A5084552713- Immune Cell Function and Interaction
- CAR-T cell therapy research
- Bladder and Urothelial Cancer Treatments
- Immunotherapy and Immune Responses
- Epigenetics and DNA Methylation
- Chronic Lymphocytic Leukemia Research
- Biochemical Analysis and Sensing Techniques
- PI3K/AKT/mTOR signaling in cancer
- Cancer, Hypoxia, and Metabolism
- Sensory Analysis and Statistical Methods
- Colorectal Cancer Screening and Detection
- Systemic Lupus Erythematosus Research
- Renal Diseases and Glomerulopathies
- SARS-CoV-2 and COVID-19 Research
- Cancer Research and Treatments
- Metabolism, Diabetes, and Cancer
National Chung Hsing University
2021-2022
Changhua Christian Hospital
2021-2022
Weatherford College
2022
Wan Fang Hospital
2020
Taipei Municipal YangMing Hospital
2020
Tunghai University
2020
Bruton's tyrosine kinase (BTK) has been discovered to serve a critical role in the survival and infiltration of B-cell lymphoma. Recently, it was reported that BTK inhibitors exerted potential beneficial effects against numerous types solid tumor, including glioblastoma multiforme breast cancer; however, whether is crucial for progression bladder cancer (BLCA) remains unclear. The present study investigated vitro function stemness properties BLCA cells. Furthermore, therapeutic standard...
Bladder cancer (BLCA, urothelial bladder cancer) is one of the most common malignancies with increasing incidence and mortality worldwide. Poor diagnosis limitation treatment still an unmet need in clinical practice. γδ T-Cells have been paid attention because their potent cytotoxicity against tumors. Herein, we investigated cytolytic effect T-cells combination chemotherapeutic drug, carboplatin, BLCA cells.The standard protocol for induction expansion peripheral blood mononuclear...
Background and objectives: Type 2 diabetes mellitus (T2DM) is becoming increasingly prevalent worldwide associated with increased incidence of kidney cancer bladder (BC). However, studies have produced conflicting results. Therefore, we retrospectively evaluated the BC in T2DM patients using Taiwan National Health Insurance Research Database (NHIRD). Materials Methods: We included 31,932 a diagnosis study group 63,864 age- sex-matched without at ratio 1:2 control group. The primary outcome...
Since the mass vaccination for COVID-19, several case reports indicated risk of autoimmune disease flare-ups after vaccination. Among them, COVID-19 vaccine-induced glomerular diseases have drawn attention worldwide. The cases demonstrating association between mRNA vaccine and IgA nephropathy (IgAN) exacerbation had been noticed. Mostly mentioned, usually occurred second dose.We present a Taiwanese female with IgAN who developed gross hematuria within only six hours first dose Moderna...
Ovarian cancer (OC) is typically diagnosed at an advanced stage with limitations for cure. Cytokine-induced killer (CIK) T cell therapy exerts significant cytotoxic effects against cells and reduces the adverse of chemotherapy. Herein, we performed a flow cytometry-based method to evaluate cytotoxicity peripheral blood mononuclear cells-derived CIK OC cells.The were induced expanded using interferon-γ/IL-2-based xeno-free medium system. The or carboplatin was examined.The showed NK-like...
Diabetic Mellitus (DM) is a widespread chronic disease around the world, among which type 2 DM (T2DM) shared majority. It caused multiple severe complications and consequently high mortality rate. overwhelm jeopardize patient’s quality of life. In response to threats such complications, some nutraceuticals were developed, including highly praised bitter melon peptide (BMP). This study aims apply structural equation model in HBM. A theoretical had been developed on health belief (HBM), test...
Prostate cancer (PC) is one of the major diseases that affects male health and ranks as second most frequent in men worldwide. Although newly-diagnosed PCs are well-differentiated tumors with a high cure probability, there some patients aggressive malignancies show potential for recurrence metastasis. Cytotoxic T lymphocytes specific immune effector cell population mediates responses against cancer.In present study, cytotoxicity peripheral blood mononuclear cells (PBMCs)-derived γδ...
Background/Aim: Cancer stem cells (CSCs) have been suggested playing a crucial role in the tumorigenesis and tumor progression. Clinically, concurrent chemoradiotherapy (CCRT) after transurethral resection of bladder is widely accepted treatment option for high-grade urothelial carcinoma (UC); however, proportion UC patients still suffer from recurrence metastasis. In present study, we investigated stemness properties with respect to various disease stages. The metastatic capability...