- Brucella: diagnosis, epidemiology, treatment
- Zoonotic diseases and public health
- COVID-19 epidemiological studies
- Neurotransmitter Receptor Influence on Behavior
- Animal Disease Management and Epidemiology
- Antibiotic Use and Resistance
- Synthesis and biological activity
- Synthesis and Characterization of Heterocyclic Compounds
- Attention Deficit Hyperactivity Disorder
- Quinazolinone synthesis and applications
- Pharmacological Effects of Natural Compounds
- Antibiotic Resistance in Bacteria
- Phenothiazines and Benzothiazines Synthesis and Activities
- Telomeres, Telomerase, and Senescence
- COVID-19 and healthcare impacts
- Urinary Tract Infections Management
- COVID-19 Clinical Research Studies
- Neuroscience and Neuropharmacology Research
- Beetle Biology and Toxicology Studies
- Catalytic Processes in Materials Science
- Galectins and Cancer Biology
- Metabolism, Diabetes, and Cancer
- ATP Synthase and ATPases Research
- Enzyme Catalysis and Immobilization
- Phytochemistry and biological activity of medicinal plants
Ningxia Medical University
2024-2025
The Fourth People's Hospital of Ningxia Hui Autonomous Region
2020-2025
Suizhou Central Hospital
2020-2024
Hubei University of Medicine
2010-2024
Ningxia Hui Autonomous Region Peoples Hospital
2015-2023
Taihe Hospital
2009
Wuhan University
2005-2008
Fudan University
2006
Brookhaven National Laboratory
1994-1996
Queens College, CUNY
1993
The incidence of human brucellosis has risen sharply in China but little is known about trends pastoral and agricultural areas respectively. This study aimed to analyze the annual monthly from 2004 2019. It sought identify factors contributing higher rates at specific times compare across pastoral, agricultural/pastoral, areas. Annual numbers reported cases regional between 2019 were accessed National Public Health Science Data Sharing Center, percentage change (APC) was calculated. analyzed...
Abstract Background Brucellosis is a major public health issue in China, while its temporal and spatial distribution have not been studied depth. This study aims to better understand the epidemiology of brucellosis mainland by investigating human, clustering characteristics disease. Methods Human data from China between 2012 2016 were obtained Information System for Disease Control Prevention. The autocorrelation analysis ArcGIS10.6 spatial-temporal scanning SaTScan software used identify...
Despite the considerable efforts made to address issue of brucellosis worldwide, its prevalence in dairy products continues be difficult estimate and represents a key public health around world today. The aim present study was better understand epidemiology this disease mainland China. We set out investigate yearly spatial distribution possible hotspots disease.Human data from China between 2007 2016 were collected Information System for Disease Control Prevention. A geographic information...
Abstracts Background Cancer patients are considered to be highly susceptible viral infections, however, the comprehensive features of COVID-19 in these remained largely unknown. The present study aimed assess clinical characteristics and outcomes a large cohort cancer patients. Design, Setting, Participants Data consecutive admitted 33 designated hospitals for Hubei province, China from December 17, 2019 March 18, 2020 were retrospectively collected. follow-up cutoff date was April 02, 2020....
To investigate the role of human serum albumin (hsa)_circular (circ)_0000711 in hepatocellular carcinoma (HCC). Circular ribonucleic acids (circRNAs) are proven numerous studies to play crucial tumor biology, but their roles HCC remain unknown a great extent.The circRNA expression profile microarray was employed screen differentially expressed circRNAs tissues and adjacent from patients, Reverse Transcription-quantitative Polymerase Chain Reaction (RT-qPCR) assay performed for further...
To investigate changes in the incidence of infections by extended-spectrum β-lactamase-producing Enterobacterales (ESBL-E) and analyzed whether there was an association between endogenous organism due to COVID-19 infection ESBL-E.The study a single-center retrospective case-control design. A total 107 patients infected ESBL-E during pandemic were selected as case group, while 214 uninfected 1:2 propensity score matching (PSM) acted control group. Univariate analysis, LASSO logistic...
Abstract Multidrug-resistant bacteria have become one of the most paramount health perils in 21st century. In this study, provincial-level panel data China were used to analyze relationship between bed allocation, utilization efficiency, and MDROs detection rates by quantile regression model. It was shown that number beds per 1,000 people had a negative effect on rate MRSA, VREA, VREM, PRSP, MRCNS, CTX/CRO-R ECO (regression coefficient < 0, P 0.05). The hospital positive ECO, CR-ECO, KPN,...
Analyzing the influence of bed allocation and utilization efficiency in healthcare institutions on isolation proportion Multidrug-resistant organisms (MDROs) to provide data support prevention control MDROs. In this study, provincial panel from 2014 2020 China health resource indicators, including number beds per 1,000 population, hospital rate, average stay were used analyze relationship between or MDROs by quantile regression model. It was shown that population had a negative effect...
<title>Abstract</title> <bold>Background: </bold>Talaromycosis(TSM) commonly occurs in immunodeficient or immunosuppressed individuals, but it can also occur healthy populations. The present case reports the COVID-19 together with human immunodeficiency virus(HIV) and TSM. <bold>Case Presentation:</bold> This report describes a 26-year-old male who presented fever cough for 20 days. He was diagnosed viral pneumonia through real-time RT-PCR assay chest CT scan. However, his symptoms failed to...
<title>Abstract</title> Background Brucellosis is now a public health problem that cannot be ignored in China. However, detailed study of its spatial distribution still lacking. This paper aims to understand the brucellosis China and provide new research tools bases for prevention treatment. Methods Data on incidence rate from 2012 2018 was obtained Disease Control Prevention Information System (CDCIS). ArcGIS 10.6 software used perform kriging interpolation analysis create prediction map...
Background: COVID-19, caused by SARS-CoV-2, has had a significant impact on global health. While the virus primarily affects respiratory system, intricate interplay between immune cells and remains poorly understood. This study investigates causal relationship 731 cell phenotypes COVID-19 using Mendelian randomization analysis. Methods: A bidirectional two-sample (MR) analysis was conducted genetic variants strongly associated with as instrumental variables. Data for were sourced from GWAS...
Since dl-threo-[ 11 C]methylphenidate (Ritalin) and especially the more active enantiomer, d-threo-[ C]methylphenidate, have favorable properties for PET studies,we prepared two radioiodinated analogs of methylphenidate, p-[ 123 I]icdomethylphenidate m-[ I]iodo-p-hydroxymethylphenidate with a view to evaluating them as potential SPECT tracers. To prepare I]iodomethylphenidate, p-tributyltin derivative was from previously reported p-bromomethylphenidate reacted under acidic conditions I-123...
The title compound, C(17)H(14)ClN(7), crystallizes with two independent mol-ecules in the asymmetric unit. Inter-molecular N-H⋯N and C-H⋯N hydrogen bonds contribute to stability of crystal structure. In addition, weak C-H⋯π π-π stacking [centroid-centroid distances 3.699 (8) (6) Å] interactions are observed.