Chih‐Chen Lin

ORCID: 0000-0002-6180-4753
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About
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Research Areas
  • Salmonella and Campylobacter epidemiology
  • Diabetes, Cardiovascular Risks, and Lipoproteins
  • Vibrio bacteria research studies
  • Lipid Membrane Structure and Behavior
  • HIV-related health complications and treatments
  • Force Microscopy Techniques and Applications
  • Liver Disease Diagnosis and Treatment
  • Bacteriophages and microbial interactions
  • Antibiotic Resistance in Bacteria
  • Infections and bacterial resistance
  • Viral gastroenteritis research and epidemiology
  • Chemical Synthesis and Analysis
  • Synthetic Organic Chemistry Methods
  • Microscopic Colitis
  • Glycosylation and Glycoproteins Research
  • Microfluidic and Bio-sensing Technologies
  • Antifungal resistance and susceptibility
  • Fungal Infections and Studies
  • Clostridium difficile and Clostridium perfringens research
  • Genomics and Phylogenetic Studies
  • Enterobacteriaceae and Cronobacter Research
  • Microbial Applications in Construction Materials
  • Bacterial biofilms and quorum sensing
  • Antimicrobial Resistance in Staphylococcus
  • Protein purification and stability

Mackay Medical College
2025

Mackay Memorial Hospital
2014-2025

Tamkang University
2010

Multidrug-resistant strains of Citrobacter have emerged, which carry Amp-C β-lactamase (Amp-C), broad-spectrum β-lactamase, extended-spectrum (ESBL), and other resistance mechanisms. These are associated with a higher rate in-hospital mortality. The object this study is to determine the mortality risk factors, susceptibility pattern antibiotics, prevalence genes in patients freundii bacteremia. From January 2009 December 2014, blood isolates C. were collected MacKay Memorial Hospital,...

10.1016/j.jmii.2016.08.016 article EN cc-by-nc-nd Journal of Microbiology Immunology and Infection 2017-06-22

HIV acquisition has been found to be associated with increased risk of cardiometabolic syndrome in the past. In this study, we attempt delineate factors metabolic among persons living a single medical center Taiwan using mostly integrase inhibitors-based regimen as HAART. A cross-sectional study involving all people (PLWH) aged ≥ 18 years who visited MacKay Memorial Hospital, Taipei, between September 7, 2022 January 31, 2023 was performed. modified National Cholesterol Education Program ATP...

10.1038/s41598-025-88552-w article EN cc-by-nc-nd Scientific Reports 2025-02-07

A surface plasmon resonance (SPR) biosensor technology has recently been applied biochemically and clinically to the study of immunologic recognition evaluation binding parameters for various interactions between antibodies (Abs) antigens (Ags) at liquid-solid interface. The simple interaction hapten Ab fragment, e.g., variable single-chain fragment antigenbinding can be described sufficiently by a 1:1 stoichiometry in SPR. However, determination constant an anti-protein is usually...

10.2174/157016406780655586 article EN Current Proteomics 2006-12-01

There are few attempts at diagnosis among physicians who pay less attention to Clostridiodes difficile infection (CDI) and think that one-step enzyme immunoassay (EIA) toxin tests anaerobic cultures untrustworthy. This study investigated patients had loose stool more than 3 times/day after admission from April 2016 January 2017. We replaced the rapid test culture with a two-step of glutamate dehydrogenase (GDH) toxins, we optimized process microbiology culture. PCR for genes (tcdA tcdB)...

10.1016/j.jmii.2019.08.004 article EN cc-by-nc-nd Journal of Microbiology Immunology and Infection 2019-09-28

Abstract Lewis acid, Me 3 SiOTf, has been shown to be a promising promoter for aza‐Michael reaction of relatively acidic primary amide with α,β‐unsaturated ketone. A sries ketones was transformed their corresponding β‐amido moderate yields under this condition.

10.1002/jccs.201000110 article EN Journal of the Chinese Chemical Society 2010-08-01

The purpose of this study is to describe clinical characteristics Salmonella bacteremia in adult patients and analyze ciprofloxacin-nonsusceptible isolates. A total 101 blood isolates from were collected January 2011 December 2013 MacKay Memorial Hospital. Eight screened for carbapenemase other β lactamase genes. Isolates examined by PCR the quinolone resistance-determining region (QRDR) all subunits DNA gyrase (gyrA gyrB) genes topoisomerase IV (parC parE) There 22 (21.78%) S. enterica...

10.1016/j.jmii.2015.09.001 article EN cc-by-nc-nd Journal of Microbiology Immunology and Infection 2015-09-11

<title>Abstract</title> Background HIV acquisition has been found to be associated with increased risk of cardiometabolic syndrome in the past. In this study, we attempt delineate factors metabolic among persons living a single medical center Taiwan using mostly integrase inhibitors-based regimen as HAART. Methods A cross-sectional study involving all people live (PLWH) aged ≥ 18 years who visited MacKay Memorial Hospital, Taipei, between September 7, 2022 January 31, 2023 was included....

10.21203/rs.3.rs-4817270/v1 preprint EN Research Square (Research Square) 2024-09-18

Abstract The product and direct role of the rssC gene Serratia marcescens is unknown. For unraveling gene, atomic force microscopy has been used to identify surfaces intact S. wild-type CH-1 cells mutant CH-1ΔC cells. detailed surface topographies were directly visualized, quantitative measurements physical properties membrane structures provided. observed before after treatment with lysozyme, their topography-related parameters, e.g., a valley-to-peak distance, mean height, roughness,...

10.1017/s1431927610093943 article EN Microscopy and Microanalysis 2010-10-20

Abstract Background Elizabethkingia species are antibiotic-resistant microbes. It is a serious bacterial pathogen that can cause the patient to die. Thanks technology of sequencing, we identify different strains species. The genus currently comprises 6 species, E. meningoseptica, miricola, anophelis, bruuniana, ursingii and occul. In previous study in Taiwan, meningoseptica was major strain caused infection from 2009 2016. But another reference, found anophelis became dominant other...

10.1093/jacamr/dlac133.019 article EN cc-by JAC-Antimicrobial Resistance 2023-01-19

In Taiwan between 1987 and 1996, 45 sporadic cases of Salmonella paratyphi A were detected. The majority cases, a total 24, occurred in the year thus accounting for 53% all cases. 33 (73%) imported; 8 (18%) local cases; 4 (9%) unknown origin. Most imported infected Southeast Asia: 31% Thailand, 27% Indonesia, 7% on mainland China, 2% each Singapore, Malaysia, Cambodia, Myanmar. pathogenic agents 37 (82.2%) detected by blood culture, 6 (5 carriers) (13.3%) from feces, one (2.2%) bile bone...

10.6525/teb.200004_16(4).0001 article EN Epidemiology bulletin 2000-04-01
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