- Insect Utilization and Effects
- Tuberculosis Research and Epidemiology
- Pharmaceutical and Antibiotic Environmental Impacts
- Mycobacterium research and diagnosis
- Antibiotic Resistance in Bacteria
- Schizophrenia research and treatment
- Insect symbiosis and bacterial influences
- Genetics, Aging, and Longevity in Model Organisms
- GABA and Rice Research
- Aquaculture Nutrition and Growth
- Insect and Pesticide Research
- Metal complexes synthesis and properties
- Treatment of Major Depression
- Bioinformatics and Genomic Networks
- Aquatic life and conservation
- Insect Resistance and Genetics
- Neuroscience and Neuropharmacology Research
- Bacteriophages and microbial interactions
- Traditional Chinese Medicine Analysis
- Alzheimer's disease research and treatments
- Aquaculture disease management and microbiota
- Bioeconomy and Sustainability Development
- Insect behavior and control techniques
- Radioactive element chemistry and processing
- Selenium in Biological Systems
Huazhong Agricultural University
2009-2025
Shanghai Zhangjiang Laboratory
2022-2024
Huazhong University of Science and Technology
2024
Center of Hubei Cooperative Innovation for Emissions Trading System
2024
Jinan University
2012
Institute of Neurobiology
2001
Glutamate transporters are involved in the maintenance of synaptic glutamate concentrations. Because its potential neurotoxicity, clearance from cleft may be critical for neuronal survival. Inhibition uptake synapse has been implicated several neurodegenerative disorders. In particular, is inhibited Alzheimer's disease (AD); however, mechanism decreased transporter activity unknown. Oxidative damage brain models neurodegeneration, as well AD. by oxidative reactive oxygen species and lipid...
Introduction This study examines the optimum conversion of Wuzhishan pig manure by Black Soldier Fly Larvae (BSFL) at various phases development, as well impact gut microbiota on efficiency. Method and results In terms efficiency, BSFL outperformed growing stage (GP) group, with significantly higher survival rates (96.75%), fresh weight (0.23 g), larval rate (19.96%) compared to other groups. Notably, GP group showed significant dry matter reductions (43.27%) improved feed (2.17)....
Analysis of the protein-protein interaction network a pathogen is powerful approach for dissecting gene function, potential signal transduction, and virulence pathways. This study looks at construction global (PPI) human Mycobacterium tuberculosis H37Rv, based on high-throughput bacterial two-hybrid method. Almost entire ORFeome was cloned, more than 8000 novel interactions were identified. The overall quality PPI validated through two independent methods, high success rate 60% obtained....
Black soldier fly (BSF) larvae are often exposed to organic waste which harbors abundant zoonotic pathogens. We investigated the ability of BSF inhibit pathogens naturally found in pig manure. The populations were detected by using selective medium during conversion. Results showed that viability manure was significantly affected. After eight days conversion, Coliform undetected, and Staphylococcus aureus Salmonella spp. decreased on eighth day. Antimicrobial assays purified recombinant...
Black soldier fly (BSF) larvae are considered a promising biological reactor to convert organic waste and reduce the impact of zoonotic pathogens on environment. We analysed effects BSF Staphylococcus aureus Salmonella spp. populations in pig manure (PM), which showed that can significantly counts associated S. Then, using sterile larval system, we validated function intestinal microbiota vivo suppress pathogens, lastly, isolated eight bacterial strains from gut inhibit aureus. Results...
Black soldier fly larvae (BSFL) have potential utility in converting livestock manure into larval biomass as a protein source for feed. However, BSFL limited ability to convert dairy (DM) rich lignocellulose. Our previous research demonstrated that feeding with mixtures of 40% and 60% chicken (DM40) provides novel strategy significantly improving their efficiency DM. the mechanisms underlying efficient conversion DM40 by are unclear. In this study, we conducted holistic study on taxonomic...
The increasing prevalence of antibiotic-resistant bacteria (ARB) from animal manure has raised concerns about the potential threats to public health. bioconversion with insect larvae, such as black soldier fly larvae (BSFL, Hermetia illucens [L.]), is a promising technology for quickly attenuating ARB while also recycling waste. In this study, we investigated BSFL conversion systems chicken manure. Using metagenomic analysis, tracked and evaluated resistome dissemination risk by...
