- Clinical practice guidelines implementation
- Health Systems, Economic Evaluations, Quality of Life
- Chronic Disease Management Strategies
- Primary Care and Health Outcomes
- Health Policy Implementation Science
- Healthcare cost, quality, practices
- Meta-analysis and systematic reviews
- Patient-Provider Communication in Healthcare
- Healthcare Policy and Management
- Palliative Care and End-of-Life Issues
- Healthcare Systems and Technology
- Cancer Treatment and Pharmacology
- Health Promotion and Cardiovascular Prevention
- Patient Satisfaction in Healthcare
- Mental Health and Patient Involvement
- Healthcare Systems and Reforms
- Diabetes Management and Education
- Pain Management and Opioid Use
- Mental Health and Psychiatry
- Delphi Technique in Research
- Healthcare Quality and Management
- Medical Malpractice and Liability Issues
- Ethics in Clinical Research
- Health Sciences Research and Education
- Medical Research and Practices
Maastricht University
2011-2025
Huisarts en Wetenschap
2008-2024
Dutch College of General Practitioners
2014-2024
University Medical Center
2010-2023
Netherlands Institute for Health Services Research
2023
The Hague University of Applied Sciences
2023
Zorginstituut Nederland
2018-2022
Maastricht University Medical Centre
2020-2021
Personalis (United States)
2018
Urban Institute
2015
We undertook research to improve the AGREE instrument, a tool used evaluate guidelines. tested new seven-point scale, evaluated usefulness of original items in investigated evidence support shorter, tailored versions tool, and identified areas for improvement.We report on one component larger study that mixed design with four factors (user type, clinical topic, guideline condition). For analysis reported this article, we asked participants read use it based complete three outcome measures...
We established a program of research to improve the development, reporting and evaluation practice guidelines. assessed construct validity items user's manual in beta version AGREE II.We designed guideline excerpts reflecting high-and low-quality content for 21 23 tool. two study packages so that one high-quality each item were randomly assigned package. 30 participants packages. Participants reviewed rated according instructions completed survey assessing manual.In all cases, be high...
Despite wide distribution and promotion of clinical practice guidelines, adherence among Dutch general practitioners (GPs) is not optimal. To improve to an analysis barriers implementation advocated. Because different recommendations within a guideline can have barriers, in this study we focus on key rather than guidelines as whole, explore the perceived by GPs.A qualitative using six groups was conducted, which 30 GPs participated, with average seven per session. Fifty-six were derived from...
Purpose To describe the quality of oncology guidelines developed in different countries. Methods The Appraisal Guidelines and Research Evaluation (AGREE) Instrument was used to assess 100 (including 32 guidelines) from 13 criteria instrument are grouped into six domains: scope purpose, stakeholder involvement, rigor development, clarity presentation, applicability, editorial independence. Results Oncology had significantly higher scores on development than nononcology (42.2% v 29.4%; P =...
Integration of care is emerging as a central challenge health delivery, particularly for patients with multiple, complex chronic conditions. The authors argue that the concept “integrated patient care” would benefit from further clarification regarding (a) object integration and (b) its essential components, when constructing measures.To address these issues, propose definition integrated distinguishes it delivery organizations, acknowledging organizational structures processes may fail to...
<h3>Importance</h3> Clinical practice guidelines (CPGs) may lack rigor and suitability to the setting in which they are be applied. Methods yield clinical guideline recommendations that credible implementable remain determined. <h3>Objective</h3> To describe development of AGREE-REX (Appraisal Guidelines Research Evaluation–Recommendations Excellence), a tool designed evaluate quality recommendations. <h3>Design, Setting, Participants</h3> A cross-sectional study 322 international...
To describe systematically the structures and working methods of guideline programs.Descriptive survey using a questionnaire with 32 items based on framework derived from literature. Answers were tabulated checked by participants.Key informants 18 prominent organizations in United States, Canada, Australia, New Zealand, nine European countries.History, aims, methodology, products deliveries, implementation, evaluation, procedure for updating guidelines, future plans.Most programs established...
<h3>Background</h3> Developing and updating high-quality guidelines requires substantial time resources. To reduce duplication of effort enhance efficiency, we developed a process for guideline adaptation assessed initial perceptions its feasibility usefulness. <h3>Methods</h3> Based on preliminary developments empirical studies, series meetings with experts were organised to define (ADAPTE) develop manual toolkit made available website (http://www.adapte.org). Potential users, developers...
Despite considerable efforts to promote and support guideline use, adherence is often suboptimal. Barriers vary not only across guidelines but also recommendations within guidelines. The aim of this study was assess the perceived barriers among GPs by focusing on key We conducted a cross-sectional electronic survey 703 in Netherlands. Sixteen were derived from four national Six statements included address attitudes towards general. In addition, asked rate their (one statement) (fourteen...
OBJECTIVE—To compare guidelines on diabetes from different countries in order to examine whether differences recommendations could be explained by use of research evidence. RESEARCH DESIGN AND METHODS—We analyzed 15 clinical type 2 13 using qualitative methods the and bibliometric measure extent overlap citations used guidelines. A further analysis cited evidence for two specific issues care explored apparent discrepancy between RESULTS—The made were agreement about general management...
<h3>Background</h3> Clinical practice guidelines (CPG) are important tools for improving patient care. Patient and public involvement is recognised as an essential component of CPG development implementation. The Guideline International Network Public Involvement Working Group (G-I-N PUBLIC) aims to support the development, implementation evaluation guideline-oriented programmes (PPIPs). <h3>Objective</h3> To develop international research agenda on in CPG. <h3>Method</h3> 56 developers,...
Background. The role of patient and public involvement programs (PPIPs) in developing implementing clinical practice guidelines (CPGs) has generated great interest. Purpose. authors sought to identify key components PPIPs used CPGs. Data sources. searched bibliographic databases contacted relevant organizations. Study selection. In total, 2161 articles reports were retrieved on the development implementation Of these, 71 qualified for inclusion review. extraction. Reviewers independently...
We aimed to assess and characterize sex differences in adverse drug reactions (ADRs) reported the national pharmacovigilance centre Netherlands while considering use.ADRs spontaneously by healthcare professionals patients Lareb were used. Drug-ADR combinations at least 10 times between 2003-2016 for drugs used ≥10,000 persons that period included. Data about number of users was obtained from National Health Care Institute. Sex-specific ADRs, like gynaecological problems, excluded. Sex...
Context In the past 50 years, individual patient involvement at clinical consultation level has received considerable attention. More recently, patients and public have increasingly been involved in collective decisions concerning improvement of health care policymaking. However, rigorous evaluation guiding development implementation effective interventions is lacking. This article describes those key ingredients likely to affect members’ ability deliberate productively with professionals...