A5103208808- Meat and Animal Product Quality
- Fungal Biology and Applications
- Advanced Chemical Sensor Technologies
- Biochemical Analysis and Sensing Techniques
- Asthma and respiratory diseases
- Sepsis Diagnosis and Treatment
- Medicinal plant effects and applications
- Intracerebral and Subarachnoid Hemorrhage Research
- Cardiac Arrest and Resuscitation
- Cardiac tumors and thrombi
- Phytochemicals and Antioxidant Activities
- Sarcoma Diagnosis and Treatment
- SARS-CoV-2 and COVID-19 Research
- Gut microbiota and health
- Allergic Rhinitis and Sensitization
- Polysaccharides and Plant Cell Walls
- Sinusitis and nasal conditions
- Gastrointestinal motility and disorders
- Ocular Oncology and Treatments
- Retinal Development and Disorders
- Vitamin D Research Studies
- Natural Antidiabetic Agents Studies
- Adipokines, Inflammation, and Metabolic Diseases
- Immunotherapy and Immune Responses
- Stress Responses and Cortisol
Capital Medical University
2025
Capital University
2025
Ningxia Hui Autonomous Region Peoples Hospital
2017-2024
Ningxia Medical University
2024
The Fourth People's Hospital of Ningxia Hui Autonomous Region
2018-2024
First Affiliated Hospital of Kunming Medical University
2024
Yangzhou University
2021-2024
Kunming Medical University
2024
Jinan University
2021-2023
Ministry of Agriculture and Rural Affairs
2022-2023
Objective: Detection of aberrant methylated genes in feces has been developed as an early screening method for colorectal cancer.The aim this study was to probe the methylation status SEPT9, BMP3, NDRG4, and SDC2 stool whether these is associated with cancer.Materials Methods: DNAs were isolated purified from cancerous non-cancerous samples cancer tissue.Gene levels quantified by methylation-specific PCR on analyzed a diagnostic model.Results: DNA NDRG4 SDC2, but not had potential detecting...
Long-term infection with Helicobacter pylori ( H. pylori) leads to elevated serum gastrin levels, which are closely related gastric cancer. Eradication of H . treat the high levels is increasingly challenged by antibiotic resistance. Dopamine (DA) receptor 1 (D R) expressed on G cells in antrum. Parietal produce DA, inhibits somatostatin (SOM) release through D 2 R mucosa. Whether targeted intervention DRs can improve after remains be explored. In this study, human tissue, pylori-infected...
This study aimed to compare the nutritive value and obesity prevention of ordinary Cordyceps militaris (CM) selenium-enriched CM (SeCM). The results indicated that Se enrichment significantly increased total carbohydrate soluble dietary fiber content, while protein insoluble content decreased. Although fat was not affected, medium long-chain fatty acids changed. Moreover, elevated secondary metabolites belonging terpenoids alkaloids, which are linked with enhanced biosynthesis metabolites....
Researches establish an indispensable role of mitochondrial dysfunction in septic cardiomyopathy. We aimed to investigate the effects long noncoding RNA (LncRNA) SOX2 overlapping transcript (SOX2OT) on observed obvious overexpression SOX2OT hearts and cardiomyocytes. Knockdown mice recovered reduced cardiac function, improved membrane potential impaired by lipopolysaccharide (LPS). overexpressed showed opposite situation. In parallel, knockdown cardiomyocytes restored potential, along with...
This study was conducted to evaluate the effect of salt brining process parameters (salt concentration 0-15%, time 4-12 h, temperature 4-20 °C) on quality sous vide cooked duck meat by a single factor combined with response surface methodology (RSM). The sensory evaluation, physicochemical indexes (color, weight loss, NaCl content, TBARS value, and texture properties), flavor characteristics were analyzed. overall mean score applied as evaluation index optimize conditions RSM, optimum...
The honey peach is popular due to its unique flavor. However, the flavor characteristics of peaches cultivated in Yangzhou and Wuxi remain unclear. In this study, profiles five famous peaches, Baifeng (YBF), Zhonghujing (YZHJ), Wanhujing (YWHJ), (WBF), (WWHJ), were investigated using gas chromatography-mass spectrometry (GC–MS) combined with odor activity values (OAVs), electronic tongue (E-tongue) sensory evaluation. A total 84 substances identified by GC–MS 17 odor-active compounds...
Scope Whole‐food‐based strategies to prevent metabolic diseases are growing interests. Agrocybe cylindracea (AC) is a major edible mushroom with high values of nutrition, but little known about its health benefits as portion whole food. Methods and Results Diet‐induced obese, C57BL/6J mice fed an high‐fat diet (HFD) or without AC (3% 5%, w/w in the diet) for 9 weeks. The results show that dietary reduced body weight, adipose accumulation, impairment glucose tolerance, lipid levels, liver...
