A5024593436- Salmonella and Campylobacter epidemiology
- Vibrio bacteria research studies
- Viral gastroenteritis research and epidemiology
- Listeria monocytogenes in Food Safety
- Food Safety and Hygiene
- Animal Nutrition and Physiology
- Aquaculture disease management and microbiota
- Bacteriophages and microbial interactions
- Meat and Animal Product Quality
- Probiotics and Fermented Foods
- Identification and Quantification in Food
- Antibiotic Resistance in Bacteria
- Bacterial biofilms and quorum sensing
- Cancer Research and Treatments
- Yersinia bacterium, plague, ectoparasites research
- Immune Response and Inflammation
- Leptospirosis research and findings
- Veterinary medicine and infectious diseases
- Glycosylation and Glycoproteins Research
- Pharmaceutical and Antibiotic Environmental Impacts
- Escherichia coli research studies
- Essential Oils and Antimicrobial Activity
- Child Nutrition and Water Access
- Microbial Inactivation Methods
- Vitamin C and Antioxidants Research
Freie Universität Berlin
2016-2025
Institut für Hygiene und Umwelt
2021-2022
Ufa Research Institute of Occupational Health and Human Ecology
2019
Federal Institute for Risk Assessment
2006-2011
Leipzig University
2001-2007
Abstract Background Campylobacter jejuni and coli are human intestinal pathogens of global importance. Zoonotic transmission from livestock animals or animal-derived food is the likely cause for most these infections. However, little known about their general host-specific mechanisms colonization, virulence pathogenicity factors. In certain hosts, species colonize persistently do not disease, while they acute disease in humans. Results Here, we investigate putative host-specificity using...
The 2011 EFSA opinion on Campylobacter was updated using more recent scientific data. relative risk reduction in EU human campylobacteriosis attributable to broiler meat estimated for on-farm control options Population Attributable Fractions (PAF) interventions that reduce flock prevalence, updating the modelling approach caecal concentrations and reviewing literature. According PAF analyses calculated six options, mean reductions could be achieved by adoption of each these individually are...
Campylobacter infection is the most commonly notified bacterial enteritis in Germany. We performed a large combined case-control and source attribution study (Nov 2011-Feb 2014) to identify risk factors for sporadic intestinal infections determine relative importance of various animal sources human conducted multivariable logistic regression analysis factors. Source was using asymmetric island model based on MLST data animal/food isolates. As we considered chicken, pig, pet dog or cat,...
Vibrio identification by means of traditional microbiological methods is time consuming because the many biochemical tests that have to be performed distinguish closely related species. This work aimed at evaluating use MALDI-TOF mass spectrometry for rapid (V.) spp. as an advantageous application rapidly discriminate most important and from bacterial species like Photobacterium damselae Grimontia hollisae other aquatic bacteria Aeromonas spp.Starting sub-colony amounts pure cultures grown...
Bacteriophage treatment is a promising tool to reduce Campylobacter in chickens. Several studies have been published where group II or III phages were successfully applied. However, these two groups of are different regarding their host ranges and cell receptors. Therefore, concerted activity might enhance the efficacy decrease number resistant bacteria.In this study we compared lytic properties some analysed suitability various for reduction C. jejuni broiler We show that exhibit kinetics...
Aims The pathogenic potential of Arcobacter butzleri isolates was investigated by detecting the presence putative virulence genes and analysing adhesive invasive capabilities in cell cultures human lines. Methods Results ten 52 A. determined PCR. ciaB, mviN, pldA, tlyA, cj1349 cadF were detected all, whilst irgA (15%), iroE (60%), hecB (44%) hecA (13%) only few isolates. On HT-29 cells, four six adhered to three them able invade, all invaded Caco-2 cells with higher degrees. sequenced, but...
Global ocean warming results in an increase of infectious diseases including elevated emergence Vibrio spp. Northern Europe. The European Centre for Disease Prevention and Control reported annual periods high to very risks infection with during summer months along the North Sea Baltic coasts. Based on those facts, risk infections associated recreational bathing coastal waters increases. To obtain overview seasonal spatial distribution potentially human pathogenic at German coasts, this study...
Non-O1/non-O139 Vibrio cholerae (NOVC) are ubiquitous in aquatic ecosystems. In rare cases, they can cause intestinal and extra-intestinal infections human. This ability is associated with various virulence factors. The presence of NOVC German North Sea Baltic was observed previous studies. However, data on characteristics still scarce. Therefore, this work aimed to investigating the potential isolated these two regions. total, 31 strains were collected subjected whole genome sequencing....
We have sampled 146 German broiler flocks at slaughter from May 2004 to April 2005 determine the prevalence of Campylobacter spp. and investigate risk factors for presence flock level. Cecal samples were tested in accordance ISO 10727, potential analyzed using farm- flock-specific information obtained questionnaires. Of tested, 44% Campylobacter-positive, most infected with jejuni. Higher was found during months October (52%). Using questionnaires, we identified 3 colonization. significantly...
Carbapenems belong to the group of last resort antibiotics in human medicine. Therefore, emergence growing numbers carbapenemase-producing bacteria food-producing animals or environment is worrying and an important concern for public health sector. In present study, a set 45 Enterobacteriaceae isolated from German retail seafood (clams shrimps), sampled 2016, were investigated by real-time PCR presence bacteria. One Escherichia coli (ST10), Venus clam (Ruditapes philippinarum) harvested...
Antimicrobial resistance was determined for 341 thermophilic Campylobacter jejuni isolates obtained from human clinical cases (n = 101), broiler products 98), dairy cattle 41) and wild birds 101) with known multilocus sequence types (MLST) in Lithuania. The minimum inhibitory concentration (MIC) values ciprofloxacin, tetracycline, gentamycin, ceftriaxone erythromycin were the agar dilution method. MIC compared MLST to find possible associations among isolation source, type antibiotics....
In recent years, the number of foodborne infections with non-O1 and non-O139
Campylobacter (C.) jejuni is the leading cause of human campylobacteriosis worldwide. We performed a molecular epidemiological study to investigate genetic relationship among C. strains isolated from diarrhoeal patients, broiler products and dairy cattle in Lithuania.The isolates clinical cases, were genotyped using multilocus sequence typing (MLST). Allele numbers for each housekeeping gene, type (ST), clonal complex (CC) assigned by submitting DNA sequences MLST database (...
Viable but non-culturable (VBNC) state is referred to as a dormant of non-sporulating bacteria enhancing the survival in adverse environments. To our knowledge, only few studies have been conducted on whole genomic expression Vibrio parahaemolyticus VBNC state. Since degradation nucleic acids V. vulnificus has detected, we hypothesize that gene regulation cells highly reduced, downregulation dominant and metabolic functions crucial for are kept sustained basis. Hence, performed...