A5041289907- Essential Oils and Antimicrobial Activity
- Phytochemistry Medicinal Plant Applications
- Phytochemicals and Antioxidant Activities
- Agricultural and Food Sciences
- Microencapsulation and Drying Processes
- Natural product bioactivities and synthesis
- Animal Nutrition and Physiology
- Psidium guajava Extracts and Applications
- Bee Products Chemical Analysis
- Insect Pest Control Strategies
- Sesquiterpenes and Asteraceae Studies
- Antioxidant Activity and Oxidative Stress
- Plant biochemistry and biosynthesis
- Growth and nutrition in plants
- Botanical Research and Applications
- Analytical Chemistry and Chromatography
- Phytochemistry and Biological Activities
- Plant Toxicity and Pharmacological Properties
- Moringa oleifera research and applications
- Natural Antidiabetic Agents Studies
- Banana Cultivation and Research
- Pomegranate: compositions and health benefits
- melanin and skin pigmentation
- Analytical Methods in Pharmaceuticals
- Plant-Derived Bioactive Compounds
Universidade Federal de Goiás
2016-2025
Institute of Animal Science and Pastures
2021
Faculdades Guarulhos
2020
Universidade de São Paulo
2001-2018
National Institute of Amazonian Research
2018
Laboratoire de Vectorologie et Thérapeutiques Anticancéreuses
2018
Universidade Federal do Amapá
2017
Universidade Federal de Jataí
2016
Fundação de Apoio a Pesquisa do Estado de Goiás
2016
Blücher (Germany)
2014
Pterodon emarginatus Vogel is a Brazilian species that belongs to the family Fabaceae, popularly known as sucupira. Its oil has several biological activities, including potent larvicidal property against Aedes aegypti. This insect vector of dengue, tropical disease been considered critical health problem in developing countries, such Brazil. Most dengue control methods involve agents suspended or diluted water and making active lipophilic natural products available therefore technological...
A green solvent-based optimization for rosmarinic acid (RA), carnosol (COH), and carnosic (CA) extraction, the three main antioxidants from rosemary, was performed. The conventional solid-liquid extraction optimized using a central composite design (CCD) followed by desirability approach. In CCD analysis quantitative effects of time (4.8–55.2 min), liquid-to-solid ratio (4.6–21.4 mL g−1), ethanol content (44.8–95.2% v/v) were determined extracted amount antioxidants, their concentrations in...
Abstract The present investigation reports the microencapsulation of essential oil from fruits Pterodon emarginatus by spray drying using gum arabic and maltodextrin. X-ray diffraction studies established that was entrapped within microcapsules rather than being adsorbed onto surface. morphology analyzed scanning electron microscopy (SEM). particle size (Sauter [3,2]) distribution were also determined. evaluated for content stability both volatiles major component, β-caryophyllene, 45 days....
Myrcia tomentosa (Aubl.) DC., Myrtaceae, found in Central Brazilian Cerrado and popularly known as "goiaba-brava", belongs to the genus, which has several species with medicinal properties such as: hypoglycemic, diuretic, hypotensive, antidiarrheal, antimicrobial antitumor. The present study aimed analyzed environmental infl uence on concentrations of phenolic metabolites M. leaves. Compounds assayed leaves were: total phenols, tannins by protein precipitation, hydrolysable fl avonoids...
In this work, spray-dried rosemary extracts were obtained. A 33 Box–Behnken design was followed to evaluate the influence of drying conditions on contents chemical markers and "in vitro" antioxidant activity powder. Although dry products lost some their polyphenols, they still had activities (IC50) ranging from 17.6 24.8 μg · mL−1. Analysis variance proved that studied factors interactions significantly affected most quality indicators. The best combination use for obtaining with adequate...
Preparation of nanoformulations using natural products as bioactive substances is considered very promising for innovative larvicidal agents. On this context, oil in water nanoemulsions develop a main role, since they satisfactorily disperse poor-water soluble substances, such herbal oils, aqueous media. Pterodon emarginatus, popularly known sucupira, has oleoresin. However, to our knowledge, no previous studies were carried out evaluate its potential against Culex quinquefasciatus, the...
A 23 full factorial design was used to assess the impact of spraying air flow rate (30-50 L/min), drying inlet temperature (90-150 °C) and extract feed (4-6 g/min) on quality Eugenia dysenterica DC., Myrtaceae, spray-dried extracts. Response surface methodology (RSM) applied analyze signii cance effects process factors product obtain fitted equations predict dry powder properties. Powder yields were satisfactory, ranging from 34.64 63.92%. The dried products showed moisture contents water...