Abstract Objective The aim of this study was to establish and validate a clinical prediction model for assessing the risk metastasis patient survival in Ewing's sarcoma (ES). Methods Patients diagnosed with ES from Surveillance, Epidemiology End Results (SEER) database period 2010-2016 were extracted, data after exclusion vacant terms used as training set ( n =767). Prediction models predicting patients' overall (OS) at 1 3 years created by cox regression analysis visualized using Nomogram...
Background Few efficacious topical therapies exist for chronic rhinosinusitis (CRS). The lack of a reproducible mouse model CRS limits the pilot testing potential novel anti-inflammatory therapies. Although ovalbumin-induced sinonasal inflammation is commonly used, it difficult to reproduce and can generate variable histologic results. In this study, we explore variation in different strains mice various inflammatory cytokines as molecular markers inflammation. Methods Allergic was generated...
Pineal region tumor is a rare intracranial tumor, and its special location leads to own characteristics. This study aimed provide some insight the medical practice for care of pineal tumor. It investigated key epidemiological characteristics survival prognosis tumors based epidemic data from SEER database. Data patients 1975 2019 were extracted database divided all into three pathologic groups: "Germ cell (GCTs)", "Pineal parenchymal (PPTs) " "Others". Patients' overall (OS) was analyzed...
Background Oxidative stress exacerbates lower airway diseases including asthma and chronic obstructive pulmonary disease (COPD); however, its role in upper (sinonasal) inflammatory disorders is less clear. Nuclear erythroid 2 p45‐related factor (Nrf2) an endogenous mechanism that upon activation invokes antioxidant response pathway via nuclear translocation upregulation of cytoprotective genes. We sought to determine whether deletion Nrf2 enhances susceptibility allergic sinonasal...
Trauma remains a tremendous medical burden partly because of increased expenditure for the management multiple organ dysfunction syndrome (MODS) developed during hospital stay. The intestinal barrier injury continues to be second insult resulting in MODS which currently lacks efficient strategies prevention. Recent studies have uncovered multi-organ protective benefits atrial natriuretic peptide (ANP) cardiovascular disease. However, role ANP prevention following severe trauma has not been...
Cardiac arrest most commonly occurs outside of the hospital, known as out-of-hospital cardiac (OHCA), and is an important global health problem. Approximately 40% has no clear cause. Hereditary arrhythmias cardiomyopathies factors contribute to arrest. The identification genetic for after its occurrence great value not only individual, but also relatives who may be at risk disease in their family. In United States, there are over 350 000 cases OHCA 200 in-hospital (IHCA) each year, Western...
<title>Abstract</title> 【Background】 To dynamically monitor the plasma melatonin and cortisol levels in patients with bipolar depressive episodes, to improve polysomnography, analyze circadian rhythm characteristics of depression, we explore value disorders diagnosed depression.【Methods】A total 54 subjects were included, comprising 16 cases 12 unipolar 11 depression remission, 15 healthy controls. High-performance liquid chromatography-tandem mass spectrometry was used detect four groups at...
Background: COVID-19, caused by SARS-CoV-2, has had a significant impact on global health. While the virus primarily affects respiratory system, intricate interplay between immune cells and remains poorly understood. This study investigates causal relationship 731 cell phenotypes COVID-19 using Mendelian randomization analysis. Methods: A bidirectional two-sample (MR) analysis was conducted genetic variants strongly associated with as instrumental variables. Data for were sourced from GWAS...
Abstract Fish soup was usually prepared in electrical stewpot instead of traditional purple clay due to its convenience nowadays; however, fish at a high temperature for long time resulted flavour deterioration. The profile crucian carp modes (traditional (TS) and commercial ceramic (CS)) low (electrical with modulation (TM 1 ‐TM 6 )) studied by sensory evaluation, gas chromatography‐mass spectrometry (GC‐MS) GC‐MS/olfactometry (GC‐MS/O). Results indicated that TM 2 (heating rate 2.44°C/min,...
This study aimed to compare the nutritive value and anti-obesity effect of ordinary Cordyceps militaris (CM) selenium-enriched CM (SeCM). The results indicated that Se enrichment significantly increased total carbohydrate soluble dietary fiber content, while protein insoluble content decreased. Although fat was not affected, medium long-chain fatty acids changed. Moreover, elevated phytochemicals belonging terpenoids alkaloids, which are linked with enhanced biosynthesis secondary...
Purpose To construct and identify the plasmid of mutant MYOC Pro356Leu in mouse. Methods 1.Transfering Red recombinantinase- expressing pKD46 was transferred to RP23-180F15 BAC clone by electroporation.2.Amplifying tThe pStart-K vector amplified PCR electroporating product electroporated into bacteria containing mMYOC. 3.PCR amplification mMyoc AfeI fragment Subcloningand then subcloned it pBluescript vector.4.Designing two oligonucleotides designed introducingthe (C T at codon 356)...