A5047614446- Steroid Chemistry and Biochemistry
- Phytochemistry and Bioactive Compounds
- Phytochemical Studies and Bioactivities
- Intimate Partner and Family Violence
- Injury Epidemiology and Prevention
- Trauma and Emergency Care Studies
- Forensic Toxicology and Drug Analysis
- Cancer Immunotherapy and Biomarkers
- Sexual Assault and Victimization Studies
- Aortic Disease and Treatment Approaches
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Homicide, Infanticide, and Child Abuse
- Radiomics and Machine Learning in Medical Imaging
- Receptor Mechanisms and Signaling
- Cannabis and Cannabinoid Research
- Corporate Governance and Law
- Colorectal Cancer Treatments and Studies
- Analytical Methods in Pharmaceuticals
- Elder Abuse and Neglect
- Opioid Use Disorder Treatment
- Pneumocystis jirovecii pneumonia detection and treatment
- Radiation Dose and Imaging
- Amino Acid Enzymes and Metabolism
- Analytical Chemistry and Chromatography
- European and International Contract Law
Brigham and Women's Hospital
2017-2025
Lahey Medical Center
2020-2024
University of the West of England
2020-2024
Wheaton College - Illinois
2023
Boston University
2023
Lahey Hospital and Medical Center
2020-2022
Tufts University
2022
Harvard University
2018-2021
Bergman Clinics
2021
University of California, San Diego
2021
Background Intimate partner violence (IPV) is a global social and public health problem, but published literature regarding the exacerbation of physical IPV during coronavirus disease 2019 (COVID-19) pandemic lacking. Purpose To assess incidence, patterns, severity injuries in victims COVID-19 2020 compared with prior 3 years. Materials Methods The demographics, clinical presentation, injuries, radiologic findings patients reporting abuse arising from statewide between March 11 May 3, 2020,...
Cytokinin-active ribonucleosides have been isolated from tRNA of whole spinach (Spinacia oleracea L.) leaves and chloroplasts. The leaf blades contained: 6-(4-hydroxy-3-methyl-2-butenylamino)-9-beta-d-ribofuranosylpurine (cis trans isomers), 6-(3-methyl-2-butenylamino)-9-beta-d-ribofuranosylpurine, 6-(4-hydroxy-3-methyl-2-butenylamino)-2-methylthio-9-beta-d -ribofuranosylpurine isomers). A method for isolation large amounts intact chloroplasts was developed subsequently used the chloroplast...
The past decade has witnessed a change in landscape of cancer management with the advent precision oncology. Immune checkpoint inhibitors (ICIs) have revolutionized treatment and played an important role improving patient survival. While patients are living longer, ICIs sometimes associated adverse effects, some which could be fatal. Radiologists can play crucial by early identification these effects during restaging scans. Our paper focuses on imaging features commonly occurring ICI...
The potential of chemical ionization mass spectrometry for the characterization naturally occurring and semi-synthetic cardiac glycosides has been investigated. Methane, isobutane ammonia were used as reactant gases. With exception ouabain, spectra examined in this work contained abundant [M+NH4]+ ions fragment formed by cleavage glycoside bonds. Ammonia was found to provide a rapid sensitive method products glycosidation reactions. In contrast, methane glycosides, with did not contain...
OBJECTIVE. The purpose of this study is to assess the frequency atypical response patterns in oncology patients treated with programmed cell death protein-1 inhibitor nivolumab. MATERIALS AND METHODS. This retrospective included 254 nivolumab alone or combination, from January 2013 through August 2017. A blinded reader prospectively assessed treatment response. Among 166 (65%) who experienced a clinical benefit (defined as stable disease, partial response, complete best response), four were...
Background: Although pleural effusions are common among patients with acute heart failure, the relevance of effusion size assessed on thoracic ultrasound has not been investigated systematically. Methods: In this prospective observational study, we included hospitalised for failure and performed a early after admission (thoracic 1) at discharge 2) independently routine clinical management. A semiquantitative score was applied offline blinded to findings categorise monitor size. Results:...
Intravenous injection of crude marijuana extract led to development an acute illness with multisystem involvement. Gastrointestinal manifestations consisted severe vomiting, diarrhea, and crampy abdominal pain. Hypotension, tachycardia, peripheral vasodilation constituted the main cardiovascular disease. Moderate azotemia oliguria, presumed be prerenal origin, were present rapidly resolved administration intravenous fluids. Hematologic leukocytosis a left shift, thrombocytopenia, prolonged...
The ability of a series new cardenolide analogs to produce positive inotropic effect in isolated, driven, guinea-pig atria was determined. were all derivatives digitoxigenin and prepared by replacing the C17β-lactone ring with open-chain moieties. A range potency observed varying from compounds activities comparable that parent molecule, digitoxigenin, those which inactive or produced negative effect. All active toxic effects at doses close maximum stimulant Structure-activity relationships...
OBJECTIVE. The purpose of this study is to assess the most common causes reverse halo sign (RHS) in immunocompromised patients and identify clinicoradiologic features that help achieving a specific diagnosis. MATERIALS AND METHODS. This retrospective included 70 with hematologic malignancy, neutropenia, or history solid organ transplant stem cell who had RHS at chest CT. Absolute neutrophil count, imaging RHS, presence pleural effusions were noted correlated A decision tree was constructed...
Disasters are becoming more frequent and destructive while the consequences for incarcerated persons have grown increasingly visible. Simultaneously, scholars, individuals, communities grappling with police brutality systemic anti-Black racism in criminal legal system by engaging concept of abolition. In this article we demonstrate that these issues not disconnected argue abolition prison industrial complex (PIC) would mitigate impacts disasters their communities. Incarceration undermines...