A5070186462- Biomedical Text Mining and Ontologies
- Machine Learning in Healthcare
- COVID-19 Clinical Research Studies
- Clinical Laboratory Practices and Quality Control
- Long-Term Effects of COVID-19
- Platelet Disorders and Treatments
- Venous Thromboembolism Diagnosis and Management
- Colorectal Cancer Treatments and Studies
- Electronic Health Records Systems
- Reliability and Agreement in Measurement
- Artificial Intelligence in Healthcare and Education
- Inflammatory Biomarkers in Disease Prognosis
- Renal Transplantation Outcomes and Treatments
- Bariatric Surgery and Outcomes
- Neurological Complications and Syndromes
- Blood properties and coagulation
- Aortic Disease and Treatment Approaches
- Complement system in diseases
- Renal function and acid-base balance
- Liver Disease Diagnosis and Treatment
- Blood groups and transfusion
- Aortic aneurysm repair treatments
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- Hemophilia Treatment and Research
- Meta-analysis and systematic reviews
Odense University Hospital
2016-2025
University of Southern Denmark
2023-2025
Lillebaelt Hospital
2019-2023
Maersk (Denmark)
2023
Vejle Sygehus
2018
Major bleeding is a severe complication in critically ill medical patients, resulting significant morbidity, mortality, and healthcare costs. This study aims to assess the incidence risk factors for major hospitalised patients using Natural Language Processing (NLP) model. We conducted retrospective, cross-sectional observational electronic health records of adult admitted through Emergency Department at Odense University Hospital from January 2017 December 2022. during admission was...
In this nested case-control study, we evaluated haematological and morphological parameters of hospitalised patients with real-time polymerase chain reaction verified COVID-19 infection compared to similar symptomatology but without infection. Seventy-four positive 228 negative were routine parameters. Severe disease was defined as death and/or need intensive care treatment. Twenty-seven 18 furthermore included for evaluation using smear examination. Significant differences found platelet...
Studies on markers for bleeding risk among thrombocytopenic cancer patients are lacking. This prospective observational cohort study investigated whether platelet parameters and a standardised questionnaire predicted or prophylactic transfusions in with thrombocytopenia. Admitted adult count <80 × 109/L were enrolled, but excluded if they experienced surgery trauma within 7 days transfusion 14 days. Patients interviewed, blood samples collected and, subsequently, spontaneous 30 registered.Of...
Abstract Background The epidermal growth factor receptor (EGFR) system is involved in cancer pathogenesis and serves as an important target for multiple treatments. EGFR its ligands (EGF), heparin-binding (HB-EGF), betacellulin (BTC), amphiregulin (AREG) transforming α (TGF-α) have potential applications prognostic or predictive serological biomarkers cancer. aim was to establish ligand reference intervals healthy women. Methods were measured serum from 419 women aged 26–78 years. need age...
The complement system, consisting of more than thirty different soluble and cell-bound proteins, exerts essential functions both in the innate adaptive immune systems is believed to be an important contributor allograft injury kidney transplantation. anaphylatoxins C3a C5a are powerful chemoattractants, recruiting effector cells toward site activation enhance T-cell response, while C3dg binding CR2 on B-cells, enhances B-cell immunity at several stages differentiation. Complement split...
Clinical machine learning algorithms have shown promising results and could potentially be implemented in clinical practice to provide diagnosis support improve patient treatment. Barriers for realisation of the algorithms’ full potential include bias which is systematic unfair discrimination against certain individuals favor others.The objective this work measure anatomical text algorithms. We define as algorithmic outcomes patients with medical conditions specific locations. degree across...
: In thrombocytopenia, differences in haemostatic capacity may explain discrepancies bleeding risk between patients with cancer and liver cirrhosis. The objective was to compare the different thrombocytopenic patient populations. We evaluated platelet aggregation using impedance aggregometry (Multiplate Analyzer), von Willebrand factor antigen (VWF:Ag), VWF:ristocetin-cofactor activity (VWF:RCo), activated partial thromboplastin time (aPTT), coagulation VIII, fibrinogen, thrombin generation...
Platelets play an important role in arterial diseases that extends beyond their traditional function hemostasis and thrombosis.[1] The development progression of ascending thoracic aortic dilations (ATADs) abdominal (AADs) have been associated with increased platelet activation response.[1] [2] Consequently, platelets suggested as potential medical targets to slow expansion rates reduce risk ruptures.