appendicular skeletal muscle mass (ASMM) and whole fat (WFM) obtained using dualenergy X-ray absorptiometry (DXA) bioelectrical impedance analysis (BIA) among patients with low back pain (LBP). Moreover, the study investigated correlation between BIA-based ASMM DXA-based bone mineral density (BMD). Overview Literature If reliable, BIA may be a useful alternative to DXA as screening tool for sarcopenia...
The aim of this study was to determine whether advanced glycation end products (AGEs) revealed by skin autofluorescence (SAF), serum and urine pentosidine level, homocysteine level can serve as a biomarker for sarcopenia in older women. participants were 70 elderly AGEs pentosidine, homocysteine, SAF measured aging markers. This shows that among the biomarkers aging, correlates with loss appendicular lean mass sarcopenia. Moreover, values exhibited positive correlation age correlated each...
Abstract This study aimed to perform a comparative analysis of postoperative results between lumbar degenerative spondylolisthesis (LDS) treated with oblique lateral interbody fusion (OLIF) and transforaminal (TLIF) from the Chiba spine surgery registry database. Sixty-five patients who underwent single-level OLIF (O group) for LDS ≥ 3 years’ follow-up were retrospectively reviewed. The control group comprised 78 TLIF (T group). analyzed variables included global alignment, radiological...
Controlled laboratory study.This study aimed to evaluate the in vitro pharmacological activity of growth factors (GFs) freeze-dried platelet-rich plasma (FD-PRP) after storage for 4 weeks.Freshly prepared PRP is a rich source many GFs. We reported that FD-PRP stored 8 weeks accelerated bone union rat posterolateral fusion model equally well as fresh-PRP. However, longterm has not been shown vitro.Immediately preparation, storage, platelet count was measured. Human osteoblasts were treated...
Condoliase is a newly approved drug that improves symptoms associated with lumbar disk herniation (LDH) by intradiscal administration. This study aimed to evaluate the mid-term outcomes of condoliase injection, examine adverse events, including cases required surgery after administration, and verify in which could be effective.We enrolled patients LDH who were treated conservatively for at least six weeks received condoliase. We assessed visual analog scale (VAS) score, Japanese Orthopaedic...
Oblique lumbar interbody fusion surgery is a recently introduced minimally invasive lateral for degenerative disease. There have been no reports of associated ureteral injury. A 77-year-old Japanese woman underwent oblique spondylolisthesis with refractory low back pain and in both legs. The patient experienced abdominal 2 days after surgery. Delayed contrast-enhanced computed tomography retrograde urography revealed leakage contrasted urine from the ureter into retroperitoneal space,...
Retrospective observational study.We considered the relationship between spinal alignment and skeletal muscle mass on clinical outcomes following a surgery for lumbar stenosis (LSS).There are no reports of preoperative factors predicting residual low back pain LSS.Our target population included 34 women (mean age, 74.4 years) who underwent LSS. Prior to 6 months after surgery, systemic bone mineral density lean soft tissue were measured using dual-energy X-ray absorptiometry. Skeletal index...
Abstract Background Lumbar spinal disease causes disabilities in performing daily activities. Operative treatments are aimed at pain relief and rapid return to routine activity. Patient-based outcome measures used evaluate pathologies therapeutic effects associated with lumbar disease. Nevertheless, it remains unknown as how much such treatment improves activity levels. The purpose of the current study was measure changes levels before after surgery using a wearable tracker analyze...
Study Design. An in vivo model to study the effect of an injectable hyaluronic acid (HA) hydrogel following puncture-induced lumbar disc injury rabbits. Objectives. The aim this was determine efficacy HA maintain height and tissue hydration, promote structural repair, attenuate inflammation innervation discs. Summary Background Data. Previously, we have demonstrated that alleviated inflammation, innervation, pain repair. Nevertheless, a weight-bearing animal not performed. Methods. We...
