A5055370356- Cancer, Lipids, and Metabolism
- Metabolomics and Mass Spectrometry Studies
- Epigenetics and DNA Methylation
- Cancer, Hypoxia, and Metabolism
- Cholesterol and Lipid Metabolism
- Inflammatory mediators and NSAID effects
- Ubiquitin and proteasome pathways
- Insurance and Financial Risk Management
- Breast Cancer Treatment Studies
- RNA modifications and cancer
- Nanoplatforms for cancer theranostics
- Advancements in Transdermal Drug Delivery
- Emotional Intelligence and Performance
- Spine and Intervertebral Disc Pathology
- Genomics, phytochemicals, and oxidative stress
- Management Theory and Practice
- Credit Risk and Financial Regulations
- Protease and Inhibitor Mechanisms
- Plant-derived Lignans Synthesis and Bioactivity
- Breast Lesions and Carcinomas
- Risk and Portfolio Optimization
- Oxidative Organic Chemistry Reactions
- Probability and Risk Models
- Insurance, Mortality, Demography, Risk Management
- Gut microbiota and health
Jinan University
2006-2024
First Affiliated Hospital of Chengdu Medical College
2024
Red Cross Hospital
2023
Sun Yat-sen University
2023
South China University of Technology
2023
Sun Yat-sen University Cancer Center
2023
State Key Laboratory of Oncology in South China
2023
Guangzhou Medical University
2023
Guangzhou First People's Hospital
2023
Nanjing University
2020
Currently, treatment of chronically infected wounds still remains a big challenge; thus, novel strategy with highly efficient therapeutic effect is urgent demand. In the present work, we demonstrated that combinational use nitric oxide (NO) and deferoxamine (DFO) promising way for treating hard-to-heal wounds. As proof concept, DFO was first loaded in mesoporous polydopamine (mPDA) then functionalized by chitosan-graft-third generation poly(amidoamine) polymer terminal S-nitrosothiol groups...
Objective The primary objective of this study was to examine the levels serum EZH2 in patients diagnosed with bladder cancer, and subsequently evaluate its potential as a biomarker for both diagnosis prognosis cancer. Methods Blood samples were obtained from 115 cancer healthy persons. We measured concentrations these subjects via enzyme-linked immunosorbent assay (ELISA). To assess diagnostic performance detecting we plotted receiver operating characteristic (ROC) curves calculated their...
Enhancer of zeste homolog 2 (EZH2) is an important member the epigenetic regulatory factor polycomb group proteins (PcG) and abnormally expressed in a wide variety tumors, including osteosarcoma. Scientists consider EZH2 as attractive target for treatment osteosarcoma have found many potential EZH inhibitors, such GlaxoSmithKline 343 (GSK343). It has been reported that GSK343 can be used inhibitor different types cancer. This study demonstrated not only induced apoptosis by increasing...
As an important part of regional synthesis, the local landscape is a crucial source attractiveness for tourist destinations, in which soundscapes play notable and special role. Many studies have investigated changes economic, cultural, environmental aspects destinations under development, while little attention has been paid to how change after tourism development. To this end, we chose Lugu Lake Scenic Spot as study area explored characteristics soundscape by conducting survey residents six...
Epithelial ovarian cancer (EOC) is the fifth most common malignancy in women, with a 5-year mortality of >70% North America. As symptoms are often not observed until has spread extensively, few women diagnosed at an early stage disease. Large-scale gene expression analyses have identified molecular subtypes within high-grade variable survival rates and drug resistance. The understanding expression, mechanisms underlying processes resistances facilitated development targeted therapies....
Breast low-grade adenosquamous carcinoma is an uncommon cancer that has been neglected in genetic and pathophysiological research. Consequently, medical practitioners face challenges the effective diagnosis treatment of this condition.
Worldwide, ovarian cancer (OC) is the seventh common and second most cause of death in women. Due to high rates relapse, there an urgent need for identification new targets OC treatment. The far-upstream element binding protein 1 (FBP1) enhancer zeste homolog 2 (EZH2) are emerging proto-oncogenes that regulate cell proliferation metastasis. In present study, Oncomine data analysis demonstrated FBP1 was closely associated with development OC, Cancer Genome Atlas (TCGA) indicated a positive...
Objective. This study is to explore key immune markers and changes of microenvironment in neuropathic pain (NeuP). Method. The data sets GSE145199 GSE145226 Gene Expression Omnibus (GEO) database was used analyze, the were verified by GSE70006 GSE91396, infiltration degree cells different samples analyzed CIBERSORT analysis package. Results. In this study, we found a marker, namely, LANCL1. Regulatory axis closely related LANCL1 has also been found, miR-6325/LANCL1 axis. analysis, that...
The data sets of GSE56081 and GSE63492 in the Gene Expression Omnibus (GEO) database were used for screening analysis, key gene markers verified by GSE34095 GSE126883. Finally, infiltration immune cells analyzed MCPcounter analysis package.
Numerous studies have shown that young age is a risk factor in early breast cancer.But for stage IV cancer, it unclear whether has similar effect on patient survival.We collected and analyzed data from patients with cancer between January 2010 December 2015 SEER database.Multivariate Cox proportional hazard model was used this study.13,069 were included the analysis, of which 1,135 (≤40 years old).In multivariate analysis adjusted sociodemographic factors, clinical-pathological...
The high conductivities and good mechanical properties of hydrogel electrolyte films are critical for energy storage devices with flexibility, fast redox kinetics, long life. Herein, a low water content (6.63 wt%) film is prepared, favorable environment created, an electrochemical stability window 2.26 V ionic conductivity 2.6 mS cm-1 . exhibits folding ability, in-plane swelling, anti-freezing abilities. These benefitted by immobilizing free molecules on the abundant oxygenic groups polymer...
OBJECTIVE: To investigate the effects of angiotensin receptor blocker (ARB) on triglyceride (TG) medoxomil metabolism and mechanism thereof. METHODS: Zucker fatty (ZF) rats lean (ZL) were fed with water containing 0.01% olmesartan , a highly specific ARB for 4 weeks. Frequently sampled intravenous glucose tolerance test was conducted to calculate area under (AUCG), insulin sensitivity index (SI), effectiveness (SG), Blood glucose, TC, TG, nonesterified acid (NEFA), HDL-C measured standard...
6599 Background: Proton beam therapy (PBT) is a radiotherapy platform that purports an improved therapeutic ratio by way of rapid radiation dose fall-off. Despite this technology being hindered significant capital and patient costs, the number centres offering PBT increasing exponentially. Consensus guidelines support use in limited disease sites or on clinical trials. As patients frequently obtain information about from hospital cancer centre websites, purpose study was to evaluate direct...
<p style='text-indent:20px;'>In this paper, we study the optimal reinsurance design with default risk by minimizing VaR (value at risk) of reinsurer's total exposure. The treaty is provided. When premium principle specified to expected value and exponential principles, explicit expressions for treaties are given, respectively.
Authors of papers to proceedings from two dimensions, namely Marx labor value, value and use are be discussed for the dimensions safety philosophy thinking, analysis that "production" is unity value.This has theoretical practical significance enterprise further improve "production".This article aims at changing business' ideology just production a product or service concept economics, enterprise's dual nature, one safety's system, is, investment, human, financial, material input, ensure...