A5059968809- SARS-CoV-2 and COVID-19 Research
- Tuberculosis Research and Epidemiology
- Mycobacterium research and diagnosis
- SARS-CoV-2 detection and testing
- Diagnosis and treatment of tuberculosis
- COVID-19 Clinical Research Studies
- Respiratory viral infections research
- COVID-19 diagnosis using AI
- Biosensors and Analytical Detection
- COVID-19 epidemiological studies
- Advanced biosensing and bioanalysis techniques
- Infectious Diseases and Tuberculosis
- Pneumonia and Respiratory Infections
Universidad de Las Américas
2022-2025
Universidad de Extremadura
2024
Objective Tuberculosis (TB) is a major public health concern in Ecuador and Colombia, considering that both countries are high-burden TB settings. Molecular epidemiology crucial to understand the transmission dynamics of Mycobacterium tuberculosis complex (MTBC) identify active clusters regional importance. Methods We studied potential between Colombia through analysis population structure MTBC lineages circulating Ecuadorian province Esmeraldas at border with Colombia. A total 105 strains...
The Mycobacterium tuberculosis complex (MTBC), the causative agent of (TB), remains a significant global health challenge, with an estimated 10.8 million cases diagnosed and 1.25 deaths in 2023, according to WHO. In this context, enhancing TB case detection using more sensitive diagnostic methods is essential. Here, we compared performance two commercial real-time polymerase chain reaction (PCR) kits reference standards smear microscopy, culture, Gene Xpert. By analyzing 402 clinical...
Tuberculosis (TB) is a major public health concern in Ecuador and Peru, both settings of high burden drug resistance TB. Molecular epidemiology tools are important to understand the transmission dynamics Mycobacterium tuberculosis Complex (MTBC) track active clusters regional importance. This study first address TB between Peru through population structure MTBC lineages circulating Ecuadorian border province "El Oro". A total number 56 strains from this for years 2012-2015 were included...
Worldwide, the COVID-19 pandemic caused by SARS-CoV-2 has enormously impacted healthcare systems, especially in low and middle-income countries. Coinfections with respiratory pathogens patients may contribute to worse outcomes. This study identified presence of 12 viral coinfections pneumococcal carriers among individuals infection outpatient community settings Ecuador. From January 2020 November 2021, 215 nasopharyngeal nasal swabs were taken from who reported symptoms or had known exposure...
Infections caused by mycobacteria, including Mycobacterium tuberculosis complex (MTBC) and non-tuberculous mycobacteria (NTM), are a major public health issue worldwide. An accurate diagnosis of mycobacterial species is challenge for surveillance treatment, particularly in high-burden settings usually associated with low- middle-income countries. In this study, we analyzed the clinical performance two commercial PCR kits designed identification differentiation MTBC NTM, available setting...
During the second year of COVID-19 pandemic, use Rapid Diagnosis Antigen Tests (RDAgTs) for SARS-CoV-2 detection has substantially increased as some brands available in market were certified clinical by international regulatory agencies. RDAgTs are a fast and cheap tool surveillance with great potential to improve testing capacities middle- low-income countries compared gold standard RT-qPCR. However, performance been shown vary greatly between commercial available, evaluation studies...
OPINION article Front. Cell. Infect. Microbiol., 07 June 2023Sec. Clinical Microbiology Volume 13 - 2023 | https://doi.org/10.3389/fcimb.2023.1179786