A5007538951- Cellular Mechanics and Interactions
- Tissue Engineering and Regenerative Medicine
- Bone Tissue Engineering Materials
- Dental Implant Techniques and Outcomes
- Periodontal Regeneration and Treatments
- Electrospun Nanofibers in Biomedical Applications
National University of Singapore
2023-2024
Southern University of Science and Technology
2023
Titanium (Ti) is now widely used as implant material due to its excellent mechanical properties and superior biocompatibilities, while inert bioactivities might lead insufficient osseointegration, limit performance in dental applications.We introduced a robust simple approach of modifying titanium surfaces with polysaccharide complexes. samples were subjected hydrothermal treatment create uniform porous structure on the surface, followed by coating bioinspired self-assembly polydopamine...
Cellular aging stems from multifaceted intra- and extracellular molecular changes that lead to the gradual deterioration of biological function. Altered matrix (ECM) properties include biochemical, structural, mechanical perturbations direct cellular- tissue-level dysfunction. With recent advancements in high-resolution imaging modalities nanomaterial strategies, importance nanoscale ECM features has come into focus. Here, we provide an updated window micro- nano-scale are altered with age...
Abstract Extracellular matrix (ECM) remodeling of cardiac tissue is a key contributor to age-related cardiovascular disease and dysfunction. Aberrant secretion, structural perturbations, degradation specific ECM components lead significant alterations in properties that disrupt healthy cell homeostasis. These changes are multifaceted, as ligand presentation, including both biochemical architectural aspects, often accompanied by stiffness changes, clouding our understanding how which...