A5100646411- Catalytic C–H Functionalization Methods
- Organoboron and organosilicon chemistry
- Cyclopropane Reaction Mechanisms
- Catalytic Cross-Coupling Reactions
- Sulfur-Based Synthesis Techniques
- Oxidative Organic Chemistry Reactions
- Synthesis of Indole Derivatives
- Chemical Synthesis and Reactions
- Radical Photochemical Reactions
- Catalytic Alkyne Reactions
- Carbohydrate Chemistry and Synthesis
- Photopolymerization techniques and applications
- Synthesis and Catalytic Reactions
- Organic Light-Emitting Diodes Research
- Synthetic Organic Chemistry Methods
- Asymmetric Hydrogenation and Catalysis
- Biochemical and Molecular Research
- Chemical Synthesis and Analysis
- Synthesis and biological activity
- Axial and Atropisomeric Chirality Synthesis
Nanchang Institute of Technology
2022
Yantai University
2021
Xi'an Jiaotong University
2021
Dalian University
2017-2019
Dalian University of Technology
2017-2019
Chinese Academy of Sciences
2018
Lanzhou Institute of Chemical Physics
2018
Qingdao University
2018
China Three Gorges University
2017
Shenyang Pharmaceutical University
2015-2016
This work describes the first enantioselective 1,6-additions of azlactones to para-quinone methides. In presence a chiral phosphoric acid, 1,6-adducts were obtained in high yields (up 96%) with excellent diastereoselectivities and enantioselectivities (all >20:1 diastereoselectivity ratio (dr), up 99% enantiomeric excess (ee)). Importantly, method offers facile synthetic approach, not only enantiopure α,α-disubstituted α-amino acid esters, but also unnatural enantioenriched...
An efficient approach for the synthesis of azonanes via Pd-catalyzed decarboxylative [5 + 4] cycloaddition has been developed. The reactions feature wide functional group tolerance with exclusive regioselectivity.
A unique strategy for the regiospecific synthesis of bicyclic furopyran derivatives has been developed via a gold(I)-catalyzed propargyl-Claisen rearrangement/6-endo-trig cyclization propargyl vinyl ethers. The introduction angle strain into substrates significantly altered reaction's regioselectivity. Insight regioselectivity cycloisomerization was obtained with density functional theory calculations.
The first general iron-catalyzed boration of allylic esters has been developed.
Abstract A new palladium‐catalyzed selective aminomethylation of conjugated 1,3‐dienes with aminals via double C—N bond activation is described. This simple method provides an effective and rapid approach for the synthesis linear α,β‐unsaturated allylic amines perfect regioselectivity. Mechanistic studies disclosed that one palladium catalyst cleaved two distinct to furnish a cascade activation, in which 1,3‐diamine 1,2‐diamine were initially formed as key intermediates through aminal amine...
An efficient approach to cyclopropylboronates with excellent stereoselectivities <italic>via</italic> iron-catalyzed boration/cyclopropylation of cinnamyl carbonates is developed.
An efficient approach to the synthesis of guaiazulenyl C3-functionalized indoles with excellent regioselectivities via Brønsted acid catalyzed arylation 2-indolylmethanols is developed.
Bisbenzothienyl iridium(III) complexes, [Ir(bt) 2 (PR 3 )]X (bt: 2-phenylbenzo[ d]thiazole, R = n-Bu or Ph, X OTf, BF 4 SbF 6 ) are reported, two of which, (R OTf), have been characterised by X-ray crystallography. The complexes thermally stable and their photophysical properties presented, together with catalytic activity in the “borrowing hydrogen reaction” alcohols amines.
A method for the synthesis of allylboronates by iron-catalyzed boration allylic alcohols with H3BO3 as an additive is developed. The introduction promotes cleavage C‒O bond in obviously. Functional groups, such fluoro, chloro, bromo, alkyl, and alkoxy, are tolerated well. Thus, various obtained acceptable yield.
The currently reported synthesis methods of carbazole-1-formaldehyde or carbazole-1,8-diformaldehyde have some drawbacks, such as long synthetic steps with low yield, high toxicity reagents, risk operation, which affected the progress and application subsequent derivatives.In this work, 9-NH bromocarbazole was protected by 2-(trimethylsilyl)ethoxymethyl chloride (SEMCl), formylation successfully accomplished n-butyllithium/N,N-dimethylformamide (DMF) instead tert-butyllithium/DMF to reduce...