A5018453933- Health Systems, Economic Evaluations, Quality of Life
- Pharmaceutical Economics and Policy
- Statistical Methods in Clinical Trials
- Hemophilia Treatment and Research
- Atrial Fibrillation Management and Outcomes
- Pharmaceutical studies and practices
- Lymphoma Diagnosis and Treatment
- Blood Coagulation and Thrombosis Mechanisms
- Cardiac Valve Diseases and Treatments
- Economic and Financial Impacts of Cancer
- Biosimilars and Bioanalytical Methods
- Lung Cancer Treatments and Mutations
- Chronic Myeloid Leukemia Treatments
- Chronic Lymphocytic Leukemia Research
- Meta-analysis and systematic reviews
- Cardiac Arrhythmias and Treatments
- Cancer Treatment and Pharmacology
- Hepatitis C virus research
- Coronary Interventions and Diagnostics
- Antiplatelet Therapy and Cardiovascular Diseases
- Cancer Immunotherapy and Biomarkers
- Cardiac electrophysiology and arrhythmias
- Inflammatory Bowel Disease
- Antibiotics Pharmacokinetics and Efficacy
- CAR-T cell therapy research
Agenzia Regionale di Sanità della Toscana
2016-2025
Regione Toscana
2010-2025
Ospedale Santa Chiara
2022-2024
AULSS 2 Marca Trevigiana
2022-2024
University of Padua
2022-2024
University of Milan
1987-2024
Ospedale di Mirano
2024
Opera del Vocabolario Italiano
2024
Regional Health
2011-2023
Fondazione Toscana Gabriele Monasterio
2023
Background: In the group of inflammatory bowel disease (IBD), ulcerative colitis (UC) and Crohn's (CD) are considered to be more frequent in Western countries areas with a high socioeconomic development but relatively infrequent southern Europe. Sporadic reports have indicated lower incidence milder course Mediterranean countries. Although conclusive data on this point still lacking, recent suggest an increase both prevalence rates. Methods: The UC CD during period January 1978 December 1992...
Journal Article Primary cutaneous follicular centre‐cell lymphoma—a lymphoproliferative disease with favourable prognosis Get access N. PIMPINELLI, PIMPINELLI Clinica Dermatologica II, Universita'degli Studi di Firenze, Italy Dr. N.Pimpinelli, via della Pergola 58, I‐50121, Search for other works by this author on: Oxford Academic Google Scholar M. SANTUCCI, SANTUCCI Istituto Anatomia e Istologio Patologica, A. BOSI, BOSI and Cattedra Divisione Ematologia, S. MORETTI, MORETTI C. VALLECCHI,...
Single‐dose kinetics of 4 Factor VIII concentrates (Kryobulin, Hemofil T, Koate, cryoprecipitate) were studied in 41 patients with haemophilia‐A. Model‐independent methods adopted for calculating the kinetic parameters (area under curve, clearance, area moment mean residence time, volume distribution at steady‐state). No substantial difference was observed characteristics concentrates. A considerable interindividual variability calculated demonstrated all Our findings support need to...
Introduction In conducting a survival meta-analysis, the typical methodological approach analyses hazard ratios (HRs) of individual trials and then combines them into pooled meta-analytical estimate. The length follow-up is not generally accounted for. Recent techniques aimed at patient-data reconstruction from Kaplan-Meier graphs represent an important innovation. These permit combination curves published in single clinical trial but are also applicable to more than one trial. case multiple...
Background: In unresectable pleural mesothelioma, pemetrexed+cisplatin as first line is considered the standard of care, but novel treatments have been recently proposed. Methods: Our objective was to compare, albeit indirectly, results randomized controlled trials on overall survival (OS) The IPDfromKM method employed for reconstruct individual patient data (IPD) from graphs Kaplan-Meier curves. Cox statistics run estimate hazard ratios (HRs). Results: After a literature search Medline (via...
The IPDfromKM method, or Shiny is an artificial intelligence tool that enables indirect comparisons between studies by reconstructing individual patient data (IPD) from Kaplan–Meier (KM) curves. method generally used for superiority analyses, but a further application could be represented non-inferiority analyses. However, there are no supporting this methodological hypothesis. aim of work was to validate the analyses “exploiting” well-described implantable devices occluding left atrial...
Abstract The present publication aims to illustrate key aspects of the modelling work underlying operational design Otway Shallow Fault research project. objective this project is provide a field demonstration interaction between CO2 and faults in subsurface through injection limited volume Port Campbell Limestone aquifer at International Test Centre (Victoria, Australia). An extensive study was conducted for targeting project, facing challenging conditions posed by shallow depth formation...
Abstract Background Paroxysmal atrial fibrillation (PAF) is commonly treated with pharmacological therapies, but these may be insufficient for symptom control. Radiofrequency and cryoballoon ablation have emerged as alternative strategies. This study aimed to compare the efficacy of ablation, radiofrequency anti‐arrhythmic drugs initial therapies symptomatic PAF based on randomized trial data. Methods Data were extracted from trials, individual patient data reconstructed Kaplan–Meier curves...