A5100650695- Cancer-related molecular mechanisms research
- MicroRNA in disease regulation
- RNA modifications and cancer
- Gout, Hyperuricemia, Uric Acid
- Synthesis and Biological Activity
- Ferroptosis and cancer prognosis
- Inflammasome and immune disorders
- Ubiquitin and proteasome pathways
- Multiple Myeloma Research and Treatments
- Cancer-related gene regulation
- Circular RNAs in diseases
- Cancer therapeutics and mechanisms
Shanghai Jiao Tong University
2020
Shanghai First People's Hospital
2019-2020
Ruijin Hospital
2019
Zero to Three
2019
Harbin Medical University
2018
University of Miami
2016
Centro de Investigación del Cáncer
2008
Universidad de Salamanca
2008
Abstract Diabetes cardiomyopathy (DCM) is a critical complication of long-term chronic diabetes mellitus and characterized by myocardial fibrosis hypertrophy. It has been suggested that DCM related to pyroptosis, programmed cell death associated with inflammation. The long non-coding RNA Kcnq1ot1 involved in different pathophysiological mechanisms multiple diseases, including acute damage arrhythmia. Our previous study found was elevated left ventricular tissue diabetic mice. However,...
Abstract MicroRNAs are beneficial for cancer therapy as they can simultaneously downregulate multiple targets involved in diverse biological pathways related to tumor development. In papillary thyroid cancer, many microRNAs were identified differentially expressed factors tissues. another way, recent studies revealed cell proliferation, cycling, apoptosis, and autophagy critical controlling development progression. As miR‐524‐5p was approved a suppressor targeting genes several types of...
This study aims at probing into the expression and biological function of long non-coding RNA (lncRNA) TMPO-AS1 in non-small cell lung cancer (NSCLC), exploring its regulatory role for miR-204-3p erb-b2 receptor tyrosine kinase 2 (ERBB2).In this study, paired NSCLC samples were collected, levels TMPO-AS1, ERBB2 examined by quantitative real-time polymerase chain reaction (qRT-PCR); proliferative ability colony formation detected CCK-8 assay plate assay, respectively; flow cytometry was...
Abstract Lung cancer is the leading cause of deaths and yet genes that drive this malignancy are not entirely known. MicroRNA (miRNA) important regulators gene expression aberrant miRNA has been linked to lung oncogenesis; however, little known about their contribution in tumor initiation. We’ve determined miR-31 overexpressed human adenocarcinoma overexpression independently correlates with decreased patient survival. promotes cell proliferation growth vivo. We also developed a transgenic...