A5065095737- Long-Term Effects of COVID-19
- COVID-19 Clinical Research Studies
- RNA regulation and disease
- Peripheral Neuropathies and Disorders
- Multiple Sclerosis Research Studies
- Neurological Disorders and Treatments
- Parkinson's Disease Mechanisms and Treatments
- COVID-19 and Mental Health
- Neurological Disease Mechanisms and Treatments
- interferon and immune responses
- Infectious Encephalopathies and Encephalitis
- Pain Mechanisms and Treatments
- Autoimmune Neurological Disorders and Treatments
- Stroke Rehabilitation and Recovery
- SARS-CoV-2 and COVID-19 Research
- Neurological disorders and treatments
- Botulinum Toxin and Related Neurological Disorders
- Alzheimer's disease research and treatments
- Neurology and Historical Studies
- Toxoplasma gondii Research Studies
- Cholinesterase and Neurodegenerative Diseases
- NF-κB Signaling Pathways
- Systemic Sclerosis and Related Diseases
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Functional Brain Connectivity Studies
Spitalul Clinic Colentina
2017-2025
Carol Davila University of Medicine and Pharmacy
2014-2025
Abstract Background and purpose Despite the increasing number of reports on spectrum neurological manifestations COVID‐19 (neuro‐COVID), few studies have assessed short‐ long‐term outcome disease. Methods This is a cohort study enrolling adult patients with neuro‐COVID seen in consultation. Data were collected prospectively or retrospectively European Academy Neurology NEuro‐covid ReGistrY ((ENERGY). The at discharge was measured using modified Rankin Scale defined as ‘stable/improved’ if...
Alzheimer’s disease is a neurodegenerative condition marked by the progressive deterioration of cognitive abilities, memory impairment, and accumulation abnormal proteins, specifically beta-amyloid plaques tau tangles, within brain. Despite extensive research efforts, remains without cure, presenting significant global healthcare challenge. Recently, there has been an increased focus on antibody-based treatments as potentially effective method for dealing with disease. This paper offers...
Background/Objectives: Parkinson’s disease (PD) and hypertension are often coexistent conditions that interact in entwined ways at various levels. Cardiovascular autonomic dysfunction (CAD), a non-motor feature of PD occurring across all stages, alters blood pressure (BP) regulation. Methods: We conducted cross-sectional study enrolling patients with primary hypertension, without diabetes mellitus or other causes secondary CAD, aiming to characterize BP profiles/patterns by ambulatory...
Abstract Background and purpose The aim of this study was to assess the neurological complications SARS‐CoV‐2 infection compare phenotypes outcomes in infected patients with without selected manifestations. Methods data source a registry established by European Academy Neurology during first wave COVID‐19 pandemic. Neurologists collected on seen as in‐ outpatients emergency rooms 23 seven non‐European countries. Prospective retrospective included patient demographics, lifestyle habits,...
Chronic low-grade inflammation and oxidative stress are present in most of the pathologic mechanisms underlying non-communicable diseases. Inflammation redox biomarkers might therefore have a value disease prognosis therapy response. In this context, we performed case-control study for assessing whole blood expression profile redox-related genes elderly subjects with various comorbidities.In 130 pathologies (cardiovascular disease, hypertension, dyslipidemia including hypercholesterolemia,...
Introduction: The emerging Coronavirus Disease (COVID-19) pandemic caused by Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a serious public health issue due to its rapid spreading, high mortality rate and lack of specific treatment. Given unpredictable clinical course, risk assessment, stratification for severity COVID-19 are required. Apart from serving as admission criteria, prognostic factors might guide future therapeutic strategies. Aim: We aimed compare features...
Multiple sclerosis (MS) patients tend to present peculiar personality traits that highly impact their quality of life. Our study aimed determine which are more common in MS compared a sex- and age-matched control group.Patients with relapsing-remitting along group were included. All subjects completed the DECAS Personality Inventory an additional form including demographic characteristics. Data (including descriptive statistics univariate multivariate analysis) analyzed using SPSS.122...
