- Dialysis and Renal Disease Management
- Renal Diseases and Glomerulopathies
- Gut microbiota and health
- Extracellular vesicles in disease
- Mitochondrial Function and Pathology
- Metabolism and Genetic Disorders
- Neurological Complications and Syndromes
- Renal and Vascular Pathologies
- Autophagy in Disease and Therapy
- Muscle and Compartmental Disorders
- Nonlinear Waves and Solitons
- Healthcare cost, quality, practices
- MRI in cancer diagnosis
- Neuroscience and Neuropharmacology Research
- Mast cells and histamine
- Fractional Differential Equations Solutions
- Pharmacological Effects and Toxicity Studies
- Differential Equations and Boundary Problems
- Sports injuries and prevention
- Inflammatory Myopathies and Dermatomyositis
- Autoimmune Bullous Skin Diseases
- Nonlinear Photonic Systems
- Artificial Intelligence in Healthcare and Education
- Neuroinflammation and Neurodegeneration Mechanisms
- Hip disorders and treatments
Chinese People's Liberation Army
2020-2025
Chinese People’s Liberation Army 263 hospital
2023-2025
Hangzhou Medical College
2019-2023
Zhejiang Provincial People's Hospital
2010-2023
Chinese PLA General Hospital
2019-2022
State Key Laboratory of Kidney Diseases
2020-2022
PLA Academy of Military Science
2021
People's Liberation Army No. 150 Hospital
2021
Shandong Normal University
2021
Huashan Hospital
2019
Chronic kidney disease (CKD) is an important affecting human health, especially in developing countries where CKD has high prevalence and mortality rates.[1] According to the latest epidemiological data, of among Chinese people 8.2%, which 1.8% are patients with stage 5 (known as end-stage renal [ESRD]).[2] Hemodialysis (HD) main treatment for ESRD patients. China National Renal Data System (CNRDS), number receiving HD 2022, was 844,000. Although dialysis can partially replace function...
Microglial inflammation leads to the upregulation of proinflammatory cytokine and enzyme expression, resulting in inflammation-induced neuronal cell apoptosis. Ketamine, an anesthetic mostly used critical patients, has been reported possess neuroprotective effects. However, potential mechanism is still not well understood. In present study, we investigated how ketamine attenuates lipopolysaccharide (LPS)-mediated BV2 inflammation. LPS upregulated increased NF-κB phosphorylation nuclear...
Radiological assessments are considered an important part of the management patellar instability (PI). However, PI measurements influenced by knee position, which cannot be guaranteed to same for each examination. Therefore, we aimed determine reliability common on magnetic resonance imaging (MRI). Two MRI examinations within a 6-month period were obtained from 51 knees. The quantitatively determined and re-evaluated. intraclass correlation coefficients (ICC), Bland–Altman plot, standard...
Abstract Background Patients with both diabetes mellitus (DM) and kidney disease could have diabetic nephropathy (DN) or non-diabetic renal (NDRD). IgA (IgAN) membranous (MN) are the major types of NDRD. No ideal noninvasive diagnostic model exists for differentiating them. Our study sought to construct models these diseases identify biomarkers that can reflect severity prognosis DN. Methods The were constructed using logistic regression analysis validated in an external cohort by receiver...
Abstract Background The infrapatellar fat pad (IFP) may have bilateral influence on knee osteoarthritis (KOA). IFP evaluation be a key contributor to the diagnostic and clinical management of KOA. Few studies evaluated KOA-related alteration with radiomics. We investigated radiomic signature for assessment KOA progression in older adults. Methods A total 164 knees were enrolled grouped based Kellgren-Lawrence (KL) scoring. MRI-based features calculated from segmentation. was developed using...
The composition of the gut microbiota varies among end-stage renal disease (ESRD) patients on basis their mode replacement therapy (RRT), with notably more pronounced dysbiosis in those undergoing hemodialysis (HD). Interventions such as dialysis catheters, unstable hemodynamics, strict dietary restrictions, and pharmacotherapy significantly alter intestinal microenvironment, thus disrupting HD patients. may influence HD-related complications, including cardiovascular (CVD), infections,...
Diabetic nephropathy (DN), as the one of most common complications diabetes, is generally diagnosed based on a longstanding duration, albuminuria, and decreased kidney function. Some patients with comorbidities diabetes other primary renal diseases have similar clinical features to DN, which defined non-diabetic disease (NDRD). It necessary distinguish between DN NDRD, considering they differ in their pathological characteristics, treatment regimes, prognosis. Renal biopsy provides gold...
Discriminating between diabetic nephropathy (DN) and non-diabetic renal disease (NDRD) can help provide more specific treatments. However, there are no ideal biomarkers for their differentiation. Thus, the aim of this study was to identify diagnosing predicting progression DN by investigating different salivary glycopatterns. Lectin microarrays were used screen glycopatterns in patients with or NDRD. The results validated lectin blotting. Logistic regression artificial neural network...
In this paper, abundant interaction solutions for the (1[Formula: see text]+[Formula: text]1)-dimensional generalized Drinfel’d–Sokolov–Wilson (gDSW) equation are presented. First, two groups of lump-soliton-type constructed by using a combination quadratic function and exponential functions. Especially, lump-twin soliton-type solution therein can generate rogue wave, which rarely appears in nonlinear systems comparison with (2[Formula: systems. When certain parameters taken to zero, these...
Objective To discuss the clinical value of digital subtraction angiography(DSA)and interventional therapy in abdominal exsanguinations including intra-abdominal hemorrhage,retroperitoneal hemorrhage and gastrointestinal secondary to surgery.Method From June 2003 2009,a total 24 patients with doubtful underwent DSA examination received therapy.The imaging efficacy were retrospectively analyzed.The hemoglobin,hemtocdt,blood pressure,and heart rate before 3 days after operation compared.The...
This paper studies how to evaluate the performance of commercial banks scientifically.RAROC model is used analyze financial data 16 listed in China for 4 years.Then, this clarifies that RAROC (Risk-adjusted Capital Return Rate) an appropriate index banks.The establishment and application system with as core will help establish restraint incentive mechanism China.
Renal ischemia-reperfusion injury is a postoperative such as kidney transplantation, which has high incidence, complicated and unclear mechanism, there are no effective prevention treatment measures. During renal injury, mitochondria play an important role in the mitochondrial permeability transition pore (mPTP), macromolecular complex that continues to open under stress will cause series of functional disorders mediate tissue damage. Understanding structure function mPTP allow us better...