Yaojun Lu

ORCID: 0000-0002-6019-2687
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About
Contact & Profiles
Research Areas
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Advanced Glycation End Products research
  • Tryptophan and brain disorders
  • Neuroscience and Neuropharmacology Research
  • Immune Response and Inflammation

Obstetrics and Gynecology Hospital of Fudan University
2019-2023

Microglial inflammation leads to the upregulation of proinflammatory cytokine and enzyme expression, resulting in inflammation-induced neuronal cell apoptosis. Ketamine, an anesthetic mostly used critical patients, has been reported possess neuroprotective effects. However, potential mechanism is still not well understood. In present study, we investigated how ketamine attenuates lipopolysaccharide (LPS)-mediated BV2 inflammation. LPS upregulated increased NF-κB phosphorylation nuclear...

10.1111/fcp.12508 article EN Fundamental and Clinical Pharmacology 2019-09-12
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