A5077764298- Trace Elements in Health
- Probiotics and Fermented Foods
- Helicobacter pylori-related gastroenterology studies
- Fecal contamination and water quality
- Protein Hydrolysis and Bioactive Peptides
- Bacteriophages and microbial interactions
- Phytochemistry and Bioactive Compounds
- Ion Channels and Receptors
- Adrenal Hormones and Disorders
- Biopolymer Synthesis and Applications
- Meat and Animal Product Quality
- DNA and Nucleic Acid Chemistry
- Polyamine Metabolism and Applications
- Listeria monocytogenes in Food Safety
- Healthcare and Environmental Waste Management
- Gastric Cancer Management and Outcomes
- Genomics and Phylogenetic Studies
- Pesticide Exposure and Toxicity
- Aluminum toxicity and tolerance in plants and animals
- Veterinary medicine and infectious diseases
- Galectins and Cancer Biology
- Water Quality and Pollution Assessment
- Water Treatment and Disinfection
- Gout, Hyperuricemia, Uric Acid
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
Weber State University
2011-2022
University of California, Irvine
1997-2001
VA Sepulveda Ambulatory Care Center
1997
United States Department of Veterans Affairs
1995
University of California, Los Angeles
1993
Low levels of copper in chlorine-free distribution water caused injury coliform populations. Monitoring 44 drinking samples indicated that 64% the population was injured. Physical and chemical parameters were measured, including three heavy metals (Cu, Cd, Pb). Copper concentrations important, ranging from 0.007 to 0.54 mg/liter. Statistical analyses these factors used develop a model predict injury. The predicted almost 90% with concentration near mean observed value (0.158 mg/liter)...
Halophage CW02 infects a Salinivibrio costicola-like bacterium, SA50, isolated from the Great Salt Lake. Following isolation, cultivation, and purification, was characterized by DNA sequencing, mass spectrometry, electron microscopy. A conserved module of structural genes places in T7 supergroup, members which are found diverse aquatic environments, including marine freshwater ecosystems. has morphological similarities to viruses Podoviridae family. The structure CW02, solved cryogenic...
AbstractBackground: The role of neutrophils in experimental colonic damage induced by dextran sulfate sodium is uncertain. We test the hypothesis that are pathogenic significance and anti-neutrophil serum will attenuate oral rats. Methods: Rabbit anti-rat neutrophil Serum (anti-neutrophil serum) or control rabbit was administered to, circulating count monitored in, rats before during feeding regular rat diet for 2 weeks. Histologic features mucosal were evaluated hematoxylin eosin-stained...
Escherichia coli injured by copper in carbonate buffer simulating the drinking water environment showed decreased oxygen utilization. Oxygraph measurements revealed that copper-injured bacteria had a rate of utilization was less than 25% control cells. Respirometry experiments measured rates over longer period time and similar trends. Nuclear magnetic resonanance spectroscopy ( 13 C nmr) gas chromatography were used to identify differences metabolism between healthy populations E. coli. The...
Understanding characteristics that permit survival and growth of Paucilactobacillus wasatchensis as part the nonstarter microbiota cheese is important for minimizing unwanted gas formation in can cause downgrading because slits cracks. The ability Plb. WDC04 to survive pasteurization was studied by inoculating raw milk with 108 cfu/mL measuring after processing through a high-temperature, short-time pasteurizer. Extent rate function pH, salt concentration, presence various organic acids were...
Helicobacter pylori (H. pylori) infection of gastric mucosa is strongly associated with gastritis and peptic ulcer disease. However, the mechanisms ulcerogenic action H. and/or interference healing are unknown. Through binding to its receptor, epidermal growth factor (EGF) accelerates cells migration triggers epithelial cell proliferation which both important for gastroduodenal ulcers. seems interfere healing, but cellular molecular targets these actions have not been elucidated. In present...
Paucilactobacillus wasatchensis can use gluconate (GLCN) as well galactose an energy source and because sodium GLCN be added during salting of Cheddar cheese to reduce calcium lactate crystal formation, our primary objective was determine if the presence in is another risk factor for unwanted gas production leading slits cheese. A secondary calculate amount CO2 produced storage relate this gas-forming substrate that utilized. Ribose promote growth Pa. WDC04 (P.waWDC04) high numbers storage....
Paucilactobacillus wasatchensis, a nonstarter lactic acid bacteria, can cause late gas production and splits cracks in aging cheese when it metabolizes 6-carbon substrates, particularly galactose, to 5-carbon sugar, resulting the release of CO2. Previous studies have not explained no galactose is present. Based on genome sequence Pa. wasatchensis WDC04, genes for potential metabolic pathways were mapped using knowledgebase predictive biology software. This modeling predicted WDC04 could...
Background: Basic fibroblast growth factor has been shown to be mitogenic in colon cancer cell lines. In human malignant melanoma cells, antisense oligodeoxynucleotides targeted against basic messenger RNA significantly inhibit growth. However, the efficacy of such an oligodeoxynucleotide strategy not evaluated for cells. Aim: To investigate whether can stimulate HT‐29 cells and these at baseline. Methods: Western blotting analyses were used confirm presence protein this line. Cell was...
Abstract Background. The pathway by which Helicobacter pylori induces apoptosis in gastric epithelial cells is not known. aim of this study was to determine whether H. ‐induced associated with SAPK/JNK activity human cancer KATO III cells. Materials and Methods. VacA toxin positive strain incubated for 0.5, 1, 2 or 24 hours. protein harvested from the cell lysate precipitation a C‐jun fusion its measured phosphorylation utilizing transblotting phosphoserine antibody. Cellular demonstrated...
ABSTRACT Dextran sulphate sodium (DSS) is an oral agent capable of inducing chronic diarrhoea and colonic inflammation necrosis in rats. The role the afferent nerves this model mucosal damage not known. hypothesis that functional ablation capsaicin‐sensitive will aggravate DSS‐induced rats was tested. Capsaicin pretreatment used to ablate nerve function DSS administered drinking water. Control received vehicle water without DSS. There were significant correlations between score, neutrophil...