A5007696259- Systemic Lupus Erythematosus Research
- Liver Disease Diagnosis and Treatment
- Systemic Sclerosis and Related Diseases
- Gallbladder and Bile Duct Disorders
- Pancreatitis Pathology and Treatment
- Inflammation biomarkers and pathways
- Microscopic Colitis
- Inflammatory Bowel Disease
- Psoriasis: Treatment and Pathogenesis
- Pancreatic and Hepatic Oncology Research
- Neuroscience of respiration and sleep
- Liver Disease and Transplantation
- T-cell and B-cell Immunology
- Cardiac Imaging and Diagnostics
- Cardiovascular Disease and Adiposity
- Neonatal Respiratory Health Research
- Apelin-related biomedical research
- Liver Diseases and Immunity
- Neonatal and fetal brain pathology
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Atherosclerosis and Cardiovascular Diseases
- Cardiovascular Function and Risk Factors
- Helicobacter pylori-related gastroenterology studies
- Salivary Gland Disorders and Functions
- Diet, Metabolism, and Disease
Carol Davila University of Medicine and Pharmacy
2015-2024
Spitalul Clinic Colentina
2014-2023
Institutul National pentru Sanatatea Mamei si Copilului "Alessandrescu-Rusescu"
2022
Avila University
2021
Société Francophone du Diabète
2014-2017
Clinical Emergency Hospital Bucharest
2013
Centar za Promociju Nauke
2013
Hospital de Santa Maria
2013
University of Crete
2013
Background/Aims: Gastrointestinal bleeding is a significant and potentially lethal event. We aimed to review the efficiency safety of self-assembling peptides for treatment prevention gastrointestinal tract bleeding.Methods: conducted systematic search studies describing endoscopic use or in parallel, independent fashion. The primary outcomes were rates successful initial hemostasis, delayed bleeding, rebleeding. secondary adverse events ease volume gel used.Results: Seventeen analyzed....
Mucosal healing is an important predictor of disease-related outcome in patients with inflammatory bowel disease (IBD) patients, including those clinical remission. However, colonoscopy invasive procedure and many decline repeated endoscopic examinations. We aimed to assess whether noninvasive biomarkers could accurately detect mucosal activity IBD remission.We conducted a prospective observational cohort study on remission at Colentina Hospital, Bucharest. Clinical was assessed using the...
Endocan is a marker of angiogenesis previously studied in various types cancer and inflammatory conditions. Its expression influenced by vascular endothelial growth factor A (VEGF A) tumor necrosis alpha (TNF alpha), cytokines involved pathogenetic pathways bowel disease (IBD). The aim this study was to determine whether serum endocan levels were increased IBD patients.We conducted an exploratory pilot study. Serum determined group 33 consecutive patients from observational cohort ongoing at...
BACKGROUND : Optimal training strategies in endoscopic retrograde cholangiopancreatography (ERCP) remain controversial despite the shift toward competence-based models, with limited data available on patient safety during training. We aimed to assess whether pre-procedural clinical predictors could identify patients at low risk of developing procedure-related adverse-events (AEs) a environment. METHODS performed prospective, multicenter, cohort study five centers. A collection system...
Increased atherosclerosis prevalence in patients with systemic lupus erythematosus (SLE) is an epidemiological certainty. SLE are linked to endothelial immune conflict, chronic inflammation antiphospholipid antibodies, and high serum annexin A5 levels. Many of these factors belong the inflammatory cascade which common both ATS. Therefore, there overlap between traditional nontraditional risk patients. The purpose study was determine association conventional cardiovascular characteristics...
Systemic sclerosis (Ssc) is an autoimmune disease characterized by vascular alterations of small arteries and microvessels with subsequent tissue fibrosis. Endocan expressed endothelial cells associated dysfunction; therefore it could be a potential biomarker for Ssc patients.Twenty-one patients 20 sex- age-matched healthy controls were recruited the study. Serum endocan levels determined using ELISA method in all controls.Serum superior (median 2.53 (1.10-7 ng/ml)) compared (0.79 (0-2...
