A5006002828- Cleft Lip and Palate Research
- Craniofacial Disorders and Treatments
- Supramolecular Self-Assembly in Materials
- Head and Neck Surgical Oncology
- dental development and anomalies
- Hedgehog Signaling Pathway Studies
- Covalent Organic Framework Applications
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- interferon and immune responses
- Phagocytosis and Immune Regulation
- Heterotopic Ossification and Related Conditions
- Alkaline Phosphatase Research Studies
- Parathyroid Disorders and Treatments
- Cell Adhesion Molecules Research
- Advanced Photocatalysis Techniques
University of Michigan
2018-2023
Incorporating supramolecular assemblies of chromophore amphiphiles into covalent hydrogels creates a reusable, robust host for photocatalysis.
A prolonged increase in proinflammatory cytokines is associated with osteoporotic and autoimmune bone loss and, conversely, anti-inflammatory pathways are protection against loss. Milk fat globule-epidermal growth factor (MFG-E)-8 a glycoprotein that proresolving, regulates apoptotic cell clearance, has been linked to disease skeletal homeostasis. The role of MFG-E8 the young vs. adult skeleton was determined mice deficient (KO). In vivo, trabecular similar MFG-E8KO wild-type (WT) at 6 16...
The secondary palate forms from two lateral primordia called the palatal shelves which form a contact in midline, become adherent at fusing interface (medial edge epithelia, MEE) and subsequently fuse. gene encoding transforming growth factor-ß3 ( Tgfb3 ) is strongly specifically expressed MEE cells. Our previous study suggested that expression controlled via upstream cis-regulatory elements around neighboring Ift43 gene. Another canonical Wnt signaling ß-Catenin responsible for MEE-specific...
Abstract Background: The detection of double-stranded cytosolic DNA by cyclic GMP-AMP synthase (cGAS) leads to activation stimulator interferon genes (STING) and the production type-I (IFN-I) as part host defense mechanism. Recently, 2’3’ guanosine monophosphate-adenosine monophosphate (cGAMP), an endogenous activator STING, has been shown be a promising antitumor agent through innate adaptive immunity. However, mechanism which cGAMP results in tumor-specific T-cell expansion tumor...