A5076026829- Lichen and fungal ecology
- Botany and Plant Ecology Studies
- Bryophyte Studies and Records
- Lung Cancer Treatments and Mutations
- Natural Compounds in Disease Treatment
- Computational Drug Discovery Methods
- Cancer Genomics and Diagnostics
- Biochemical Analysis and Sensing Techniques
- Olfactory and Sensory Function Studies
- Natural Antidiabetic Agents Studies
- Biological Activity of Diterpenoids and Biflavonoids
- Natural product bioactivities and synthesis
- Cancer-related Molecular Pathways
- melanin and skin pigmentation
National Yang Ming Chiao Tung University
2025
Institute of Biomedical Sciences, Academia Sinica
2025
Vietnam National University Ho Chi Minh City
2020-2023
Ho Chi Minh City University of Science
2019
Western University of Health Sciences
2012
Abstract TP53 mutations are recognized to correlate with a worse prognosis in individuals non-small cell lung cancer (NSCLC). There exists an immediate necessity pinpoint selective treatment for patients carrying mutations. Potential drugs were identified by comparing drug sensitivity differences, represented the half-maximal inhibitory concentration (IC50), between mutant and wild-type NSCLC lines using database analysis. In addition, clinical data from collected evaluate both their status...
To overcome the problems in liverwort collecting such as small size and easily mixed with other species wild, we have successfully cultivated Marchantia polymorpha L. under vitro conditions previous study. The aim of this study is to evaluate biological activities biomass a confirmation sufficient protocol cultivation species. Cultured was dried at temperature 45-50 oC constant weight ground into fine powder. coarse powder extracted organic solvents increasing polarization including...
Marchantia polymorpha L. is used as a folk medicine in India, China and some European countries for the treatment of inflammation, cure cuts, wounds, diuretics, etc. Natural compounds biological activities this liverwort have been studied world few years. At present time, studies on bryophytes (non-vascular plants) are quite limited, especially Vietnam. Therefore, research focused investigating analyzing major secondary metabolites M. collected at Da Lat, Lam Dong. Among four extracted...
Purpose Resistance to cancer chemotherapy is a major problem. Herb-drug combinations can offer new potential overcome such resistance. To quantitatively assess chemosensitizing effects of herb-drug (HDC), approach that takes into account both the effect (CE) and “safety” considerations HDC proposed used in describing cytotoxic activity Tripterygium wilfordii-docetaxel (TW-Dtx) combination on prostate cell lines.
White mulberry (Morus alba L.) root was reported to contain potential tyrosinase inhibitors such as norartocarpetin, streppogenin, oxyresveratrol (5, 7, 2′, 4′-tetrahydroxy-flavavone) and 2-arylbenzofuran. This study aims at investigating Morus L. hairy culture create a source of for skin-whitening application. leaf (including mesophyll petiole) stem explants were randomly wounded inoculated with Agrobacterium rhizogenes ATCC 15834 in 10-40 minutes, coculturing 4 days. After inoculation,...
Introduction: The Bazzania genus, a type of liverwort known as low-level herbaceous organism, comprises approximately 250 species. Only 8 species have been chemically and biologically studied worldwide, none in Vietnam. This paper described the isolation structure elucidation six compounds isolated from sp. collected Lac Duong district, Lam Dong Province, Vietnam, July 2020. Methods: Phytochemical investigations n-hexane chloroform extracts led to pure compounds. Their chemical structures...