Yu Zai

ORCID: 0000-0002-5813-8753
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About
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Research Areas
  • Antimicrobial Peptides and Activities
  • Biochemical and Structural Characterization
  • Invertebrate Immune Response Mechanisms
  • Lipid Membrane Structure and Behavior
  • Plant Stress Responses and Tolerance
  • Mycorrhizal Fungi and Plant Interactions
  • Aquaculture disease management and microbiota
  • Phytochemicals and Antioxidant Activities
  • Plant biochemistry and biosynthesis
  • Seedling growth and survival studies
  • Botanical Research and Applications
  • Chemical Synthesis and Analysis

Jiangsu Second Normal University
2021-2024

University of Macau
2021-2022

Queen's University Belfast
2019-2021

Temporin is an antimicrobial peptide (AMP) family discovered in the skin secretion of ranid frog that has become a promising alternative for conventional antibiotic therapy. Herein, novel temporin peptide, Temporin-PF (TPF), was successfully identified from Pelophylax fukienensis. It exhibited potent activity against Gram-positive bacteria, but no effect on Gram-negative bacteria. Additionally, TPF aggregation effects different solutions. Three analogs were further designed to study...

10.3390/ijms22094509 article EN International Journal of Molecular Sciences 2021-04-26

DMPC-10A (ALWKKLLKK-Cha-NH2) is a 10-mer peptide derivative from the N-terminal domain of Dermaseptin-PC which has shown broad-spectrum antimicrobial activity as well considerable hemolytic effect. In order to reduce and improve stability endogenous enzymes, D-amino acid enantiomer (DMPC-10B) was designed by substituting all L-Lys L-Leu with their respective D-form amino residues, while Ala1 Trp3 remained unchanged. The exhibited similar potency parent but exerted lower cytotoxicity...

10.3390/antibiotics9090627 article EN cc-by Antibiotics 2020-09-21

Amphibian skin secretion is an ideal source of antimicrobial peptides that are difficult to induce drug resistance due their membrane-targeting mechanism as a new treatment scheme. In this study, natural peptide Temporin-1CEh was identified by molecular cloning and mass spectrometry from the secretions Chinese forest frog (Rana chensinensis). Through study structure biological activity, it found helical Temporin family, possessed good anti-Gram-positive bacteria activity through membrane...

10.3390/pharmaceutics14030604 article EN cc-by Pharmaceutics 2022-03-10

Improving floral scent quality is an important goal in Malus breeding. However, the inheritance regularity for volatile components of remains unclear. In this study, compounds and characteristics five taxa with clearly defined parent–progeny relationships were analyzed by sensory evaluation, electronic nose, gas chromatography–mass spectrometry. A total 51 identified taxa. M. ioensis showed highest intensity maximum content (8247.59 ng·g−1 FW·h−1). Compared to its progenies ‘Lemoinei’,...

10.3390/agronomy15010045 article EN cc-by Agronomy 2024-12-27

The aim of this study was to investigate the effect Glomus mosseae (G. mosseae) on Na+ intercept ability in root tissues Kosteletzkya virginica (K. avirginica) grown under salt stress. Pot experiments greenhouse were carried out K. avirginica inoculated with 1% NaCl Na+, K+ concentrations, distribution and growth parameters analyzed. Salinization reduced phosphorus (P) chlorophyll contents, shoot dry weight. Salinity dramatically increased but decreased contents / ratio significantly (p <...

10.3329/bjb.v53i4.78371 article EN Bangladesh Journal of Botany 2024-12-30
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