Autoimmune encephalitis is a complex and multifaceted pathology that involves immune-mediated inflammation of the brain. It characterized by body’s immune system attacking brain tissue, leading to cascade inflammatory processes. What makes autoimmune vast wide range causes, mechanisms, clinical presentations, diagnostic challenges associated with condition. The presentations are broad can mimic other neurological disorders, making it challenging differential diagnosis. This diverse...
The novel coronavirus has generated the Coronavirus Disease 2019 (COVID-19) pandemic, which become new challenge for healthcare systems, since there is no etiological treatment and infectiousness of SARS-CoV2 exceeding expectations.Therefore, various treatments have been tried in an attempt to stop spread virus t o enhance early recovery patients.Hydroxychloroquine, antimalarial drug used decades, one first drugs reduce infectivity virus.First data were promising, but afterwards, adverse...
Cytokine storm seems to be one of the main culprits for developing a severe form COVID-19, IL-6 being its basic components.Therefore, currently, tocilizumab is widely studied as powerful treatment in patients with forms COVID-19.Our aim was determine whether it could potentiate favourable outcome such patients.We conducted retrospective observational study including all consecutive admitted confirmed SARS-CoV-2 infection that received period between 01.05-23.08.2020 "Matei Balș" National...
(1) Background: Emerging evidence indicates that non-motor symptoms significantly influence the quality of life in dystonic patients. Therefore, it is essential to evaluate their psychological characteristics and personality traits. (2) Methods: Subjects with idiopathic dystonia a matched control group were enrolled this prospective observational cohort study. Inclusion criteria for patient included diagnosis, evolution exceeding 1 year, signed informed consent. lack neurological...
Abstract: Autoimmune encephalitis is a complex and multifaceted pathology that involves the immune-mediated inflammation of brain. It characterized by body's immune system mistakenly attacking brain tissue, leading to cascade inflammatory processes. What makes autoimmune vast wide range causes, mechanisms, clinical presentations, diagnostic challenges associated with condition. The presentations are broad can mimic other neurological disorders, making it challenging differential...
Toxoplasmosis is an ubiquotus infection caused by intracellular parasite with specific tropism for brain and muscle tissue, most frequently encountered in HIV infected patients.Multiple sclerosis the prevalent immune-mediated demyelinating disease of central nervous system, especially young women.The co-occurence these two pathologies immunocompetent patient should not be missed out, as it a requires particular approach regarding treatment.
chronic neurological diseases such as multiple sclerosis (MS) and Parkinson's disease (PD) determines highly social impact through direct indirect cost burden, so that management of quality life(QoL) these patients is often difficult. to assess whether the relantionship between depression relevant in quantifying QoL. proove associated with serious should not be minimized. we followed up 20 (10 MS-mean age 39.1, mainly women 10 PD-mean 55.8, men) during one year after diagnosis depression;...
Introduction Multiple sclerosis (MS) is the most common chronic neurologic disease affecting young people. Cognitive dysfunction an important part of disability, interfering with quality life (QoL). Disease modifying therapies (DMT) are gold standard long-term treatment in MS. Objectives Assessment DMT impact on evolution cognitive dysfunction. Aims To analyze status a lot 74 patients MS, mean age 40.4 years, treated different National Health Program. Methods Testing during 2014–2015 for...
frontotemporal dementia (FTD) is marked by progressive changes in behavior, personality, variable degrees of language impairment and preservation other cognitive domains. neuropsychological assessments must be more attentive performed, as FTD the third cause neurodegenerative dementia, younger ages, being often misdiagnosed. During one year we followed up every 3 months, 4 women, mean age 53.5 years admitted Psychiatry Clinic. They all presented for depressive symptoms, started about before,...
Introduction Ischemic stroke is in increasing incidence, so that long term sequels are of great importance for management quality life and economics issues. Objectives To determine risk factors associated with cognitive disturbances, after ischemic stroke. Aims Assessment social medical outcome disturbances. Methods During 6 months, 268 patients antecedents disturbances installed first year major stroke, were assessed neurology department. We performed neuropsychological tests as mini mental...