A5038259032- Autopsy Techniques and Outcomes
- Fetal and Pediatric Neurological Disorders
- Urological Disorders and Treatments
- Prenatal Screening and Diagnostics
- Iron Metabolism and Disorders
- Cerebrospinal fluid and hydrocephalus
- Assisted Reproductive Technology and Twin Pregnancy
- Radiomics and Machine Learning in Medical Imaging
- Ectopic Pregnancy Diagnosis and Management
- IL-33, ST2, and ILC Pathways
- Ear and Head Tumors
- Injury Epidemiology and Prevention
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- COVID-19 and healthcare impacts
- Parvovirus B19 Infection Studies
- Sinusitis and nasal conditions
- Cleft Lip and Palate Research
- Ear Surgery and Otitis Media
- Vestibular and auditory disorders
- Craniofacial Disorders and Treatments
- Pregnancy and preeclampsia studies
- Medical Coding and Health Information
- COVID-19 Impact on Reproduction
- Advanced Neuroimaging Techniques and Applications
- Nanoparticle-Based Drug Delivery
Iuliu Hațieganu University of Medicine and Pharmacy
2018-2024
Clinical Emergency Hospital Bucharest
2010-2021
John Wiley & Sons (United Kingdom)
2019
Hudson Institute
2019
Centre of Advanced Studies
2018
University of Medicine and Pharmacy of Craiova
2016
Carol Davila University of Medicine and Pharmacy
2010
Abstract Objective The aim of this study was to establish the diagnostic accuracy high‐field magnetic resonance imaging (MRI) at 7 Tesla (T) compared with that stereomicroscopic autopsy for assessing first trimester fetuses. Methods Nine consecutive cases fetuses resulting from spontaneous and therapeutic pregnancy termination were considered. divided into two groups according gestational age: Embryo Group nine 10 weeks (GWs) Fetus 13 GWs. group scanned using three‐dimensional fast steady...
Magnetic resonance imaging (MRI) contrast agents are pharmaceuticals that enable a better visualization of internal body structures. In this study, we present the synthesis, MRI signal enhancement capabilities, in vitro as well vivo cytotoxicity results gold-coated iron oxide nanoparticles (Fe
The presence of SARS-CoV-2 in the middle ear reveals etiopathogenesis otitis media COVID-19, as well an epidemiological risk during otologic examination and surgical procedures COVID-19 patients. study included 8 deceased patients with COVID-19. Tissue samples from were subjected to virology, histopathology, scanning (SEM) transmission (TEM) electron microscopy investigation. Ethmoidal mucosa processed for virology analyses. qPCR resulted positive 75% nasal 50% samples. Ct values showed...
(1) Background: Chronic rhinosinusitis with nasal polyps (CRSwNP) is one of the most studied rhinological disorders. Modifications respiratory mucosa in COVID-19 patients are so far unknown. This paper presents a comparative morphological characterization CRSwNP versus and tissue interleukin (IL)-33 concentration. (2) Methods: We analyzed samples through histopathology, scanning transmission electron microscopy performed proteomic determination IL-33. (3) Results: Histopathologically,...
The examination of very small fetal hearts requires special equipment and a specialist that are not available in many general pathology laboratories. Compared to conventional examination, the four-chamber cardiac dissection (4CCD) method can be performed by any pathologist using instruments generally services. aim this study is evaluate efficiency 4CCD post-mortem magnetic resonance imaging (pm-MRI) at 7T as standard. Twelve fetuses with gestational ages between 13 19 weeks have been...
Ventriculomegaly (VM) is a fetal brain malformation which may present independently (isolated form) or in association with different cerebral malformations, genetic syndromes other pathologies (non-isolated form).This paper aims to study the effect of ventriculomegaly on internal tridimensional architecture brains by way Klingler's dissection. was diagnosed using ultrasonography during pregnancy and subsequently confirmed necropsy. Taking into consideration diameter lateral ventricle...
Objective To determine the diagnostic value of virtual autopsy using post mortem-MRI (pm-MRI) at 3Tesla (T) compared to classic for confirmation fetal structural anomalies and secondly establish which cases termination pregnancy would benefit mostly from a autopsy. Methods In each 32 fetuses included in study, anatomical structures were assessed, after second trimester. All evaluated by prenatal ultrasonography, autopsy, then divided into four groups: Cerebral Group, Cardiac Renal Group...
Diastematomyelia consists in dividing into two hemi spinal cord cords symmetric and asymmetric the presence of a bone spur. Malformation is more common women, this paper presents case patient with rare dysmorphism, terms imaging, MRI only method exploration that can establish diagnosis also highlight malformations associated.
ABSTRACT Objective To determine the diagnostic accuracy of virtual autopsy using whole‐body postmortem ultra‐high field magnetic resonance imaging (MRI) at 7 Tesla (T), a short T2‐weighted (T2‐WI) protocol, compared with classical autopsy, for detecting structural abnormalities in small second‐trimester fetuses. Methods Thirty consecutive fetuses 13–19 weeks' gestation (weight, 17–364 g) were included following spontaneous pregnancy loss or termination pregnancy. After fixation 10%...
Introduction: This research aims to describe a progressive pattern of ultrasound placental remodeling in patients with history SARS-CoV-2 infection during pregnancy. Materials and Methods: was longitudinal, cohort study which enrolled 23 pregnant women former mild the current Four obstetricians analyzed images from different gestational ages following COVID identified presence degree remodeling. We assessed inter-rater agreement interclass correlation coefficients. Pathology workup included...
Twin reversed arterial perfusion (TRAP) sequence is a rare and severe complication specific to monochorionic twin pregnancies, involving the presence of an acardiac structurally normal co-twin (pump twin). We report on case a33-year-old female with biamniotic pregnancy complicated TRAP polyhydramnios. The patient underwent fetoscopic termination at 34 gestational weeks (GW) was readmitted aretroplacental hematoma. gave birth through caesarean section living fetus, weighing 1480 g. To best...
To determine whether the cheilognathopalatoschisis is syndromic or non-syndromic. Cheilognathopalatoschisis complex cleft (involves of lip, upper jaw, and hard soft palates) a severe birth defect. It occurs isolated associated with other medical conditions. A 29-year-old Caucasian female, pregnant for first time, was referred at 17 weeks' gestation routine prenatal ultrasound. The couple had normal general health not consanguineous. There no family history cheilognathopalatoschisis. Routine...
Background: Performing accurate autopsies on small foetuses is a difficult process to achieve, especially when certain degree of autolysis involved. High-field MRI 7 T has proven be useful tool describe anatomy, therefore the purpose our study was establish its diagnostic usefulness assessing first trimester compared stereomicroscopic autopsy or microscopic evaluation.
In the following section we aim to present an unusual case of polimalformed fetus with Trisomy 18 diagnosed at seven gestational weeks and 3 days. A 35-year-old G1P0 without any known pathologies came for a routine scan 7 weeks. At first scan, intrauterine pregnancy abnormal caudal appearance could be seen (figure1). The next appointment was scheduled in two weeks, but five days later patient reexamined due vaginal bleeding. diagnosis nonviable trimester formulated (embryo same ultrasound...
Objective. The aim of our study was to establish if high-field post-mortem MRI at 7T can perform three-dimensional measurements the fetal heart, and retrieve results comparable macroscopic performed autopsy, in fetuses with whole body weight below 500 g. Methodology. Twelve second-trimester gestational ages ranging from 13 19 weeks gestation were considered. All resulted therapeutic termination pregnancy (TOP) due plurimalformative syndromes or chromosomal anomalies. cases immersed 10%...