Abstract Black soldier fly (BSF, Hermetia illucens ) has been recognized as a promising insect species for sustainable conversion of organic waste into valuable biomass. Many studies have focused on the use BSF larvae to improve recycling waste. However, few conducted reproductive efficiency adults. In particular, major problems with artificial systems are directed oviposition and poor rate due inadequate sunlight. This study aimed address bottleneck by developing an effective source finding...
Antibiotic resistance in soil introduced by organic fertilizer application pose a globally recognized threat to human health. Insect may be promising alternative due its low antibiotic resistance. However, it is not yet clear how regulate microbes reduce agricultural application. In this study, we investigated and resistome under black soldier fly (BOF) pot field systems. Our study shows that BOF could stimulate ARB (antibiotic resistant − bacteria) suppressive Bacillaceae the microbiome...
Furfural acetone (FAc) is a promising alternative to currently available nematicides, and it exhibits equivalent control efficiency on root-knot nematodes with avermectin in fields. However, its effect the reproduction of nematode poorly understood. In this study, natural metabolite FAc was found exhibit reproductive toxicity Meloidogyne incognita Caenorhabditis elegans. The number germ cells C. elegans observed decrease after exposure FAc, reduction 59.9% at dose 200 mg/L. various...
The antioxidant defense is critical for the survival of intracellular pathogens such as
Cordycepin is an efficient component of Cordyceps spp, a traditional Chinese medicine widely used for healthcare in China, and has been recently acted as strong anticancer agent clinic. However, whether how it may play role combating tuberculosis, caused by Mycobacterium remains unknown. Here we report that cordycepin can kill hijacking the bacterial adenosine kinase (AdoK), purine salvage enzyme responsible phosphorylation (Ado) to monophosphate (AMP). We show poor AdoK substrate but...
The chromosome partitioning proteins, ParAB, ensure accurate segregation of genetic materials into daughter cells and most bacterial species contain their homologs. However, little is known about the regulation ParAB proteins. In this study, we found that 3-methyladenine DNA glycosylase I MsTAG(Ms5082) regulates growth cell morphology by directly interacting with MsParA (Ms6939) inhibiting its ATPase activity in Mycobacterium smegmatis. Using two-hybrid pull-down techniques combination...
Lsr2, a bacterial histone-like protein, has been shown to be clearly involved in modulating chromatin organization, compaction and global gene expression. However, the regulatory mechanism of its functions remains largely unclear. In this study, using two-hybrid technique pull-down assays, Mycobacterium smegmatis Lsr2 was detected associate with hypothetical flavoprotein, Ms4334. A further co-immunoprecipitation assay confirmed physical interaction between these two proteins vivo...
Nematodes feed on nontoxic bacteria as a food resource and avoid toxic bacteria; they distinguish them through their volatile metabolites. However, the mechanism of how nematodes recognize by metabolites is not fully understood.
The goal of this study was to research the effects Lactobacillus buchneri L3‐9 and its extracellular products on growth, immunity, intestinal microorganisms, disease resistance Aeromonas hydrophila in grass carp. A total 120 fish (80–90 g) were distributed into 12 aquariums (10 fish/aquarium) three replicates fed 1% their body weight for 21 days. carp four different diets: a control (group C), diet supplemented with 1 × 10 6 cell g −1 L. B), E), BE). Compared diet, B, E, BE diets increased...
This research was conducted to determine the effect of particle size wheat on digestibility, growth performance, and gut microbiota in growing pigs. The pigs were fed wheat–soybean meal-based diets containing 70.85% ground mean sizes 330, 430, 450, 470, 580, 670 μm. First, dry matter (DM) crud protein (CP) digestibility measured by two-step method (pepsin trypsin) vitro. Then, 30 barrows (body weight (BW):21.2 ± 1.2 kg) 6 different apparent DM, gross energy (GE), N vivo. Finally, performance...