Diabetic foot ulcers (DFU) may cause significant morbidity and lower extremity amputation (LEA) due to diabetic problems can occur more often compared the general population. The purpose of present study was use an epidemiological design determine quantify risk factors subsequent in hospitalized DFU patients.We performed a hospital-based, case-control 47 patients with LEA control without LEA. subjects were matched cases respect age (±5 years), sex, nutritional status, ratio 1:1. This...

Background: This study attempted to determine the disease burden in terms of clinical profile and outcome diabetic foot ulcer (DFU) admissions at a tertiary care hospital developing country.Methods: In this descriptive study, data were collected from medical record patients with who treated Dr. Kariadi General Hospital during 3-year period. The demographic characteristic, type lesion, etiology, isolated microorganism, treatment, reviewed.Results: Foot problems accounted for 16.2% total...

BACKGROUND Indonesia was a part of the most recent edition DiabCare Asia held in 2008. 2012 is modeled after similar project to provide latest information facilitate healthcare policymaking this area.METHODS This an observational, non-interventional, cross-sectional study patients with type 2 diabetes mellitus from primary, secondary, and tertiary care centers Indonesia. Patient data collected included demography, medical history complications, eye foot examinations, management, laboratory...

Background : Diabetic foot is one of the chronic complications diabetes mellitus and are most feared by people who suffer as it can lead to disability or even death. This more specific research on risk factors ethnic communities Minangkabau society. The purpose this prove related incidence diabetic in with type 2 mellitus. Methods applied mix method were quantitative main approach (case control design) qualitative support (indepth interview). Target population all a diagnosis Padang City,...

Pendahuluan
 Jawa Tengah merupakan propinsi dengan kasus COVID-19 terbanyak ke-4 di Indonesia (lebih dari 8.000 kasus). RS Umum Pusat Dr. Kariadi (RSDK) sebagai rujukan memiliki 436 terkonfirmasi per 10 Juli 2020. Diabetes mellitus (DM) diketahui menurunkan sistem imun dan memperburuk reaksi inflamasi. Karakteristik keluaran pasien DM RSDK belum pernah dilaporkan sebelumnya.
 Metode
 Data rekam medis RSDK. Diagnosis DM: riwayat dan/atau GDS >200 mg/dL atau HbA1c >7%....

Maturity level of dendritic cells (DC) plays a pivotal role in initiating and regulating autoimmunity. In graves’ disease (GD), DCs have more active immune responses than those healthy subjects. Our previous study demonstrated immunoregulatory effects vitro 1,25-D3 on maturation DC GD patients. This aims to evaluate the effect oral 1α-D3 Methods: Twenty five patients with thyrotoxicosis were divided into two groups: 12 receiving 13 placebo, addition treatment propylthiouracil. Comparison...

BACKGROUND: Metabolic syndrome (MetS), which is characterized by insulin resistance, adipocyte accumulation, and obesity, has been linked to malignancy development. Both leptin, an adipose tissue-produced cytokine-like hormone, adiponectin, a hormone secreted tissue, play roles in the progression of MetS. However, presence leptin adiponectin also assumed be associated with cancer proliferation. Therefore, it necessary investigate profile levels MetS patients non-malignancy.METHODS: This was...

Diabetes Mellitus (DM) has reached a number of 382 million in 2013 and expected to rise 592 by 2035.Chronic diabetes can lead impaired formation erythropoietin haemoglobin production may cause anemia.Inhibition aldose reductase is key point treatment prevention complications diabetes.Colocasia esculenta (CE) leaf one Indonesian vegetables which inhibition effect on activity.This research was true experimental study with post-test only group design.21 male Sprague dawley rats were divided...

Background: Obesity has become a major global health issue which leads to various complications, including hepatic diseases. However, we found rare case of morbid obesity and symptomatic multiple liver cysts. Aim: This article aims represent cysts surgically managed by sleeve gastrectomy cyst unroofing were performed in single surgery. Case report: 41-year-old female presented with blunt intermittent abdominal pain the right upper quadrant. Stage II hypertension, tenderness on quadrant...

