Raphaelle Sousa Borges

ORCID: 0000-0002-6145-7130
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About
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Research Areas
  • Zebrafish Biomedical Research Applications
  • Aquaculture disease management and microbiota
  • Essential Oils and Antimicrobial Activity
  • Aquaculture Nutrition and Growth
  • Digital Mental Health Interventions
  • Phytochemistry and Biological Activities
  • Phytochemicals and Medicinal Plants
  • Ethnobotanical and Medicinal Plants Studies
  • Milk Quality and Mastitis in Dairy Cows
  • Child and Adolescent Health
  • Animal testing and alternatives
  • Probiotics and Fermented Foods
  • Digestive system and related health
  • Neuroscience and Neuropharmacology Research
  • Phytochemistry and biological activity of medicinal plants
  • Pomegranate: compositions and health benefits
  • Bee Products Chemical Analysis
  • Phytochemistry and Bioactivity Studies
  • Neuroinflammation and Neurodegeneration Mechanisms

Universidade Federal do Amapá
2016-2021

Universidade Estadual do Amapá
2021

Endopleura uchi, is used for the treatment of inflammatory disease and related to female reproductive tract. The aim this study was evaluate acute toxicity uchi stem bark hydroethanolic extract (EEu) in zebrafish, emphasizing histopathological biochemical parameters, as well evaluating silico pharmacokinetic toxicological parameters phytochemical/pharmacological marker, bergenin, their metabolites. animals were orally treated with EEu at a single dose 75 mg/kg, 500 1000 mg/kg 3000 mg/kg....

10.1016/j.toxrep.2020.01.011 article EN cc-by-nc-nd Toxicology Reports 2020-01-01

Abstract Fatty amides ( N -alkylamides) are a group of bioactive lipids widely distributed in microorganisms, animals, and plants. The low yield the extraction process spilantol, grease amide, which has been related mainly to diverse biological effects, compromises its application on large scale. Thus, this study proposed an alternative synthesis fatty from Bertholletia excelsa (AGBe) oil, with chemical structure similar that spilantol. In vivo models induced by carrageenan were used...

10.21203/rs.3.rs-437833/v1 preprint EN cc-by Research Square (Research Square) 2021-06-04
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