A5102700670- Spondyloarthritis Studies and Treatments
- Liver Disease Diagnosis and Treatment
- Venous Thromboembolism Diagnosis and Management
- Autophagy in Disease and Therapy
- Inflammasome and immune disorders
- Pharmacogenetics and Drug Metabolism
- Adipokines, Inflammation, and Metabolic Diseases
- Viral-associated cancers and disorders
- Pharmacological Effects of Natural Compounds
- Cholesterol and Lipid Metabolism
- Immune Cell Function and Interaction
- Airway Management and Intubation Techniques
- Nosocomial Infections in ICU
- Glycosylation and Glycoproteins Research
- Adipose Tissue and Metabolism
- Pituitary Gland Disorders and Treatments
- Trauma and Emergency Care Studies
- High voltage insulation and dielectric phenomena
- COVID-19 and healthcare impacts
- Platelet Disorders and Treatments
- Heparin-Induced Thrombocytopenia and Thrombosis
- Emergency and Acute Care Studies
- Hormonal Regulation and Hypertension
- Phagocytosis and Immune Regulation
- COVID-19 Clinical Research Studies
Sun Yat-sen University
2021-2025
Binzhou University
2023-2024
Binzhou Medical University
2023-2024
Central South University
2024
Chinese PLA General Hospital
2023-2024
Suzhou Municipal Hospital
2023
Nanjing Medical University
2023
Third Affiliated Hospital of Sun Yat-sen University
2023
Jinan University
2008
IHI Corporation (United States)
2003
Abstract Abnormal glucose and lipid metabolism in COVID-19 patients were recently reported with unclear mechanism. In this study, we retrospectively investigated a cohort of without pre-existing metabolic-related diseases, found new-onset insulin resistance, hyperglycemia, decreased HDL-C these patients. Mechanistically, SARS-CoV-2 infection increased the expression RE1-silencing transcription factor (REST), which modulated secreted metabolic factors including myeloperoxidase, apelin,...
B7-H6 is a novel immune checkpoint molecule that triggers NK cell cytotoxicity, but the role of N-glycosylation in poorly understood. We here identified existence different lines and exogenous expression cells by PNGase F digestion tunicamycin blockage. Subsequently, we demonstrated contains 6 functional N-linked glycosylation sites single site mutation electrophoresis. Phylogenetical structural analysis revealed N43 N208 glycan are conserved jawed vertebrates may thus contribute more to...
Abstract Background Acute thrombotic events play a major role in various cardiovascular diseases. Therefore, direct thrombus imaging can be proved beneficial for early diagnosis and prompt therapy of thrombosis. Our study investigated targeted dual‐modality cyclic arginine‐glycine‐aspartic micro bubbles (cRGD‐MBs) thrombi by fluorescence ultrasound. Methods cRGD‐MBs were prepared mechanical vibration chemical chelation methods. Results Coulter counter analysis demonstrated that the well...
The rapid advancement of Large Language Models (LLMs) in the realm mathematical reasoning necessitates comprehensive evaluations to gauge progress and inspire future directions. Existing assessments predominantly focus on problem-solving from examinee perspective, overlooking a dual perspective examiner regarding error identification correction. From we define four evaluation tasks for correction along with new dataset annotated types steps. We also design diverse prompts thoroughly evaluate...
Objective: This study aims to evaluate the impact of COVID-19 prevention and control policies on frequency emergency department (ED) visits in a large tertiary hospital central China, from January 2018 September 2023. Methods: We conducted multi-stage interrupted time series analysis investigate various epidemic weekly ED at Hunan Province, China. The period ranged 1, 2018, 30, 2023, was divided into four distinct periods: pre-epidemic, pandemic, normalized control, end control. Using...
To compare the effectiveness of small incision external articular minimally invasive osteotomy and traditional Chevron in treatment hallux valgus.
Paraganglioma (PGL) usually presents as the elevation of blood pressure and metabolic changes in patients, its common symptoms are persistent or paroxysmal hypertension. However, some patients have no typical clinical symptoms, such with non-functional PGL. Therefore, present study reviewed literature summarized rare case to provide more accurate in-depth help for diagnosis comprehensive treatment. The was a 64-year-old female epigastrium malaise 1 year aggravation 7 days. Contrast-enhanced...
OBJECTIVE: To investigate the effects of angiotensin receptor blocker (ARB) on triglyceride (TG) medoxomil metabolism and mechanism thereof. METHODS: Zucker fatty (ZF) rats lean (ZL) were fed with water containing 0.01% olmesartan , a highly specific ARB for 4 weeks. Frequently sampled intravenous glucose tolerance test was conducted to calculate area under (AUCG), insulin sensitivity index (SI), effectiveness (SG), Blood glucose, TC, TG, nonesterified acid (NEFA), HDL-C measured standard...
Abstract Backgound: Acute thrombotic events play a vital role in cardiovascular diseases. Our study aims to investigate an ultrasound microbubble fordual-modality imaging of thrombi. Methods: DID-DSPE-PEG-cRGD-Microbubbles wereprepared by mechanical vibration and Chemical chelation methods. In vivo fluorecence were performed after intravenous injection respectively. Results: This microbubbles exhibitedgood binding affinity activated platelets with significant fluorescence ultrasonic signals....
Abstract Background Primary hepatic carcinosarcoma (HCS) is an extremely rare malignant tumor that composed of a mixture carcinomatous and sarcomatous elements. However, there have been few reported cases, especially with sufficient records to describe imaging pathological features, posing the diagnosis, treatment, prognosis HCS significant challenges for clinical physicians. Here, we report review case HCS, including combined findings, analysis pathology immunohistochemistry, which will be...
Introduction: Endotracheal suction plays a crucial role in the management of mechanically ventilated patients. This study aims to evaluate clinical effectiveness and safety tubes with markings pediatric Materials Methods: A randomized assignment was carried out on cohort 52 patients who underwent mechanical ventilation Pediatric Intensive Care Unit at Third Affiliated Hospital Sun Yat-sen University, covering period from January 2022 December 2022. These were divided into two groups: an...