Yan Li

ORCID: 0000-0002-6011-7097
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About
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Research Areas
  • Bacterial Identification and Susceptibility Testing
  • Genomics and Phylogenetic Studies
  • Mycobacterium research and diagnosis
  • Non-Invasive Vital Sign Monitoring
  • Heart Rate Variability and Autonomic Control
  • Enterobacteriaceae and Cronobacter Research
  • Antibiotic Resistance in Bacteria
  • Blood Pressure and Hypertension Studies
  • Antibiotic Use and Resistance

Chongqing Emergency Medical Center
2021-2023

Chongqing University
2021-2023

Yueyang Hospital
2021

Shanghai University of Traditional Chinese Medicine
2021

Wuhan University
2020

Renmin Hospital of Wuhan University
2020

Abstract BACKGROUND As approximately 19% of global deaths are attributable to infectious diseases, early diagnosis infection is very important reduce mortality. Traditional detection strategies have limited sensitivity, range, and turnaround times; a technology that can simultaneously detect bacterial fungal infections within 24 h urgently need in clinical settings. METHODS We developed nanopore targeted sequencing (NTS) for same-day simultaneous Diagnosis infections. NTS was by...

10.1101/2020.04.08.20057604 preprint EN medRxiv (Cold Spring Harbor Laboratory) 2020-04-11

Infectious diseases have always been a difficult clinical problem, especially severe infections and those of unknown origin. The invention new detection method is particularly important urgent. Metagenomic next-generation sequencing (mNGS) high-throughput that sequences microbial DNA RNAs from fluid or solid tissue samples in hours. All sequence data present specimen can be used for pathogen identification after series bioinformatics analysis. Recently, mNGS has preclinical trials to find...

10.14218/erhm.2021.00014 article EN Exploratory Research and Hypothesis in Medicine 2021-07-01

Abstract Background: In recent years, carbapenem-resistant hypervirulent Klebsiella pneumoniae (CR-hvKP) has been increasingly reported and poses severe therapeutic challenge to global public health, but not yet systematically studied in elderly patients. This study aimed investigate the clinical molecular characteristics risk factors of CR-hvKP infections Methods: We retrospectively investigated patients with (CRKP) intensive care unit (ICU),between January 2020 December 2020, data being...

10.21203/rs.3.rs-746521/v1 preprint EN cc-by Research Square (Research Square) 2021-08-02
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