A5101545575- RNA modifications and cancer
- S100 Proteins and Annexins
- Epigenetics and DNA Methylation
- Wnt/β-catenin signaling in development and cancer
- RNA Research and Splicing
- Ferroptosis and cancer prognosis
- Cancer-related gene regulation
- Angiogenesis and VEGF in Cancer
- Vascular Tumors and Angiosarcomas
- Inflammatory Biomarkers in Disease Prognosis
- Glioma Diagnosis and Treatment
- Polyamine Metabolism and Applications
- Autophagy in Disease and Therapy
- Liver physiology and pathology
- Tissue Engineering and Regenerative Medicine
- Extracellular vesicles in disease
- Photoreceptor and optogenetics research
- TGF-β signaling in diseases
- Hippo pathway signaling and YAP/TAZ
- PI3K/AKT/mTOR signaling in cancer
- Nutrition, Genetics, and Disease
- Ubiquitin and proteasome pathways
- Rheumatoid Arthritis Research and Therapies
- Sarcoma Diagnosis and Treatment
- Cancer Risks and Factors
East China University of Science and Technology
2025
First Affiliated Hospital of Bengbu Medical College
2019-2023
First Affiliated Hospital of Xi'an Jiaotong University
2022
Huazhong University of Science and Technology
2008-2021
Union Hospital
2013-2021
Affiliated Hospital of Zunyi Medical College
2019
Changzhou No.2 People's Hospital
2018
Nanjing Medical University
2018
Tianjin Medical University Cancer Institute and Hospital
2012-2015
Tianjin Medical University
2015
// Tong Wang 1,* , Jie Yuan Zhang 1 Ran Tian Wei Ji Yan Zhou Yi Yang Weijie Song Fei and Ruifang Niu Tianjin Medical University Cancer Institute Hospital, National Clinical Research Center for Cancer, The Key Laboratory of Breast Prevention Therapy, Ministry Education, Tianjin, PR China * These authors have contributed equally to this work Correspondence to: Niu, email: Zhang, Keywords : Anxa2, breast cancer, epithelial–mesenchymal transition, epidermal growth factor receptor Received...
Background: Microvesicles (MVs) are produced through the outward vesicles budding and fission from cell surface. Recently, it was discovered that extracellular MVs circulate in bodily fluids of cancer patients could serve as potential diagnos
Cancer stem cells (CSCs) are regarded as the root of tumor recurrence and distant metastasis, well major cause resistance to conventional cancer therapies. Elucidating mechanism regulating CSCs is great significance for development CSCs-targeting therapy strategies. YAP/TAZ identified key regulators CSCs-related traits on breast cells; however, upstream regulatory Hippo kinases cascade involved in remains elusive. In this study, we found that low expression RICH1 was associated with poor...
Methylxanthine derivatives, such as caffeine and theophylline, enhance cell apoptosis autophagy reportedly induce the activity of phosphatase tensin homologue (PTEN) inhibit mammalian target rapamycin (mTOR). This study investigated impacts theophylline on gastric cancer using a line (MGC-803) nude mouse model. Peritumoural tumour tissues were collected from five patients diagnosed with carcinoma who underwent laparoscopic radical gastrectomy at our hospital. Autophagy was suppressed in...
Head and neck squamous cell carcinoma (HNSCC), a tumor included oral cavity, lips, larynx, oropharynx, the nasopharynx et al. The division cycle-associated (CDCA) protein family (CDCA1-8) critical for normal function cancer proliferation. We explored mutation signatures expression levels of various CDCAs in detail HNSCC. A comprehensive bioinformatics analysis pipeline based on copy number gene expressions data from patients with HNSCC order to given new insights into possible functions...
Background: Epigenetic changes are tightly linked to tumorigenesis development and malignant transformation’ However, DNA methylation occurs earlier is constant during tumorigenesis. It plays an important role in controlling gene expression cancer cells. Methods: In this study, we determining the prognostic value of molecular subtypes based on status breast samples obtained from The Cancer Genome Atlas database (TCGA). Results: Seven clusters 204 corresponding promoter genes were identified...
Abstract Our study aimed to explore the potential mechanisms of KIF23 regulating function in progression nasopharyngeal carcinoma and pinpoint novel therapeutic targets for clinical treatment patients. The mRNA protein level was measured using quantitative real-time PCR western blot. influence on tumor metastasis growth determined through vivo vitro experiments. regulatory were illustrated chromatin immunoprecipitation assay. found be overexpressed samples, its expression associated with...