Background . Obesity prevalence is increasing in children. It associated with various comorbidities including nonalcoholic fatty liver disease (NAFLD). Hsp90 isoforms were identified previous proteomic studies as potential biomarkers for NAFLD. The aim of the study was to analyze circulating levels α and β overweight obese In addition, evaluated NAFLD Methods 68 children ten age- gender-matched controls recruited. analyzed from serum both by ELISA. Results Serum total statistically...
Abstract Background. Systemic sclerosis (Ssc) is an autoimmune disease characterized by cutaneous and visceral fibrosis its pathogenesis incompletely understood. T helper cells are key regulators of the immune response they seem to be involved in Ssc clinical manifestations. The aim study determine cytokines secreted Th1 (IFN-γ), Th2 (IL-6) Th17 (IL-17) patients correlate them with specific manifestations patients. Material methods. 35 consecutive 20 age sex matched controls were recruited....
Previous studies reported higher interleukin-6 (IL-6) levels in systemic lupus erythematosus (SLE) patients than healthy controls. However, the clinical relevance of IL-6 SLE has not been clearly established. The present study aimed to evaluate significance serum and urinary their usefulness as markers disease activity SLE. 63 were included. Disease was assessed according Systemic Lupus Activity Measure (SLAM) score. Serum by ELISA. included Romanian patients, female male ratio 9.5:1 with a...
Abstract Background and study aims Current data show that traditional training methods in endoscopic retrograde cholangiopancreatography (ERCP) fall short of producing competent trainees. We aimed to evaluate whether a novel approach simulator-based might improve the learning curve for novice endoscopists ERCP. Methods conducted multicenter, randomized controlled trial using validated mechanical simulator (the Boškoski-Costamagna trainer). Trainees with no experience ERCP received either...
Introduction: The emerging Coronavirus Disease (COVID-19) pandemic caused by Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a serious public health issue due to its rapid spreading, high mortality rate and lack of specific treatment. Given unpredictable clinical course, risk assessment, stratification for severity COVID-19 are required. Apart from serving as admission criteria, prognostic factors might guide future therapeutic strategies. Aim: We aimed compare features...
Abstract Background . Shared decision making (SDM) is becoming more and important for the patient-physician interaction. There has not been a study in Romania evaluating patients’ point of view SDM process yet. Therefore, present aims to evaluate psychometric parameters translated Romanian version SDM-Q-9. Material methods A multicentric cross-sectional was performed comprising eight recruitment centers. The sample consisted in- outpatients who referred Hospital Units treatment atrial...
Introduction: Birth Asphyxia is a severe condition that includes many potential pathways of occurrence both in utero and during childbirth. We aimed to identify describe specific macroscopic microscopic placental injuries birth asphyxia serve as quick tool stratify newborn’s further evolution, hypoxic-ischemic encephalopathy can be responsible for neonatal death or neurologic sequelae compromising the affected persons’ quality life. Materials methods: conducted an observational prospective...
The aim of this study is to assess the lipid profile pattern pediatric overweight and/or obese patients with Non-Alcoholic Fatty Liver Disease (NAFLD) in relation IDF Consensus Criteria for Metabolic Syndrome (MetS).We conducted a cross-sectional preliminary on 45 consecutive patients. Overweight or children aged from 3 18 years were included. Standardized measurement blood pressure and anthropometric parameters performed. Biological evaluation included inflammatory status, profile, glycemic...
Abstract Background Shared decision making (SDM) is very important from patients' perspective. This process has not yet been evaluated in Romania. The study aims to evaluate SDM the perspective and characteristics that associate with SDM. Material methods A cross‐sectional multicentric comprising eight recruitment centres was performed. Inpatients outpatients who referred Hospital Units treating autoimmune diseases or atrial fibrillation were included. Another sample consisted of members...