A5072413245- Antibiotic Use and Resistance
- Antibiotics Pharmacokinetics and Efficacy
- Antimicrobial Resistance in Staphylococcus
- Breast Cancer Treatment Studies
- Bacterial Identification and Susceptibility Testing
- Cancer Treatment and Pharmacology
- Advanced Breast Cancer Therapies
- CAR-T cell therapy research
- Antibiotic Resistance in Bacteria
- Immunotherapy and Immune Responses
- Innovations in Medical Education
- Streptococcal Infections and Treatments
- Antifungal resistance and susceptibility
- Clostridium difficile and Clostridium perfringens research
- Glioma Diagnosis and Treatment
- Cancer Immunotherapy and Biomarkers
- Pharmaceutical Practices and Patient Outcomes
- Health Systems, Economic Evaluations, Quality of Life
- Drug-Induced Adverse Reactions
- Infective Endocarditis Diagnosis and Management
- Patient Satisfaction in Healthcare
- Diversity and Career in Medicine
- Fungal Infections and Studies
- Education and Critical Thinking Development
- Pneumonia and Respiratory Infections
University of Mississippi
2016-2025
University of Kansas Medical Center
2022-2023
University of Kansas
2022
The University of Kansas Cancer Center
2022
University of Mississippi Medical Center
2017-2022
American College of Clinical Pharmacy
2022
State Street (United States)
2016-2021
Jackson State University
2021
Henry Ford Hospital
2014-2016
Eugene Applebaum College of Pharmacy and Health Sciences
2016
Predictive modeling suggests that actual carbapenem MIC results are more predictive of clinical patient outcomes than categorical classification the as susceptible, intermediate, or resistant. Some have speculated current CLSI guidelines' suggested thresholds too high and success is likely if value ≤1 mg/liter for certain organisms. Patients treated with carbapenems positive blood cultures Pseudomonas aeruginosa, Acinetobacter baumannii, extended-spectrum beta-lactamase (ESBL)-producing...
Abstract Daptomycin use for gram-positive infections has increased. This cost minimization analysis aimed to determine and/or time savings of daptomycin over vancomycin. The estimated hospital was US$166.41 per patient, and pharmacist saved almost 20 minutes patient. the potential save both money.
Abstract Background Staphylococcus aureus can lead to severe infections, including bloodstream which are associated with high mortality. Infective endocarditis (IE) is a concerning complication of S. infections (SABSIs), ruled out by transesophageal echocardiogram (TEE). The COVID-19 pandemic led decrease in TEEs at the University Mississippi Medical Center (UMMC) for patients SABSIs. This study explores impact reduced TEE rates on clinical decisions SABSI patients. Methods retrospective...
Abstract Pharmacists frequently engage in clinical and outcomes‐based research; however, not all pharmacists are knowledgeable about appropriate data analysis methodology, especially concerning the unavoidable challenging problem of missing data. Many studies within pharmacy fail to discuss how were handled, others use techniques that less than optimal, potentially leading biased and/or inefficient findings. Although sophisticated methods can help address data, adoption these is uniform....
Stenotrophomonas maltophilia is a cause of infection most commonly in the opportunistic host. Trimethoprim-sulfamethoxazole and levofloxacin are considered first-line treatment agents. With reports increasing resistance to these agents, it important determine risk factors associated with non-susceptible isolate. This was real-world, multicentre, retrospective case-control study from five centres southeast United States evaluating S. maltophilia. The primary outcome non-susceptibility...
System Pharmacists (ASHP) and the Society of Infectious Diseases (SIDP) jointly believe that all pharmacists have a responsibility to promote antimicrobial stewardship (AMS) optimize use.Pharmacists qualified through education, training, or experience in infectious diseases (ID) and/or AMS should be recognized as appropriate leaders, ideally co-leaders, programs (ASPs).
The purpose of this study was to assess the clinical impact BioFire FilmArray Meningitis/Encephalitis (ME) panel on antimicrobial use and outcomes. This retrospective, quasi-experiment evaluated adult pediatric patients with suspected ME, evidenced by cerebrospinal fluid (CSF) culture. Hospital-acquired meningitis who received antimicrobials >48 h prior lumbar puncture were excluded. primary endpoint days therapy pre- post-implementation ME panel. Secondary endpoints included total length...
Candidemia represents a leading cause of healthcare-associated bloodstream infections with significant morbidity and mortality. Previous studies have demonstrated that comprehensive care bundles improve candidemia management but are time-consuming.To determine the impact one-time targeted intervention on time to initiation adequate therapy compared standard care.This Institutional Review Board (IRB)-approved, quasi-experiment evaluated involving single phone call primary team providing...
Candida species are responsible for 15% of bloodstream infections, leading to prolonged hospitalizations and increased mortality. With the rise in obesity, antifungal dosing is unclear. The purpose this study was determine differences clinical outcomes between obese versus non-obese patients with infections. This retrospective cohort included adult patient's first episode infection treated ≥ 48 h therapy 1 June 2013 31 August 2019. Patients were excluded for: dual systemic therapy,...
The purpose of this study was to determine the incidence and risk factors for surgical site infections in microvascular reconstruction patients with head neck cancer.One hundred seventeen cancer undergoing received postoperative infection prophylaxis were followed 30 days. Surgical categorized by empiric spectrum activity. Risk development cumulative characterized.Thirty-seven developed (cumulative 31.6%). identified logistic regression include alcohol use (odds ratio [OR] = 2.704; 95%...
We sought to define trends in and predictors of carbapenem consumption across community, teaching, university-affiliated hospitals the United States Canada. conducted a retrospective multicenter survey broad-spectrum noncarbapenem beta-lactam between January 2011 December 2013.