Background A single dose of intraperitoneal (IP) meropenem is recommended for peritoneal-dialysis (PD)-related peritonitis stemming from extended-spectrum β-lactamase-producing organisms. However, data on IP limited. Methods This prospective, descriptive study was conducted to examine plasma and dialysate levels during continuous administration in five patients with PD-related peritonitis. All received an loading 500 mg, followed by at 125 mg/L, four exchanges daily. The concentrations were...

PURPOSE The use of short hydration (SH) to prevent cisplatin-induced nephrotoxicity lacks substantive prospective evaluation. aim this study was evaluate the safety and efficacy SH, including those with head neck cancer (HNC) who are at higher risks mucositis that causes diminished oral intake. METHODS This phase II randomized noncomparative trial included patients were scheduled receive high-dose cisplatin (≥60 mg/m 2 ) in combination another chemotherapy or concurrently radiotherapy....

Chronic kidney disease (CKD) involves inflammation, oxidative stress, and fibrosis, leading to renal dysfunction. Dapagliflozin, an SGLT2 inhibitor, shows renoprotective effects beyond glucose control, but its precise molecular mechanisms remain unclear. This study utilizes network pharmacology docking elucidate multi-target in CKD. Dapagliflozin’s SMILES structure was analyzed for ADMET properties. Potential targets were identified via SwissTargetPrediction, GeneCards, SEA, common...

Objectives Home haemodialysis (HD) and peritoneal dialysis (PD) have seen growth in utilisation around the globe over last few years. However, home dialysis, with its attendant technical complexity risk of adverse events continues to pose challenges for wider adoption. We examined whether differences patients’ learning styles are associated differing both HD PD patients. Design Retrospective cohort study. Setting Tertiary care hospital Toronto, Ontario, Canada. Participants One hundred...

ISPD recommends culture-negative peritonitis in each peritoneal dialysis (PD) center should less than 15%. The hospital Thailand, however faced a significantly high rate of culture negative peritonitis, even using blood bottles technique. This study evaluates the performance three different methods detecting organisms PD related peritonitis.A prospective cohort diagnostic was performed patients diagnosed with Surin Hospital from October 2018 to June 2020. Diagnosis followed guidelines. PDF...

Abstract The prevalence of end-stage renal disease (ESRD) is on the rise worldwide. Meanwhile, number older people requiring dialysis therapy increasing as a result this population. We found that starting in an unplanned manner common occurrence, even for patients with nephrology follow-up. Most centers choose hemodialysis high rate central venous catheter use at time initiation dialysis. Current data has independently associated increased mortality and bacteremia rates. Peritoneal one...

Bowel perforation is a rare but serious complication after peritoneal dialysis (PD) catheter insertion, which significantly increases mortality. Currently, there no recommendation for preferring insertion technique, since neither open surgical or percutaneous technique demonstrate superior outcome.This 78-year-old man who developed jejunal during PD placement, presenting with initial clear and satisfying fluid drainage. was recognized long dwell of returned in yellowish color. Operative...

The effectiveness of tixagevimab-cilgavimab as pre-exposure prophylaxis (PrEP) against breakthrough coronavirus disease 2019 (COVID-19) in dialysis patients remains uncertain due to limited data.

Antiglomerular basement membrane disease (anti-GBM) is an unusual cause of glomerulonephritis. Patients usually present with rapidly progressive glomerulonephritis or without pulmonary hemorrhage. The diagnosis based on linear deposits IgG along the GBM and presence anti-GBM antibodies. However, cases atypical in which antibody was not detected have been reported. We report a 29-year-old pregnant woman underlying systemic lupus erythematosus (SLE) who presented severe due to antiglomerular...

Abstract Introduction The provision of sufficient support contributes to home hemodialysis (HHD) technique survival. need for back‐up treatment in incident and prevalent patients on HHD has not been well described previously, is important from both survival resource allocation. We aimed quantify the amount given our unit, hypothesized that HD facilitated Methods This was a retrospective, single‐center cohort study quantifying between January December 2018. Electronic paper medical records...

There is currently a controversy for the optimal vascular access option in elderly, regarding their multiple comorbidities and life expectancies. Our study aimed to compare survival of tunneled cuff venous catheter (CVC) arteriovenous (AV access) elderly patients.A retrospective cohort was performed by electronic medical record review. All hemodialysis patients aged 65 years over who firstly initiated dialysis from January 1, 2012 December 31, 2016 at Siriraj hospital, Thailand, were...

However, few studies have dealt with the association between BMI and mortality among patients undergoing peritoneal dialysis (PD) even fewer focused on Asian PD patients.The reported were often non-conclusive some yielded contradictory results.This paper, to our best knowledge, registers first attempt systematically review current literature summarize new results population.METHODS: A systematic was performed in Medline EMBASE identify relevant cohort all-cause cardiovascular disease (CVD)...

Abstract Background Patients with End-Stage Renal Disease (ESRD) are at an increased risk for restrictive lung disease due to accumulation of uremic toxins and volume overload. Hemodialysis is the preferred treatment improving function in dialysis patients. However, effects fluid removal solute clearance by hemodialysis on remain unclear. Case presentation We report a case disorder patient, who showed improvement both clinical spirometric after initiation intensive home (32 h per week)....

Objective: High sodium intake is a worldwide problem and contributes to high blood pressure target organ damage. Measurement of 24-hour urine excretion gold standard for evaluation but it difficult practice. In this study, the correlation between spot sodium: creatinine ratio from second void (AM), before dinner (PM), bedtime (HS) 24-hr samples with were evaluated. Methods: The participants recruited single hospital. Participants age > 20 years, eGFR 60 ml/min/1.73 m2 no history diuretics...

Background: Recipient glomerular filtration rate (r-GFR) after living kidney transplantation (KT) is influenced by many factors. Optimal r-GFR varied among different recipient-donor pairs. The defining of “appropriate level” post KT challenging and helpful in clinical practice. aim this study to establish a predictive model estimate the optimal KT. Methods: We examined data all donors recipients performed at our institution between January 2000 December 2011. Recipients with delayed graft...

Background: Recipient glomerular filtration rate (r-GFR) after living kidney transplantation (KT) is influenced by many factors. Optimal r-GFR varied among different recipient-donor pairs. The defining of “appropriate level” post KT challenging and helpful in clinical practice. aim this study to establish a predictive model estimate the optimal KT. Methods: We examined data all donors recipients performed at our institution between January 2000 December 2011. Recipients with delayed graft...