A5028437419- Asymmetric Synthesis and Catalysis
- Synthetic Organic Chemistry Methods
- Chemical Synthesis and Analysis
- Synthesis and Catalytic Reactions
- Marine Sponges and Natural Products
- Click Chemistry and Applications
- Sulfur-Based Synthesis Techniques
- Phosphorus compounds and reactions
- Advanced Synthetic Organic Chemistry
- Organic and Inorganic Chemical Reactions
Palacký University Olomouc
2022-2024
ESPCI Paris
2023
Université Paris Sciences et Lettres
2023
Centre National de la Recherche Scientifique
2023
The University of Texas at San Antonio
2023
École Polytechnique Fédérale de Lausanne
2023
Johannes Kepler University of Linz
2023
Universidade da Coruña
2023
Czech Academy of Sciences, Institute of Experimental Botany
2022
Heteroaryl sulfonamides are important structural motifs in the medicinal and agrochemical industries. However, their synthesis often relies on use of heteroaryl sulfonyl chlorides, which unstable toxic reagents. Herein, we report a protocol that allows direct oxidative coupling thiols primary amines, readily available inexpensive commodity chemicals. The transformation proceeds under mild reaction conditions yields desired N-alkylated good yields. N-alkyl can be further transformed using...
Abstract In this paper, we present a one‐pot protocol that enables straightforward and selective transformation of alkyl benzothiazol‐2‐yl phenyltetrazol‐2‐yl sulfones acyl chlorides into ketones, E‐olefins, Z‐olefins, even pyrroles. The final product the reaction depends on proper choice workup. Notably, designed for olefin formation allows switch between E‐ Z‐olefin by correct These developed protocols facilitate all compounds under mild conditions, as evidenced synthesis (nitro)‐fatty...
The Julia-Kocienski olefination reaction has become over past 30 years since its discovery one of the key C-C connective methods that is used in late-stage natural product synthesis. proceeds under mild conditions, with wide substrate scope and functional group tolerance, high (E) selectivity. In this review, we discuss from a mechanistic point view disclose features play an important role Finally, aspects newly developed modification reaction, which allows formation both (Z) olefins, same...
Since its discovery, the Julia–Kocienski olefination reaction has over past 30 years become one of key C-C connective methods that is used in late-stage natural product synthesis. The proceeds under mild conditions, with a wide substrate scope and functional group tolerance range high (E) selectivity. In this focused review, we discuss from mechanistic point view disclose features play an important role Finally, aspects newly developed modification reaction, which allows formation both (Z)...
Abstract The enantioselective addition of isoxazolidin-5-ones to the β-carbon allenoates has been carried out by using a novel spirobiindane-based quaternary ammonium salt catalyst. This protocol, which proceeds under classical liquid-solid phase-transfer conditions, gives access unprecedented highly functionalized β2,2-amino acid derivatives with good enantioselectivities and in high yields, further manipulations these products have as well.