Introduction: Failed spinal fusion surgery sometimes requires salvage when symptomatic, especially with postsurgical decrease in intervertebral disc height followed by foraminal stenosis. For such cases, an anterior approach to lumbar lateral interbody (LLIF) provides safe, direct access the pathological space and a potential improvement rate. One LLIF approach, oblique (OLIF), targets window of discs achieve successful fusion. The current technical note describes revision using OLIF procedure.
Limb muscle mass measurement using dual-energy X-ray absorptiometry (DXA) is considered the gold standard for diagnosis of sarcopenia. Moreover, bioelectrical impedance analysis (BIA) also recognized as a beneficial tool considering its high correlation with DXA. However, it remains to be elucidated whether DXA and BIA can accurately measure trunk lean mass. The aim this study was investigate between measurements cross-sectional area (CSA) muscles measured magnetic resonance imaging (MRI)...
Study Design. A basic study using a rodent model of sarcopenia. Objective. To elucidate the contribution oxidative stress to muscle degeneration and efficacy antioxidant treatment for sarcopenia an animal neurogenic Summary Background Data. Oxidative has been reported be involved in number pathologies, including musculoskeletal disorders. Its relationship with sarcopenia, one potential origins lower back pain, however, is not yet fully understood. Methods. Myoblast cell lines (C2C12) were...
Immunohistological analysis of dichotomizing sensory nerve fibers projecting to the lumbar multifidus muscles and intervertebral disc (IVD), facet joint (FJ), or sacroiliac (SIJ) in rats.To elucidate IVDs, FJs, SIJs.Clinically, origin low back pain remains unknown. Multiple studies have identified muscles, SIJs as sources pain. Pain may originate directly from be referred spine, both. Dorsal root ganglion (DRG) neurons with axons been reported several species are thought related pain.We used...
Wearable accelerometers can be used to evaluate waking and sleeping movements. Although a correlation between accelerometer data captured at the wrist waist has been reported, it not evaluated in patients with low back pain. Therefore, this study aimed correlations movement measured waist, using wearable accelerometers, pain.Twenty chronic pain 20 healthy volunteers were enrolled. Two identical simultaneously worn by each participant, one on nondominant other for 1 week. We compared mean...
Objective To validate the relationship between residual walking ability and monthly care cost as well long-term insurance (LTCI) certification level in elderly patients after surgical treatment for hip fractures Japan. Methods Elderly aged >75 years who underwent our hospital were included. The preand post-surgical (6-month) LTCI presence or absence of dementia was determined from medical records questionnaires. Walking classified into 6 levels used daily practice. Based on these data, we...
To investigate the risk of epidural hematoma after spinous process-splitting laminectomy (SPSL).A total 137 cases (mean age, 72.4 years; 68 men) SPSL were included. Of these, there instances (3.7%; mean 70.5 all male) postoperative development new neurologic deficit due to requiring reoperation. The 133 subjects (72.5 64 with normal course used as controls, and comparisons made between both groups using chi-squared Student's t-tests. Regarding our investigation factors for hematoma, logistic...
Giant cell tumor is known to be a benign neoplasm that arises most commonly in the long bones, while cases spine are rare. Recently, denosumab, monoclonal antibody inhibits receptor activator of nuclear factor-kappa β ligand, has been used treat patients with giant tumor. However, there few reports total en bloc spondylectomy being for paravertebral lesions following denosumab therapy. Our patient was 20-year-old Japanese woman 4-month history lower back pain. A spinal computed tomography...
Study Design. A retrospective study. Objective. The aim of this study was to determine the publication rate and impact factors (IFs) among all abstracts presented at 2010 2012 meetings International Society for Lumbar Spine (ISSLS). Summary Background Data. overseas reported be around 50%. However, IFs oral poster presentations made ISSLS were unclear. Moreover, whether rates differed papers associated with or unknown. Methods. We investigated 1,126 (oral, special posters, general posters)...
The purpose of this study was to determine the relationship between vertebral bodies, psoas major morphology, and course lumbar nerve tracts using diffusion tensor imaging (DTI) before lateral interbody fusion (LIF) treat spinal deformities.