A5076786029- Hypothalamic control of reproductive hormones
- Reproductive biology and impacts on aquatic species
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Neuropeptides and Animal Physiology
- Animal Behavior and Reproduction
- Zebrafish Biomedical Research Applications
- Neuroendocrine regulation and behavior
- Animal Behavior and Welfare Studies
- Circadian rhythm and melatonin
- Stress Responses and Cortisol
- Birth, Development, and Health
- Aquaculture Nutrition and Growth
- Regulation of Appetite and Obesity
- Congenital heart defects research
- Ovarian function and disorders
- Cardiovascular, Neuropeptides, and Oxidative Stress Research
- Sperm and Testicular Function
- Blood groups and transfusion
- Biochemical and Structural Characterization
- Animal Genetics and Reproduction
- Evolutionary Psychology and Human Behavior
- Fish Ecology and Management Studies
- Telomeres, Telomerase, and Senescence
- Plant Reproductive Biology
- Sexual function and dysfunction studies
Instituto Gulbenkian de Ciência
2021-2025
Consejo Superior de Investigaciones Científicas
2011-2016
Instituto de Acuicultura Torre de la Sal
2015-2016
Hospital Sierrallana
2016
This study, conducted in the brain of a perciform fish, European sea bass, aimed at raising antibodies against precursor kisspeptins order to map kiss systems and correlate expression kisspeptins, kiss1 kiss2, with that kisspeptin receptors (kiss-R1 kiss-R2). Specific could be raised preprokiss2, but not preoprokiss1. The data indicate kiss2 neurons are mainly located hypothalamus project widely subpallium pallium, preoptic region, thalamus, pretectal area, optic tectum, torus...
Some teleost species, including European sea bass, harbor two different kisspeptin coding genes: kiss1 and kiss2. Both genes are expressed in the brain, but their differential roles central control of fish reproduction only beginning to be elucidated. In this study, we have examined effects intracerebroventricular injections highly active bass peptides Kiss1-15 Kiss2-12 on spermiating male bass. Physiological saline, Kiss1-15, or was injected into third ventricle. To establish gene...
Kisspeptins are key players in the neuroendocrine control of puberty and other reproductive processes mammals. Several studies have demonstrated that KISS/GPR54 system is expressed by gonadotrophs, but vitro assessing direct stimulatory effects kisspeptin on gonadotropin secretion pituitary provided conflicting results. In this study, we investigated whether directly influences function sea bass pituitary. First, highly active peptides Kiss1-15 Kiss2-12 were used to stimulate dispersed cells...
Cognitive judgement bias in decision-making under ambiguity occurs both animals and humans, with some individuals interpreting ambiguous stimulus as positive (optimism) others negative (pessimism). We hypothesize that is a personality trait pessimistic would be more reactive to stressors therefore susceptible stress-related diseases than optimistic ones. Here, we show zebrafish judgment consistent behavioral over time, fish express phenotype-specific neurogenomic responses stress....
The role of telomerase reverse transcriptase has been widely investigated in the contexts ageing and age-related diseases. Interestingly, decreased activities (and accelerated telomere shortening) have also reported patients with emotion-related disorders, opening possibility for subjective appraisal stressful stimuli playing a key stress-driven shortening. In fact, showing pessimistic judgement bias shorter telomeres. However, humans evidence this is correlational causal directionality...
Two forms of kiss gene (kiss1 and kiss2) have been described in the teleost sea bass. This study assesses cloning characterization two Kiss receptor genes, namely kissr2 kissr3 (known as gpr54-1b gpr54-2b, respectively), their signal transduction pathways response to Kiss1 Kiss2 peptides. Phylogenetic synteny analyses indicate that these paralogs originated by duplication an ancestral before specific duplication. The mRNAs encode proteins 368 378 amino acids, respectively, share 53.1%...
Optimistic and pessimistic cognitive biases have been described in many animals are related to the perceived valence of environment. We, therefore, hypothesize that such bias can be adaptive depending on environmental conditions. In reward-rich environments, an optimistic would favoured, whereas harsh a one thrive. Here, we empirically investigated potential value using zebrafish as model. We first phenotyped female optimistic/pessimistic axis previously validated judgement assay. females...
In this protocol, we describe for the first time a judgment bias paradigm to phenotype way zebrafish assess ambiguous stimuli. We have developed and validated protocol test based on Go/No-go task, performed using half radial maze. After habituation phase, fish are trained discriminate between two reference arms [positive (P) negative (N)]. For purpose, they experience positive event (food reward in P), when presented with specific location/color cue, (chasing net N), different cue....
Abstract Cognitive judgement bias in decision-making under ambiguity occurs both animals and humans, with some individuals interpreting ambiguous stimulus as positive (optimism) others negative (pessimism). We hypothesize that is a personality trait pessimistic would be more reactive to stressors therefore susceptible stress-related diseases than optimistic ones. Here, we show zebrafish judgment consistent behavioral over time, fish express phenotype-specific neurogenomic responses stress....
Some animal species exhibit considerable physiological and behavioural alterations in response to captivity. It has been hypothesized, but rarely tested, that such changes reflect a negative affective state is associated this specific context. In the last years, judgement bias measures have emerged as reliable indicators of state, under assumption individuals are more likely evaluate ambiguous stimuli display therefore pessimistic behaviours. Here, we developed task for juvenile European sea...
ABSTRACT Reproduction is a highly demanding biological process that occurs at the optimal time of year and day to ensure success spawn offspring. Melatonin hormone that, secreted mainly by pineal gland, plays critical role in integration photoneuroendocrine information from environment (annual daily variations) modulate reproductive activity gonadal development fish. In this study we assessed effect exogenous melatonin on circadian levels sex steroids gonadotropins pubertal 2 yr-old male sea...
Poster presentado en el 9th International Symposium on Reproductive Physiology of Fish celebrado Cochin (India) del 9 al 14 de agosto 2011