Background: Sarcopenia is a degenerative condition closely associated with the elderly, especially those metabolic syndrome. Patients sarcopenia often experience decrease in muscle mass which replaced by fat mass. Dyslipidemia through insulin resistance mechanisms can cause dysfunction elderly. Additionally, low albumin levels mass, worsening sarcopenia. Uric acid also influence development of sufferers tend to an increase TNF-α due resistance. The incidence syndrome increased morbidity and...

Background: Non-Alcoholic Fatty Liver Disease (NAFLD) is common liver disease often found and occurs in community. Prevalence of has risen rapidly along with an increase obesity incidence women. Inflammation condition obese causing IL-6, Platelets Count (PLTC), Aldosterone level increased risk developing NAFLD. Aim: To analyze differences PLTC, between Obese Non-Obese Women. Methods: This study was observational cross-sectional analytical that conduct NovemberJanuari 2021 at Diponegoro...

Graves' disease (GD) is characterized by thyroid overactivity. Anti-thyroid drugs (ATDs), such as propylthiouracil (PTU) and methimazole (MMI), are commonly used for GD treatment, studies have suggested a link between these elevated lipoprotein levels. However, data on their effects lipoproteins, insulin resistance, or low-density receptor (LDL-R) levels lacking, both in Indonesia other countries. This study investigated changes LDL-R, resistance markers with ATD treatment.

Obese condition which causes changes in body composition affect to very serious consequences on Bone Mineral Density (BMD). This study aims analyze correlation between that consist of lean mass, fat and visceral rating with Density. Cross-sectional conducted from June-December 2023 at Diponegoro National Hospital (RSND) Semarang. Body respondent was measured using Tanita Analyzer bone mineral density analyzed Dual X-ray absorptiometry (DXA) Semarang Medical Center. Statistical Analysis for...

Background: Obese is risk factor for abnormal glucose homeostasis and causes oxidative stress that can decrease insulin sensitivity resulting in hyperglycemia hyperinsulinemia. Black soy bean contains anthocyanins isoflavones, it expected to reduce stress. Objective: Determine the effect of various dosage black soybean extract (Glycine soja.) on blood glucose, levels, HOMA - IR obese Sprague Dawley (SD) rats.Methods: True experimental study with randomized controlled pre test-post test...

Background: The prevalence of hypertension in type 2 diabetic patients is 1,5-3 times higher than it nondiabetic individuals This chronic condition accelerates macrovascular complications. Research about risk factors still rare because its causes multifactorial. objectives this research to explain the affecting patients.Methods: An observational studies with case-control study design Primary Healthcare Centers Pati District. Patients diabetes are case, while without control. There were 57...

Background: The prevalence of hypertension in type 2 diabetic patients is 1,5-3 times higher than it nondiabetic individuals This chronic condition accelerates macrovascular complications. Research about risk factors still rare because its causes multifactorial. objectives this research to explain the affecting patients.Methods: An observational studies with case-control study design Primary Healthcare Centers Pati District. Patients diabetes are case, while without control. There were 57...

ABSTRACTObjective: The autoimmune reaction in Graves’ disease (GD) is induced by self-antigen, which presented dendritic cells (DCs). DCs GD have more active immune responses than those healthy subjects. ability of DC as antigen-presenting cell determined its maturity level. InGD, vitamin D level inversely proportional to antibody titer and proportionally associated with remission status. Studies on subjects andautoimmune patients (systemic lupus erythematosus (SLE), multiple sclerosis (MS),...

Background : Stroke is the second leading cause of death and a major long term disability. The prevalence stroke in type 2 diabetes mellitus patients were increased. Diabetic have 3-4 times greater risk for ischemic than non-diabetic. Information regarding factors with still limited. This study propose to determine patients. Methods Observational-analytic case-control design qualitative data. Two groups include this study, 48 patient s without Kariadi hospital, used by consecutive sampling....