About
Contact & Profiles
A5041736974
Research Areas
- Phagocytosis and Immune Regulation
- Erythrocyte Function and Pathophysiology
- Virus-based gene therapy research
- SARS-CoV-2 and COVID-19 Research
- Protein Kinase Regulation and GTPase Signaling
- RNA Interference and Gene Delivery
- Immune cells in cancer
- Glycosylation and Glycoproteins Research
- Pancreatic function and diabetes
- Extracellular vesicles in disease
- Lipid Membrane Structure and Behavior
- RNA regulation and disease
- Advanced Proteomics Techniques and Applications
- Blood properties and coagulation
University of Pennsylvania
2012-2016
California University of Pennsylvania
2012
10.1182/blood-2014-06-585299
article
EN
Blood
2014-11-20
Lentiviruses infect many cell types and are now widely used for gene delivery in vitro, but vivo uptake of these foreign vectors by macrophages is a limitation. Lentivectors produced here from packaging cells that overexpress "Marker Self" CD47, which inhibits macrophage when prophagocytic factors also displayed. Single particle analyses show "hCD47-Lenti" display properly oriented human-CD47 interactions with the macrophage's inhibitory receptor SIRPA. Macrophages derived human...
10.1038/mtm.2016.80
article
EN
cc-by-nc-nd
Molecular Therapy — Methods & Clinical Development
2016-01-01
10.1016/j.bpj.2014.11.996
article
EN
publisher-specific-oa
Biophysical Journal
2015-01-01
10.1016/j.bpj.2012.11.2321
article
EN
publisher-specific-oa
Biophysical Journal
2013-01-01
10.1016/j.bpj.2012.11.2651
article
EN
publisher-specific-oa
Biophysical Journal
2013-01-01
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