Cutaneous leishmaniasis (CL) is a neglected tropical skin disease caused by the protozoan genus Leishmania. The treatment restricted to handful number of drugs that exhibit toxic effects, limited efficacy, and drug resistance. Additionally, developing an effective topical still enormous unmet medical challenge. Natural oils, e.g. oleoresin from P. emarginatus fruits (SO), contain various bioactive molecules, especially terpenoid compounds such as diterpenes sesquiterpenes. However, its use...
Abstract The influence of concentration and incorporation time different drying excipients on the processing yields physical properties Eugenia dysenterica DC spray-dried extracts were investigated following a factorial design. Under established conditions, process yield ranged from 57.55 to 89.14%, in most experiments, recovered products presented suitable flowability compressibility, as demonstrated by Hausner factor, Carr index, angle repose. Additionally, general way, parameters related...
A 33 Box–Behnken design and Response Surface Methodology were performed to evaluate the influence of extract feed rate, drying air inlet temperature spray nozzle airflow rate on process yield, stability parameters (moisture content water activity) several physicomechanical properties spray-dried rosemary extracts. Powder yield ranged from 17.1 74.96%. The extracts showed moisture activity below 5% 0.5%, respectively, which indicate their chemical microbiological stabilities. Even without...
The Hancornia speciosa latex reveals angiogenic, osteogenic, and anti-inflammatory properties, which present its potential for developing of wound healing drugs; however, the compounds responsible angiogenesis remain unknown. One strategy to screen these active is evaluation fractions. This study aimed obtain different fractions evaluate angiogenic activity separately using chick chorioallantoic membrane (CAM) assay. serum (SE) fraction was angiogenesis, subject biochemical characterization...
Este estudo tem como objetivo revisar o conhecimento atual sobre tomate, os carotenoides, especialmente licopeno, destacando seus benefícios à saúde e as possibilidades de aproveitamento sustentável dos subprodutos da indústria processamento do tomate. Pertencente família das Solanáceas, tomate (Solanum lycopersicum L.) é uma hortaliças mais consumidas no mundo, apreciado tanto na forma in natura quanto em produtos industrializados. A tomateira gera grande volume resíduos, cujo manejo...
ABSTRACT: Phytoalexins are compounds that have been studied a few years ago, which present mainly antimicrobial activity. The plants of the family Poaceae most geographically widespread and stand out for their economic importance, once they cereals used as staple food. This stands having variety phytoalexins, can be synthesized via shikimic acid (the phenylpropanoids), or mevalonic acid, being considered terpenoid phytoalexins. characterization these with activity is carried using...
A simple HPLC‐UV method has been developed and validated for the quantification of ellagic acid (EA) in ethanol extracts Eugenia uniflora L. (Myrtaceae) leaves. The ultrasound‐assisted extraction (UAE) optimization was performed using a Box Behnken design (3 3 ) combined with response surface methodology to study effects concentration (%, w/w), time (minutes), temperature (°C) on EA concentration. optimized results showed that highest yield by UAE 26.0 μ g mL −1 when 44% (w/w) as solvent, 22...
Pterodon emarginatus Vogel, Fabaceae, is a great source of bioactive compounds. The most known and studied herbal derivative from this species an ambar-colored oleoresin that contains vouacapane diterpenes volatile terpenoids, such as β-caryophyllene. Some recent papers aimed to generate nanoemulsions using for biological applications. However, they used high-energy methods elevate costs the process or heating procedures, which offer disadvantage possible substances loss. Thus, part our...
Prior to obtain a standardized dried extract from V. ferruginea, lupeol was first time isolated leaves and used as chemical maker. An analytical method using HPLC-PDA for determination in ferruginea intermediate products developed C8 reverse-phase column, acetonitrile-acetic acid (99.99:0.01, v/v) mobile phase at 0.8 mL min-1, oven temperature 23-25 ºC, sample injection volume 30 µL detection 210 nm. The presented linearity 10 160 µg mL-1, accuracy, precision, robustness suitable sensitivity...
The fruits of guava, Psidium guajava L., Myrtaceae, are cultivated as food and used in agroindustries, generating byproducts or waste that represent environmental problems require adequate destination. However, these present high levels secondary metabolites have been awakened interest regarding to its reusing. extract was standardized ellagic acid concentration by performance liquid chromatography. additivation capacity the vitro photoprotective efficacy guava byproduct verified a result...
This study’s aim was to determine the effect of hydroalcoholic extract M. cauliflora (HEMC) on vascular tension and blood pressure in rats. In our vitro studies using precontracted isolated aortas from rats, HEMC acetylcholine (positive control) induced relaxation only vessels with endothelium. Pretreatment L-NAME (NO synthase inhibitor) or ODQ (soluble guanylyl cyclase (sGC) abolished HEMC-induced relaxation. The treatment MDL-12,330A (adenylyl (AC) diclofenac (COX reduced vasorelaxation....