- Phase Equilibria and Thermodynamics
- Advancements in Transdermal Drug Delivery
- Essential Oils and Antimicrobial Activity
- Plant chemical constituents analysis
- Advanced Drug Delivery Systems
- Phytochemical compounds biological activities
- Natural product bioactivities and synthesis
- Pharmacological Receptor Mechanisms and Effects
- Synthesis and pharmacology of benzodiazepine derivatives
- Synthesis of Organic Compounds
- Curcumin's Biomedical Applications
- Advanced Chemical Sensor Technologies
- Photodynamic Therapy Research Studies
- Microbial Inactivation Methods
- Bioactive Compounds and Antitumor Agents
- Carbon Dioxide Capture Technologies
- Advanced Thermodynamics and Statistical Mechanics
- Meat and Animal Product Quality
- Drug Solubulity and Delivery Systems
- Receptor Mechanisms and Signaling
- Nanocomposite Films for Food Packaging
- Microfluidic and Capillary Electrophoresis Applications
- Sesquiterpenes and Asteraceae Studies
Universidade Federal da Bahia
2008-2016
University of Padua
2015
Fundação Oswaldo Cruz
2010
Universidade do Porto
2008-2009
Zanthoxylum tinguassuiba essential oil (ZtEO) contains α-bisabolol, a known antiglioma sesquiterpene, among other potentially active substances. Medical applications of this require advances in the design distinctive carriers due to its low water solubility and easy degradation by heat, light, oxygen. The aim work was evaluate enhancement oxidative stability ability reduce glioblastoma cell viability ZtEO loaded into liposomes. Multi- unilamellar vesicles were prepared carry ZtEO. By using...
The interest of the pharmaceutical industry in lipid drug delivery systems due to their prolonged release profile, biocompatibility, reduction side effects, and so on is already known. However, conventional methods preparation these structures for use production are difficult since usually multi-step involve high amount organic solvent. Furthermore, some processes need extreme conditions, which can lead an increase heterogeneity particle size degradation drug. An alternative system...
Opioids have been used as the reference treatment on chronic pain. However, they are related to serious adverse effects which affect patient compliance treatment, well as, his quality of life. Particulate formulations investigated an alternative improve opioid efficacy and safety.Summarise available studies concerning micro nanoencapsulated discussing their biopharmaceutical characteristics, such composition, size, in vitro release, pharmacokinetic antinociceptive profile.Papers 1995-2015 at...
Rutaceae is a taxon with species very well distributed in Brazilian semi-arid area, commonly used folk medicine. Species from this genus have diverse biological activity described literature. In work, immunomodulatory and bactericidal are for chloroform ethyl acetate extracts of three them (Esenbeckia grandiflora Mart., Pilocarpus spicatus A.St.-Hil. Galipea simplicifolia Schult.). Initially all the samples had their cytotoxicity evaluated, aiming to determine LC50. The potential was...
Abstract A reversed‐phase high performance liquid chromatography method has been developed and validated for determination quantitation of the natural sesquiterpene (−)‐ α ‐bisabolol. Furthermore application was done by characterization chitosan milispheres liposomes entrapping Zanthoxylum tingoassuiba essential oil, which contains appreciable amount C 18 column gradient elution used with mobile phase composed (A) acetonitrile–water–phosphoric acid (19:80:1) (B) acetonitrile. The eluent...