A5001944346- Esophageal Cancer Research and Treatment
- Angiogenesis and VEGF in Cancer
- Optical Coherence Tomography Applications
- Photoacoustic and Ultrasonic Imaging
- Nanoplatforms for cancer theranostics
- Pituitary Gland Disorders and Treatments
- Colorectal Cancer Surgical Treatments
- Growth Hormone and Insulin-like Growth Factors
- Cancer Research and Treatments
- Gastrointestinal Bleeding Diagnosis and Treatment
- Coronary Interventions and Diagnostics
- Gastric Cancer Management and Outcomes
- Prosthetics and Rehabilitation Robotics
- Meningioma and schwannoma management
- Anatomy and Medical Technology
- Lung Cancer Diagnosis and Treatment
- Neuroendocrine Tumor Research Advances
- Glioma Diagnosis and Treatment
- Head and Neck Surgical Oncology
- Photodynamic Therapy Research Studies
- Esophageal and GI Pathology
- Optical Imaging and Spectroscopy Techniques
- Biomedical Ethics and Regulation
University Medical Center Groningen
2022-2025
University of Groningen
2022-2024
University of Twente
2021
Klinikum Oldenburg
2014
Abstract Background Patients with cT1-2 colon cancer (CC) have a 10–20% risk of lymph node metastases. Sentinel identification (SLNi) could improve staging and reduce morbidity in future organ-preserving CC surgery. This pilot study aimed to assess safety feasibility robot-assisted fluorescence-guided SLNi using submucosally injected indocyanine green (ICG) patients cT1-2N0M0 CC. Methods Ten consecutive were included this prospective study. Intraoperative submucosal, peritumoral injection...
Significance: Near-infrared fluorescence molecular endoscopy (NIR-FME) is an innovative technique allowing for in vivo visualization of processes hollow organs. Despite its potential clinical translation, NIR-FME still faces challenges, example, the lack consensus performing quality control and standardization procedures systems. This may hamper approval technology by authorities acceptance endoscopists. Until now, several trials using have been performed. However, most these had different...
(1) Introduction: Near-infrared fluorescence (NIRF) combined with tumour-targeted tracers, such as bevacizumab-800CW, could aid surgical decision-making. This study explored the use of IRDye800CW, conjugated to bevacizumab, four commercially available NIRF laparoscopes optimised for indocyanine green (ICG). (2) Methods: A (lymph node) phantom was made from a calibration device and tissue-mimicking material. Serial dilutions bevacizumab-800CW were ICG functioned reference. System settings,...
Abstract Purpose Achieving endocrine remission by gross total resection is challenging in pituitary neuroendocrine tumours (PitNETs) with cavernous sinus invasion. This study aims to assess the safety, feasibility, and optimal dose for intraoperative fluorescence imaging as an added instrument discriminate PitNET from surrounding tissue using bevacizumab-800CW, targeting vascular endothelial growth factor A (VEGF-A). Methods In part I, dose-escalation (0–4∙5-10-25 mg) was performed 4 groups...
In Sierra Leone, access to prostheses is limited due absence of practical knowledge, materials, trained staff, and high cost. This paper investigates the impact a 3D printed prosthesis on health-related quality life (HRQoL) in recipients.Patients with upper extremity amputations were included this case study from December 2018 until July 2019. Data HRQoL was gathered April 2020 Masanga Hospital, central rural Leone. At two follow-up moments assessed by applying standard EQ-5D-5L...
Early detection of (pre)malignant esophageal lesions is critical to improve cancer morbidity and mortality rates. In patients with advanced adenocarcinoma (EAC) who undergo neoadjuvant chemoradiation therapy, the efficacy therapy could be optimized unnecessary surgery prevented by reliable assessment residual tumors after therapy. Optical coherence tomography (OCT) provides structural images at a (sub)-cellular level has potential visualize morphological changes in tissue. However, OCT lacks...
Background: Craniopharyngioma (CP) are the most common sellar tumors in children. Patients often develop excessive weight gain and obesity due to several factors as involvement or damage of hypothalamus. Previous studies on development CP patients have shown an increase before first ten years after diagnosis leading impaired quality life. The long-term these has not been investigated till now.
Barrett's Esophagus (BE) is a common pre-cursor condition to Esophageal Adenocarcinoma (EAC); the monitoring of which can facilitate detection dysplastic tissue, and treatment subsequent early stage EAC. Early EAC improves survival rates significantly. Optical Coherence Tomography low coherence interferometric technique produces depth scans tissues. OCT provides morphological information, but lacks in specificity, so be combined with Near Infrared Fluorescence imaging, also retrieve...