Costel Vasile Siserman

ORCID: 0000-0002-6124-8582
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About
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Research Areas
  • COVID-19 Clinical Research Studies
  • Suicide and Self-Harm Studies
  • Reproductive tract infections research
  • Medical Malpractice and Liability Issues
  • COVID-19 and Mental Health
  • SARS-CoV-2 and COVID-19 Research
  • Long-Term Effects of COVID-19
  • Homicide, Infanticide, and Child Abuse
  • Stress Responses and Cortisol
  • Tryptophan and brain disorders
  • Health and Well-being Studies
  • Intimate Partner and Family Violence
  • Psychology of Development and Education
  • COVID-19 diagnosis using AI
  • Cardiovascular Effects of Exercise
  • Sinusitis and nasal conditions
  • Psychopathy, Forensic Psychiatry, Sexual Offending
  • Cervical Cancer and HPV Research
  • Resilience and Mental Health
  • Traumatic Brain Injury and Neurovascular Disturbances
  • Sexuality, Behavior, and Technology
  • Syphilis Diagnosis and Treatment
  • Adolescent Sexual and Reproductive Health
  • Deception detection and forensic psychology
  • Dermatological and COVID-19 studies

Iuliu Hațieganu University of Medicine and Pharmacy
2018-2024

Sudden cardiac death (SCD) remains a critical public health problem, prompting efforts to understand its underlying causes and identify patients at risk. Despite declining cardiovascular mortality in developed nations, SCD still claims millions of lives annually, disproportionately affecting men older individuals with higher prevalence ischemic heart disease. This study aimed investigate the potential association between macroscopic microscopic diagnoses cases based on cohort 3438...

10.47162/rjme.65.4.20 article EN Romanian Journal of Morphology and Embryology 2025-02-13

The present work addresses the controversial issue of incest by men.We sought to highlight that incestuous tendency in men becomes a sexual preference isn't determined directly existence borderline or other personality traits early maladaptive cognitive schemas.A sample 48 males with confirmed tendencies was selected.49% them showed and abandonment schemas, their median age being m=38.17 SD ±9.24 mean educational level, m= 13.11 ±1.71.Data collected Millon Multiaxial Clinical Inventory-III,...

10.51847/tgvmue7esx article EN cc-by-nc-sa Archives of Pharmacy Practice 2023-01-01

COVID-19-associated rhino-orbital mucormycosis has become a new clinical entity. This study’s aim was to evaluate the histopathological and ultramicroscopic morphological aspects of this fungal infection. an observational retrospective study on eight patients from three tertiary centers in Romania. The tissue samples collected during functional endoscopic sinus surgery were studied through examination, scanning electron microscopy, transmission microscopy. In characteristic all cases...

10.3390/diagnostics14040429 article EN cc-by Diagnostics 2024-02-15

Objective. The present research addresses the respondents’ emotional state regarding fear of Sars- CoV-2 contamination and rational-emotional attitude. Specifically, we are interested in whether catastrophic perceptual- evaluations can intensify maladaptive emotions behaviors case forensic staff.<br />Methods. study included 91 participants from Romanian Forensic Medicine Network, randomized, using DA-COVID Scale19, Delcea C Siserman C, 2020, electronic / online version order to assess...

10.4323/rjlm.2021.142 article EN Romanian Journal of Legal Medicine 2021-01-10

The presence of SARS-CoV-2 in the middle ear reveals etiopathogenesis otitis media COVID-19, as well an epidemiological risk during otologic examination and surgical procedures COVID-19 patients. study included 8 deceased patients with COVID-19. Tissue samples from were subjected to virology, histopathology, scanning (SEM) transmission (TEM) electron microscopy investigation. Ethmoidal mucosa processed for virology analyses. qPCR resulted positive 75% nasal 50% samples. Ct values showed...

10.3390/diagnostics11091535 article EN cc-by Diagnostics 2021-08-25

Stress is perceived as a common, almost inevitable problem that most people face on daily basis all levels. In this field, special sector, due to the multiple implications, occupational stress. Despite theoretical or practical applicative development approached by specialists from various fields over time, issue of stress still offers, perhaps today more than ever, possibility and need new analytical investigative openings leading effective control it. Mental health puts its mark medical act...

10.4323/rjlm.2020.442 article EN Romanian Journal of Legal Medicine 2020-12-10

(1) Background: Sexually transmitted infections (STIs) are among the most common worldwide, many of these being caused by Neisseria gonorrhoeae (NG). Increased antimicrobial NG resistance has been reported in recent decades, highlighting need for new sources natural compounds with valuable activity. This study aims to determine effect propolis extracts on strains, including antibiotic-resistant strains. (2) Methods: First void urine samples from presumed positive STI subjects were harvested....

10.3390/antibiotics10060689 article EN cc-by Antibiotics 2021-06-08

Aim, methods and outcomes. In this research, the mediators of domestic violence were approached from psychological, psychiatric, forensic theoretical-experimental paradigm perspective, but also by studying working hypotheses issue regarding correlations between (personality disorders) participants’ behavioral output experimental perspective. The research included 3 samples: 2 control samples one sample. These are part Institute Forensic Medicine Cluj-Napoca database. gross results examined...

10.4323/rjlm.2020.166 article EN Romanian Journal of Legal Medicine 2020-06-15

Infection with hepatitis B virus (HBV) is a major problem worldwide. The histocompatibility complex plays an essential role in host immunity and can help eliminate the HBV of infected hepatocytes. Our study aimed to determine certain human leukocyte antigen (HLA) class II molecules (i.e. HLA-DRB1 HLA-DQB1) persistence or removal HBV. Sixty patients confirmed be HBV-positive via real-time polymerase chain reaction (PCR), i.e. people chronic active hepatitis, were included along control group...

