A5083383687- biodegradable polymer synthesis and properties
- Polymer composites and self-healing
- Advanced Polymer Synthesis and Characterization
- Multiple Myeloma Research and Treatments
- Crystallization and Solubility Studies
- Synthesis and properties of polymers
- Lignin and Wood Chemistry
- X-ray Diffraction in Crystallography
- Protein Degradation and Inhibitors
- Advanced biosensing and bioanalysis techniques
- Polymer crystallization and properties
- Synthetic Organic Chemistry Methods
- Click Chemistry and Applications
- Chemical Synthesis and Analysis
- Radioactive element chemistry and processing
- Vanadium and Halogenation Chemistry
- Chemistry and Chemical Engineering
- Polymer Nanocomposites and Properties
- Luminescence and Fluorescent Materials
- Magnolia and Illicium research
- Cyclopropane Reaction Mechanisms
- Organic Electronics and Photovoltaics
- History and advancements in chemistry
- Epoxy Resin Curing Processes
- Carbon dioxide utilization in catalysis
Texas Tech University
2024-2025
Massachusetts Institute of Technology
2020-2024
Robert Bosch (Germany)
2019
Laboratoire de Chimie Moléculaire et Thioorganique
2019
The University of Melbourne
2018
Texas A&M University
2015-2017
Mitchell Institute
2016-2017
College Station Medical Center
2016-2017
Materials Science & Engineering
2016
Institute of Chemical Engineering
2016
Convenient strategies for the deconstruction and reprocessing of thermosets could improve circularity these materials, but most approaches developed to date do not involve established, high-performance engineering materials. Here, we show that bifunctional silyl ether, i.e., R'O-SiR2-OR'', (BSE)-based comonomers generate covalent adaptable network analogues industrial thermoset polydicyclopentadiene (pDCPD) through a novel BSE exchange process facilitated by low-cost food-safe catalyst...
"Drop-in" additives that introduce chemically cleavable bonds into thermosets without compromising thermomechanical properties could enable triggered material deconstruction and enhanced sustainability. While the installation of strands commercial thermoset polydicyclopentadiene (pDCPD) using comonomers facilitates chemical deconstruction, these can lower material's glass transition temperature (Tg). By contrast, crosslinkers pDCPD maintain or potentially increase Tg but does not facilitate...
Eleftheria Roumeli and Samantha L. Kristufek introduce the Materials Advances themed collection on advancements in high-performance sustainable polymers: from bio-derived monomers to dynamic materials.
Elastomeric polymer films synthesized through thiol–ene chemistry, suitable in applications as coatings and adhesives due to their ease of preparation superior physical properties, are traditionally derived from petroleum sources. Of recent interest is the exploration sustainable alternatives for precursors these materials. Here, we report synthesis networks photoinitiated reaction between allylated plant-based phenolic acids (salicylic acid 4-hydroxybenzoic acid) a multifunctional thiol,...
The synthesis and physical properties of thiol–ene elastomers derived from plant-based phenolic acids were explored. Phenolic varying functionality (ranging 2 to 4 hydroxyl carboxyl groups per molecule) relative placement functional (ortho, meta, para) allylated subsequently reacted with a multifunctional thiol using photoinitiator. thermal mechanical behaviors the resulting characterized. networks difunctional exhibited narrow glass transitions (indicating high degree network homogeneity)...
The natural compound, isosorbide has been functionalized and rapidly cross-linked using thiol–ene click chemistry to afford an optically-transparent, flexible elastomer.
Abstract Phenolische Materialien sind seit langem für ihre Verwendung in Farbtinten, Holzbeschichtungen und zur Ledergerbung bekannt. In letzter Zeit ist jedoch ein wachsendes Interesse an der Entwicklung moderner Werkstoffe aus phenolischen Bausteinen zu verzeichnen. Die intrinsischen Eigenschaften von Verbindungen, wie Metallchelat‐Bildung, Wasserstoffbrücken, pH‐Ansprechverhalten, Redoxpotentiale, Radikalfänger, Polymerisation Lichtabsorption, haben sie einer eigenständigen Klasse...
Prodrugs engineered for preferential activation in diseased versus normal tissues offer immense potential to improve the therapeutic indexes (TIs) of preclinical and clinical-stage active pharmaceutical ingredients that either cannot be developed otherwise or whose efficacy tolerability it is highly desirable improve. Such approaches, however, often suffer from trial-and-error design, precluding predictive synthesis optimization. Here, using bromodomain extra-terminal (BET) protein...
Abstract The natural polyphenolic compound quercetin was functionalized and cross‐linked to afford a robust epoxy network. Quercetin selectively methylated with glycidyl ether moieties using microwave‐assisted reaction on gram scale the desired monomer (Q). This quercetin‐derived treated nadic methyl anhydride (NMA) obtain network (Q‐NMA). thermal mechanical properties of this naturally derived were compared those conventional diglycidyl bisphenol A‐derived counterpart (DGEBA‐NMA). Q‐NMA had...
Bis(imino)pyridine (BIP) iron alkoxide complexes act as catalysts to efficiently polymerize N-carboxyanhydrides (NCAs), including γ-benzyl-l-glutamate NCA (BLG-NCA) and sarcosine (Sar-NCA), at room temperature. Reaction rates were greatly enhanced with the addition of mild Lewis acids, such [CoCp2][BArF24], which work cooperatively iron-based facilitate polymerization. The reactivity (2,6MeBIP)FeOCH2C(CH3)3 Sar-NCA was combined its known for ε-caprolactone polymerization form diblock...
Honokiol, a highly functional phenolic- and alkenyl-containing neolignan natural product isolated from<italic>Magnolia</italic>plants, is an interesting bio-based resource which shown to be useful as monomer for the synthesis of poly(honokiol carbonate) (PHC).
A novel class of chromophoric polyelectrolytes bearing phosphonium moieties in their backbones has been prepared to incorporate metal-binding 2,2′-bipyridyl (bipy) units. The effect metal ion binding on the photophysical properties polyelectrolyte was probed. By ions polycation, relative charge loading could be progressively increased as a strategy control its supramolecular assembly with polyanions. metallated and metal-free were utilized layer-by-layer self-assembly poly(acrylic acid) or...
Antibody drug conjugates (ADCs), which feature a monoclonal antibody (mAb) for cell targeting linked to cytotoxic payload killing, are remarkably effective class of targeted therapeutics. Despite their success, however, ADCs typically rely on highly potent payloads, precluding the use less payloads and broader range mechanisms action (MoA).1-4 Moreover, emerging perspective that passive play roles in ADC function vivo suggests opportunities engineer new based stable prodrug scaffolds with...
A concise preparation and characterization of substituted 1-{[(Z)-1-phenyl-2-phenyliodonio)vinyl]oxy}pyridinium ditosylates is presented. Determination the X-ray crystal structure reveals a pseudo-square planar molecular geometry about iodine.
Abstract Thermoset toughness and deconstructability are often opposing features; simultaneously improving both without sacrificing other mechanical properties (e.g., stiffness tensile strength) is difficult, but, if achieved, could enhance the usage lifetime end‐of‐life options for these materials. Here, a strategy that addresses this challenge in context of photopolymer resins commonly used 3D printing glassy, acrylic thermosets introduced. It shown incorporating bis‐acrylate...