- Drug Solubulity and Delivery Systems
- Advanced Drug Delivery Systems
- Advancements in Transdermal Drug Delivery
- Nanoparticle-Based Drug Delivery
- Lipid Membrane Structure and Behavior
- Surfactants and Colloidal Systems
- Ocular Surface and Contact Lens
- Analytical Chemistry and Chromatography
- Analytical Methods in Pharmaceuticals
- Protein purification and stability
- Computational Drug Discovery Methods
- RNA Interference and Gene Delivery
- Forensic Toxicology and Drug Analysis
- Antibiotics Pharmacokinetics and Efficacy
- Protein Interaction Studies and Fluorescence Analysis
- Electrospun Nanofibers in Biomedical Applications
- biodegradable polymer synthesis and properties
- Innovative Microfluidic and Catalytic Techniques Innovation
- Nanoparticles: synthesis and applications
- Dermatology and Skin Diseases
- Advanced Polymer Synthesis and Characterization
- Drug Transport and Resistance Mechanisms
- Opioid Use Disorder Treatment
- Field-Flow Fractionation Techniques
- Pain Management and Opioid Use
Center for Drug Evaluation and Research
2016-2025
Quality Research
2015-2025
United States Food and Drug Administration
2015-2025
Food and Drug Administration
2024-2025
Duke University
2025
Sichuan University
2024
Louisiana State University Health Sciences Center New Orleans
2011-2024
Wenzhou Medical University
2011-2024
Government of the United States of America
2023
Minhang District Central Hospital
2022
Quality control of pharmaceutical and biopharmaceutical products, verification their safety efficacy, depends on reliable measurements critical quality attributes (CQAs). The task becomes particularly challenging for drug products vaccines containing nanomaterials, where multiple complex CQAs must be identified monitored. To reduce (i) the risk measurement bias (ii) uncertainty in decision-making during product development, combination orthogonal complementary analytical techniques are...
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTElectrochemical oxidation and nucleophilic addition reactions of metallocenes in electrospray mass spectrometryXiaoming. Xu, Steven P. Nolan, Richard B. ColeCite this: Anal. Chem. 1994, 66, 1, 119–125Publication Date (Print):January 1994Publication History Published online1 May 2002Published inissue 1 January 1994https://pubs.acs.org/doi/10.1021/ac00073a021https://doi.org/10.1021/ac00073a021research-articleACS PublicationsRequest reuse...
In recent times, tremendous progress has been evidenced by the advancements in various methods of generating three-dimensional (3D) porous scaffolds. However, applicability most traditional approaches intended for these biomimetic scaffolds is limited due to poor resolution and strict requirements choosing materials. this work, we fabricated 3D based on composite inks gelatin (Gel), nano-hydroxyapatite (n-HA), poly(lactide-co-glycolide) (PLGA) using an innovative hybrid strategy printing...
β-Ga2O3, a semiconductor material, has attracted considerable attention given its potential applications in high-power devices, such as high-performance field-effect transistors. For decades, β-Ga2O3 been processed through chemical mechanical polishing (CMP). Nevertheless, the understanding of effect OH- on CMP with an alkaline slurry remains limited. In this study, substrates were successively subjected to (MP), and etching. Then, investigate changes that occurred surfaces samples, samples...
Metal–organic frameworks (MOFs), a class of porous nanomaterials, have been widely used in gas adsorption-based applications due to their high porosities and chemical tunability. To facilitate the discovery high-performance MOFs for different applications, variety machine learning models developed predict adsorption capacities MOFs. Most predictive are using traditional algorithms. However, continuously increasing sizes MOF datasets complicated relationships between make deep suitable...
A newly invented probe accessory for fast electrochemistry/electrospray mass spectrometry (EC/ESMS) is presented and evaluated. The device features a low-volume, three-electrode electrochemical cell which has been designed with minimum distance between the working electrode "Taylor cone" inherent to electrospray process. This configuration limits time generation of ions spectrometric analysis an absolute minimum. fused-silica layer insulates microcylinder from sample solution until...