Zihua Li

ORCID: 0000-0002-6087-7459
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About
Contact & Profiles
Research Areas
  • Advanced Sensor and Energy Harvesting Materials
  • Conducting polymers and applications
  • Orthopedic Surgery and Rehabilitation
  • Foot and Ankle Surgery
  • Supercapacitor Materials and Fabrication
  • Tactile and Sensory Interactions
  • Extracellular vesicles in disease
  • Diet and metabolism studies
  • Osteoarthritis Treatment and Mechanisms
  • Legionella and Acanthamoeba research
  • MicroRNA in disease regulation
  • Cancer-related molecular mechanisms research
  • Inflammatory mediators and NSAID effects
  • Ferroptosis and cancer prognosis
  • Lymphoma Diagnosis and Treatment
  • Shoulder Injury and Treatment
  • Genomics and Phylogenetic Studies
  • Bone Tissue Engineering Materials
  • Bone fractures and treatments
  • Muscle metabolism and nutrition
  • Nanoplatforms for cancer theranostics
  • Bone Metabolism and Diseases
  • Advanced Materials and Mechanics
  • Cancer, Hypoxia, and Metabolism
  • RNA Research and Splicing

Shanghai Tenth People's Hospital
2022-2025

Tongji University
2020-2025

Tongji Hospital
2020-2025

Xian Yang Central Hospital
2023-2025

Xuzhou Medical College
2023-2025

The First People’s Hospital of Lianyungang
2023-2025

Hong Kong Polytechnic University
2021-2024

Shanghai Jiao Tong University
2023-2024

Renji Hospital
2022-2024

Harvard University
2023-2024

Osteoarthritis (OA) is characterized by cartilage degradation and subchondral bone remodeling. However, most available studies focus on either or lesion, alone, rarely pay attention to the synergy of these two pathological changes. Herein, a dual-functional medication developed simultaneously protect achieve repair. Black phosphorus nanosheets (BPNSs), with strong reactive oxygen species (ROS)-scavenging capability high biocompatibility, also present notable promoting effect in osteogenesis....

10.1021/acsnano.3c01789 article EN ACS Nano 2023-03-15

To develop intelligent wearable protection systems is of great significance to human health engineering. An ideal air filtration system should possess reliable efficiency, low pressure drop, healthcare monitoring function, and man-machine interactive capability. However, no existing covers all these essential aspects. Herein, we developed an (IWFS) via advanced nanotechnology machine learning. Based on the triboelectric mechanism, fabricated IWFS exhibits a long-lasting high particle...

10.1021/acsnano.3c02099 article EN ACS Nano 2023-03-30

Achieving flexible electronics with comfort and durability comparable to traditional textiles is one of the ultimate pursuits smart wearables. Ink printing desirable for e-textile development using a simple inexpensive process. However, fabricating high-performance atop good dispersity, stability, biocompatibility, wearability high-resolution, large-scale manufacturing, practical applications has remained challenging. Here, water-based multi-walled carbon nanotubes (MWCNTs)-decorated liquid...

10.1007/s40820-024-01362-z article EN cc-by Nano-Micro Letters 2024-03-11

Abstract Purpose To evaluate the trends and variations in global health burden of glaucoma by year, age sex, region socio‐economic status, using disability‐adjusted life years ( DALY s). Method The numbers, crude rate age‐standardized globally each country were obtained GBD 2015 study database. corresponding human development index HDI ) gross domestic product GDP per capita from United Nations World Bank. Environmental data WHO Global Health Observatory repository. Results From 1990 to...

10.1111/aos.14044 article EN Acta Ophthalmologica 2019-02-20

Abstract The emergence of fibrous energy harvesters and self‐powered sensors gives birth to functional wearable electronics. However, low power outputs, poor sensing abilities, limited material selections have greatly restricted their developments. Herein, novel polycation‐modified carbon dots (PCDs) tailored PCDs/polyvinyl alcohol nanocomposite polymer electrolytes (NPEs) are prepared used as dominating triboelectric materials construct a new NPEs‐based fiber nanogenerator (NPE‐TENG) for...

10.1002/adfm.202106731 article EN Advanced Functional Materials 2021-10-28

Flexible and stretchable triboelectric nanogenerators (TENGs) have been rapidly advanced owing to the demand for portable wearable electronic devices that can work under universal or motional circumstances. While versatile materials be applied in a TENG as dielectric materials, flexible cost-effective electrodes are crucially important output performance of TENGs. Herein, we developed poly(vinyl alcohol) (PVA) hydrogel doped with novel two-dimensional material, graphitic carbon nitride...

10.1021/acsami.3c17463 article EN ACS Applied Materials & Interfaces 2024-03-08

Developing a biphasic scaffold that can concurrently regenerate both cartilage and bone of osteochondral defects (OCDs) is challenge. Fish collagen (FC) currently considered an alternative to mammalian (MC) due its safety, accessibility, lower price, similar biological properties compared those MC. Here, we developed bilayer FC-based composite scaffolds with different components pore sizes modulate the differentiation fate marrow stem cells (BMSCs): chondroitin sulfate-incorporated FC...

10.1016/j.matdes.2020.108947 article EN cc-by-nc-nd Materials & Design 2020-07-15

Abstract Tribopositive, scalable, and biocompatible materials are highly desired for high‐performance triboelectric nanogenerators (TENGs). In this study, polyethylenimine (PEI) functionalized N‐doped carbon dots (NCDs‐PEI) synthesized a novel approach to develop high‐output TENGs by incorporating high permittivity NCDs‐PEI into polyvinyl alcohol (PVA) as the tribopositive composite (CPP composite) is proposed first time. By systematically manipulating mass ratio of NCDs/PVA...

10.1002/aenm.202101294 article EN Advanced Energy Materials 2021-06-21

Long non-coding RNAs (lncRNAs) have been reported to a crucial impact on the pathogenesis of acute myeloid leukemia (AML). Cuproptosis, copper-triggered modality mitochondrial cell death, might serve as promising therapeutic target for cancer treatment and clinical outcome prediction. Nevertheless, role cuproptosis-related lncRNAs in AML is not fully understood.The RNA sequencing data demographic characteristics patients were downloaded from The Cancer Genome Atlas database. Pearson...

10.1186/s12859-023-05148-9 article EN cc-by BMC Bioinformatics 2023-02-03

Abstract The immunosuppressive tumor microenvironment (ITME) of osteosarcoma (OS) poses a significant obstacle to the efficacy existing immunotherapies. Despite attempt novel immune strategies such as checkpoint inhibitors and vaccines, their effectiveness remains suboptimal due inherent difficulty in mitigating ITME simultaneously from both system. promotion anti‐tumor immunity through induction immunogenic cell death activation cGAS‐STING pathway has emerged potential counter stimulate...

10.1002/adhm.202400623 article EN Advanced Healthcare Materials 2024-05-01

In this study, we used bioinformatics tools, and experiments with patient tissues human mesenchymal stem cells (hMSCs) to identify differentially regulated genes (DEGs) microRNAs (miRNAs) that promote postmenopausal osteoporosis.By analyzing the GSE56815 dataset from NCBI GEO database, identified 638 DEGs, including 371 upregulated 267 downregulated genes, in women low bone density.Enrichment protein-protein interaction network analyses showed TP53, RPS27A, VEGFA were top three hub highest...

10.18632/aging.103223 article EN cc-by Aging 2020-05-19
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