10.1080/08820139.2018.1489832 article EN Immunological Investigations 2018-07-06

(1) Background: Chronic rhinosinusitis with nasal polyps (CRSwNP) is one of the most studied rhinological disorders. Modifications respiratory mucosa in COVID-19 patients are so far unknown. This paper presents a comparative morphological characterization CRSwNP versus and tissue interleukin (IL)-33 concentration. (2) Methods: We analyzed samples through histopathology, scanning transmission electron microscopy performed proteomic determination IL-33. (3) Results: Histopathologically,...

10.3390/jcm10184110 article EN Journal of Clinical Medicine 2021-09-12

At present, the autopsy reports are based on a subjective, descriptive method. The technical progress of imagistic domain led to development objective, non-invasive and non-destructive methods, whose utility manifested itself within forensic medicine, too. It developed concept virtopsy, an alternative conventional autopsy, using modern techniques, results were quantified in comparison this. Results show that case this uniform objective method preserves evidence, some data important for...

10.4323/rjlm.2010.75 article EN Romanian Journal of Legal Medicine 2010-01-01

The Delta variant (Pango lineage B.1.617.2) is one of the most significant and aggressive variants SARS-CoV-2. To best our knowledge, this first paper specifically studying pulmonary morphopathology in COVID-19 caused by B.1.617.2 variant. study included 10 deceased patients (40-83 years) with necrotic lung fragments were obtained either biopsy (six cases) or autopsy (four cases). Tissue samples subjected to virology analysis for identification SARS-CoV-2 variant, histopathology,...

10.3390/jpm13020279 article EN Journal of Personalized Medicine 2023-01-31

In this study, we aimed to investigate whether specific HLA alleles found in patients from Romania and the Republic of Moldova were associated with severity COVID-19 infection its mortality. We analyzed at -A, -B, -C, -DRB1, -DQB1 loci a cohort 130 individuals severe extremely forms COVID-19, including 44 who died. compared these findings control group consisting had either not been diagnosed or experienced mild disease. Using multivariate logistic regression models, discovered that B*27...

10.3390/ijms25021326 article EN International Journal of Molecular Sciences 2024-01-22

This work represents an overview of the theoretical-experimental basis reasoning, reasoning mediated by cognitive instruments used in decision making process, case individuals imprisoned for murder on one hand, and who have not committed other hand. Beginning from theoretical approach, we will research 492 (N=492) respondents to study, which 246 female male, divided into a non-imprisoned group. The purpose this is contribute better clinical conceptualisation target patient suspected murder,...

10.4172/2471-4372.1000160 article EN Deleted Journal 2018-01-01

Suicide rates reflect the mental health status in certain countries or regions. As COVID-19 infection developed as a pandemic and governments imposed measures to stop spread of virus, was affected worldwide. Romania no exception government issued complete lockdown with restriction regarding travels, social gatherings, transition working from home others. The increase rate unemployment, difficulties accessing services distancing generated by restrictions had major impact on lifestyle...

10.1080/13811118.2021.2022052 article EN Archives of Suicide Research 2022-01-18

Transylvania is a historical region in the northwestern part of Romanian with rather heterogeneous population. Our study first to determine human leukocyte antigen (HLA) profiles large population sample from this and compare them other European groups. HLA genes were examined 2,794 individuals using Single Specific Primer-Polymerase Chain Reaction (SSP-PCR) Polymerase Sequence-Specific Oligonucleotide (PCR-SSO) methods. All samples tested for HLA-A locus, 2,773 HLA-B, 1,847 HLA-C, 2,719...

10.1155/2019/1342762 article EN cc-by Journal of Immunology Research 2019-12-30

In the present study, we aimed to assess and analyze predictive factors of 30‑day mortality in patients with acute subdural hematoma (ASDH) who underwent surgical intervention after traumatic brain injury (TBI). We conducted a retrospective which included cohort 135 consecutive diagnosed ASDH required evacuation. assessed demographic clinical data, imaging data described by preoperative computed tomography (CT) type neurosurgical for evacuation via either craniectomy or craniotomy. The were...

10.3892/etm.2021.10189 article EN Experimental and Therapeutic Medicine 2021-05-13

(1) Background: Affective distress can be triggered by aggressive stimuli with an unfavorable role for the individual. Some of factors that lead to development and evolution a mental disorder genetic. The aim this study is determine some correlations between human leukocyte antigen (HLA) genes affective profile (PDA). (2) Methods: A psychological assessment testing tool anxiety was applied 115 people. low-resolution HLA alleles class I (HLA-A, HLA-B, HLA-C) II (HLA-DRB1 HLA-DQB1) were...

10.3390/ijerph191912608 article EN International Journal of Environmental Research and Public Health 2022-10-02

We aimed to evaluate the primary lung postmortem macro- and microscopic biomarkers factors associated with diffuse alveolar damage in patients fatal coronavirus (COVID-19). retrospectively analyzed tissue collected from autopsies performed Cluj-Napoca, Romania, between April 2020 2021 on severe acute respiratory syndrome 2 (SARS-CoV-2). examined 79 confirmed SARS-CoV-2 infection, ages 34 96 years, split into two groups using cut-off value of 70 years. Arterial hypertension (38%) type...

10.3390/diagnostics13122039 article EN cc-by Diagnostics 2023-06-12
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