A5101506803- Advanced Battery Materials and Technologies
- Advancements in Battery Materials
- Advanced Drug Delivery Systems
- Drug Solubulity and Delivery Systems
- Ultrasound and Hyperthermia Applications
- Advancements in Transdermal Drug Delivery
- Advanced Battery Technologies Research
- Catalytic Processes in Materials Science
- Ultrasound and Cavitation Phenomena
- Tribology and Lubrication Engineering
- Photoacoustic and Ultrasonic Imaging
- Gear and Bearing Dynamics Analysis
- Supercapacitor Materials and Fabrication
- Catalysis and Hydrodesulfurization Studies
- Advanced battery technologies research
- Polyoxometalates: Synthesis and Applications
- MXene and MAX Phase Materials
- Magnetic Bearings and Levitation Dynamics
- Metallic Glasses and Amorphous Alloys
- biodegradable polymer synthesis and properties
- Carbon Dioxide Capture Technologies
- Ultrasound Imaging and Elastography
- Retinal Diseases and Treatments
- Ocular Surface and Contact Lens
- Inhalation and Respiratory Drug Delivery
Center for Drug Evaluation and Research
2018-2024
United States Food and Drug Administration
2018-2024
Ministry of Transport
2023-2024
Central South University
2022-2024
Fujian Agriculture and Forestry University
2024
University of Pittsburgh Medical Center
2024
University of Hong Kong
2019-2023
China International Science and Technology Cooperation
2023
Chongqing Medical University
2023
Children's Hospital of Chongqing Medical University
2023
Poly(lactic-co-glycolic acid) (PLGA) has been used for long-acting injectable drug delivery systems more than 30 years. The factors affecting the properties of PLGA formulations are still not clearly understood. release kinetics microparticles influenced by many parameters associated with formulation composition, manufacturing process, and post-treatments. Since have explainable using measurable properties, formulating desired extremely difficult. Of various glass transition temperature, Tg,...
Constructing heterojunctions and hollow multi‐shelled structures can render materials with fascinating physicochemical properties, have been regarded as two promising strategies to overcome the severe shuttling sluggish kinetics of polysulfide in lithium–sulfur (Li–S) batteries. However, a single strategy only take limited effect. Modulating catalytic hosts synergistic effects are urgently desired. Herein, Mn 3 O 4 ‐MnS heterogeneous spheres meticulously designed by controlled sulfuration 2...
Cardiotoxicity is the major dose-limiting factor in chemotherapeutic use of doxorubicin (Dox). A delivery vehicle that can be triggered to release its payload tumoral microvasculature but not healthy tissue would help improve therapeutic window drug. Delivery strategies combining liposomal encapsulated Dox (LDox), microbubbles (MBs), and ultrasound (US) have been shown efficacy LDox, much remains known about mechanisms US conditions maximize cytotoxicity using this approach. In study, we...
With a stable operating potential and high theoretical specific capacity, bismuth metal is promising candidate as the anode for sodium-ion batteries (SIBs). However, its rate capability, long cycling stability, sluggish kinetics, electrode structure stability still needs to be significantly improved. Herein, three-dimensional porous bismuth/nitrogen-doped carbon composite (Bi/N–C) was prepared via scalable facile solution combustion synthesis (SCS) method. The open allows fast Na+ transport...
Abstract Li 3 VO 4 is a promising anode material for lithium‐ion batteries, but suffers from low electronic conductivity. Here we demonstrated facile solid‐state method to synthesize carbon‐coated (LVO/C) enhance its conductivity and electrochemical performance. The LVO/C composites exhibit preferable specific capacity, desirable cycle performance suitable rate than the carbon‐free . A high reversible capacity of 456 mAh/g 400 can be maintained up 100 cycles 500 at 1 C (92.2 % 80 retention...
Sandostatin LAR (SLAR) is an injectable long-acting release (LAR) microsphere formulation for octreotide based on a biodegradeable glucose star copolymer of d,l-lactic and glycolic acids (PLGA-glu), which primarily used the treatment patients with acromegaly. There currently no generic SLAR approved in United States despite expiration patent coverage. To understand better this important formulation, was assessed its composition physical–chemical properties. Octreotide kinetics monitored...
The development of Li–S batteries (LSBs) is largely impeded by sluggish redox kinetics and notorious polysulfide shuttling. Herein, hierarchical MoC@Ni–NCNT arrays are reported as a multifunctional sulfur host in batteries, which comprised flexible carbon fiber cloth substrate decorated with vertical MoC porous nanorods rooted interconnected nitrogen-doped nanotubes (NCNTs). In the designed host, inner backbone (composed nanoparticles) along situ-grafted interwoven NCNT shell can greatly...
As a next-generation anode material for lithium batteries, Li metal suffers from inherent drawbacks such as infinite volume expansion and uneven plating/stripping. Herein, we propose lightweight lithiophilic Prussian blue analogue (PBA) with honeycomb-like structure on Cu foam by self-assembly method to address these issues. The unique architecture could provide enlarged surface areas abundant deposition sites homogenizing Li+ flux during plating. Consequently, the elaborate PBA-decorated...
Tashinone IIA loaded solid lipid nanoparticles (TA-SLN) coated with poloxamer 188 was prepared by emulsification/evaporation. The TA-SLN characterized transmission electron microscope and dynamic light scattering (DLS). results showed that the had an average diameter of 98.7 nm a zeta potential − 31.6 mv drug loading 4.6% entrapment efficiency 87.7%. In vitro release experiment from in accordance Weibull equation. best model fitting experimental data two-compartment open first-order. area...