- Cholangiocarcinoma and Gallbladder Cancer Studies
- Ultrasound and Hyperthermia Applications
- Mast cells and histamine
- Cardiac Arrhythmias and Treatments
- Ferroptosis and cancer prognosis
- Biological and pharmacological studies of plants
- Nanoplatforms for cancer theranostics
- Neonatal Respiratory Health Research
- Cardiac Ischemia and Reperfusion
- Gallbladder and Bile Duct Disorders
- Cardiovascular Function and Risk Factors
- Renin-Angiotensin System Studies
- Hepatocellular Carcinoma Treatment and Prognosis
- Cardiovascular Disease and Adiposity
- Congenital Anomalies and Fetal Surgery
- Sarcoma Diagnosis and Treatment
- Bladder and Urothelial Cancer Treatments
- Congenital Diaphragmatic Hernia Studies
- Medical Research and Treatments
- Nanoparticle-Based Drug Delivery
- Peptidase Inhibition and Analysis
- Hepatitis C virus research
- Cardiac Fibrosis and Remodeling
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Neuroendocrine Tumor Research Advances
Binzhou University
2022-2025
Binzhou Medical University
2022-2025
Zhengzhou University
2015-2019
Henan Provincial People's Hospital
2015-2019
Nanfang Hospital
2012-2018
Southern Medical University
2012-2018
With the rapid development of cancer-targeted nanotechnology, a variety nanoparticle-based drug delivery systems have clinically been employed in cancer therapy. However, multidrug resistance significantly impacts therapeutic efficacy. Physical non-drug therapy has emerged as new and promising strategy. This study aimed to determine whether novel folate-nanobubbles (F-NBs), combined with ultrasound (US), could act safe effective physical targeted Using folate-conjugated N-palmitoyl chitosan...
Primary hepatic carcinosarcoma (HCS) is an extremely rare malignant tumor with carcinomatous and sarcomatous elements. Few reported cases of HCS exist, especially sufficient records to describe imaging pathological features, making the diagnosis, treatment, prognosis a significant challenge for physicians. Here, we report case spontaneous rupture as initial symptom in 77-year-old elderly male who was admitted right upper abdominal pain 8 days. The computed tomography enhancement scan...
Low-intensity ultrasound-microbubble (LIUS-MB) treatment is a promising antivascular therapy for tumors. We sought to determine whether LIUS-MB with an appropriate ultrasound pressure could achieve substantial and persistent cessation of tumor perfusion without having significant effects on normal tissue. Further, we investigated the mechanisms underlying this treatment. Murine S-180 sarcomas, thigh muscles, skin tissue from 60 tumor-bearing mice were subjected sham therapy, application...
Abstract The patients suffering from myocardial infarction (MI) undergo cardiac remodeling with the features of expanded infarct size and dilated left ventricle. Multiple microRNAs (miRNAs) are emerged as crucial modulators to participate in process. This study is mainly intended clarify regulatory mechanism miR‐132 MI‐induced remodeling. low expression, while interleukin‐1β (IL‐1β) high expression was determined MI by reverse‐transcription quantitative polymerase chain reaction ELISA...
Syringic acid (SA), a naturally occur-ring O‑methy-lated trihydroxybenzoic monomer extracted from Dendrobium nobile Lindl., has been demonstrated to attenuate renal ischemia‑reperfusion (I/R) injury. However, the role of SA in myocardial I/R injury is unclear. The present study aimed clarify cardioprotective effect vitro and explore potential molecular mechanisms. In study, it was revealed that pretreatment with increased viability inhibited oxidant stress H9c2 cardiomyocytes had suffered...
Pulmonary sequestration is a congenital malformation of lung development in which part the tissue separated from normal during embryonic phase and develops separately receives blood supply an aberrant systemic artery forming nonrespiratory mass. In brief, early development, certain tissues that should have atrophied been gradually absorbed are left behind due to impairment atrophy process form anomalous branches aorta, pull parts tissue, isolating them bronchi, thus separate tissue....
To investigate the value of (18)F fluorodeoxyglucose-positron emission tomography/computed tomography ((18)F FDG-PET-CT) in diagnosis and evaluation disease activity remission dermatomyositis(DM).DM patients who were admitted to Department Rheumatology, People's Liberation Army General Hospital (PLAGH) underwent FDG-PET-CT examination retrospectively reviewed from January 2012 May 2015.Gender age matched healthy controls (HC) also enrolled.The standardized uptake (SUV) proximal limb girdle...
Although laparoscopic anatomical hepatectomy (LAH) is widely adopted today, anatomic mesohepatectomy (LAMH) for patients with hepatocellular carcinoma (HCC) remains technically challenging. In this study, 6 suffering from solitary liver tumors located in the middle lobe of underwent counterclockwise modular LAMH using combined Glissonean pedicle (Takasaki approach) and hepatic vein-guided approaches. process, approach was first used to transect pedicles segment right anterior (G58) 4 (G4)....
Abstract Background Primary hepatic carcinosarcoma (HCS) is an extremely rare malignant tumor that composed of a mixture carcinomatous and sarcomatous elements. However, there have been few reported cases, especially with sufficient records to describe imaging pathological features, posing the diagnosis, treatment, prognosis HCS significant challenges for clinical physicians. Here, we report review case HCS, including combined findings, analysis pathology immunohistochemistry, which will be...
Objective To investigate the correlation between myocardial fibrosis evaluated by cardiac magnetic resonance(CMR)T1 mapping and N-terminal pro-B-type natriuretic peptide(NT-proBNP)in elderly patients with ischemic cardiomyopathy(ICM). Methods The 56 hospitalized ICM(ICM group)and 20 healthy volunteers(control group)were recruited in cardiology department of Henan Provincial People's Hospital from April 2014 to June 2017.Clinical data, serum NT-proBNP detection, CMR T1...