A5080187649- Mosquito-borne diseases and control
- Cancer-related molecular mechanisms research
- Viral Infections and Vectors
- COVID-19 epidemiological studies
- SARS-CoV-2 detection and testing
- Tuberculosis Research and Epidemiology
- MicroRNA in disease regulation
- Malaria Research and Control
- Vibrio bacteria research studies
- Cardiac Ischemia and Reperfusion
- Immune Response and Inflammation
- Biosensors and Analytical Detection
- SARS-CoV-2 and COVID-19 Research
- Birth, Development, and Health
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Anesthesia and Neurotoxicity Research
- Ginger and Zingiberaceae research
- CRISPR and Genetic Engineering
- Pneumonia and Respiratory Infections
- Reproductive System and Pregnancy
- Machine Learning in Bioinformatics
- Colorectal and Anal Carcinomas
- COVID-19 diagnosis using AI
- Autophagy in Disease and Therapy
- Impulse Buying and Technology Impacts
Central China Normal University
2024
Anhui Provincial Hospital
2024
Guangzhou Medical University
2021-2023
Pennsylvania State University
2023
Third Affiliated Hospital of Guangzhou Medical University
2021-2023
Chongqing Medical University
2023
Chongqing Public Health Medical Center
2023
Community Health Center
2023
Guangzhou University of Chinese Medicine
2019-2022
Jinan University
2022
Spinal cord injury (SCI), including immediate mechanical and secondary injury, is associated with the inflammatory response, apoptosis oxidative stress in response to traumatic injury. Tanshinone IIA (TIIA) one of major extracts obtained from Salvia miltiorrhiza BUNGE, which has anti-inflammatory anti-apoptotic effects on many diseases. However, little known about TIIA treatment SCI. Therefore, aim present study evaluate pharmacological action damage underlying mechanisms experimental SCI rats.
Breast cancer is one of the leading causes cancer-associated mortality in women worldwide and has become a major public health problem. Although definitive cause breast not known, many genes sensitive to have been detected using advanced technologies. Our study identified 3301 differentially expressed lncRNAs mRNAs between tumor normal samples from The Cancer Genome Atlas database. Based on gene expression analysis clinical traits as well weighted co-expression network analysis, Brown module...
Abstract Background To contain the outbreak of coronavirus disease 2019 (COVID-19) in China, many unprecedented intervention measures are adopted by government. However, these may interfere normal medical service. We sought to model trend COVID-19 and estimate restoration operational capability metropolitan service China. Methods Real-time data population mobility were extracted from open sources. SEIR (Susceptible, Exposed, Infectious, Recovered) neural network models (NNs) built trends...
Background/Aims: Obesity-related kidney disease is associated with elevated levels of saturated free fatty acids (SFA). SFA lipotoxicity in tubular cells contributes to significant cellular apoptosis and injury. Salvianolic acid B (SalB) the most abundant bioactive molecule from Radix Salviae Miltiorrhizae. In this study, we investigated effect SalB on SFA-induced renal injury endoplasmic reticulum (ER) stress, vivo vitro . Methods: C57BL/6 mice were assigned five groups: a control group...
There is currently no drug or therapy that can cure the coronavirus disease 2019 (COVID-19), which highly contagious and be life-threatening in severe cases. Therefore, seeking potential effective therapies an urgent task. An older female at Leishenshan Hospital Wuhan, China, with a case of COVID-19 significant shortness breath decrease peripheral oxygen saturation (SpO2), was treated using manual acupuncture Chinese herbal medicine granule formula Fuzheng Rescue Lung Xuebijing Injection...
Dengue fever virus (DENV) is a global health threat that becoming increasingly critical. However, the pathogenesis of dengue has not yet been fully elucidated. In this study, we employed bioinformatics analysis to identify potential biomarkers related and clarify their underlying mechanisms. The results showed there were 668, 1901, 8283 differentially expressed genes between dengue-infected samples normal in GSE28405, GSE38246, GSE51808 datasets, respectively. Through overlapping, total 69...
Cerebral malaria (CM) is a manifestation of caused by plasmodium infection. It has high mortality rate and severe neurological sequelae, existing significant research gap requiring further study at the molecular level.We downloaded GSE117613 dataset from Gene Expression Omnibus (GEO) database to determine differentially expressed genes (DEGs) between CM group control group. Weighted gene coexpression network analysis (WGCNA) was applied select module hub most relevant CM. The common key DEGs...
At the height of COVID-19 pandemic, K-12 schools struggled to safely operate under fast-changing pandemic situation. However, little is known about impact different school operating scenarios considering ongoing efforts vaccination. In this study, we deployed an agent-based simulation model mimic disease transmission in a mid-sized community consisting 10,000 households. A total eight were simulated, decreasing order restrictiveness regarding mitigation measures. When masks worn at school,...
ABSTRACTThe COVID-19 pandemic and measures against it provided a unique opportunity to understand the transmission of other infectious diseases evaluate efficacy prevention on them. Here we show dengue epidemic in Yunnan, China, during was dramatically reduced compared non-pandemic years and, importantly, spread confined only one city, Ruili. Three key features characterized this outbreak: (i) urban-to-suburban efficiently blocked; (ii) scale urban region less affected; (iii) co-circulation...
Insulin resistance, a pathological response to insulin hormone in insulin-dependent cells, is characterized by the presence of high glucose and concentrations. The homeostasis model resistance (HOMA-IR) one most used indexes estimate assessing fasting levels. An association was observed between vitamin D levels which varied different ethnic groups, there some evidence that supplementation could contribute improvement resistance. This study assessed 25-hydroxyvitamin (25[OH]D) concentration...
Lower-grade gliomas (LGG) are the most common intracranial malignancies that readily evolve to high-grade and increase drug resistance. Paraptosis is defined as a nonapoptotic form of programmed cell death, which gradually focused on patients with develop treatment options. However, specific role paraptosis in LGG its correlation still vague. In this study, we first establish novel paraptosis-based prognostic model for patients. The relevant data were acquired from Cancer Genome Atlas...
Opportunistic Candida species causes severe infections when the human immune system is weakened, leading to high mortality.In our study, bioinformatics analysis was used study high-throughput sequencing data of samples infected with four kinds species. And hub genes were obtained by statistical analysis.A total 547, 422, 415 and 405 differentially expressed (DEGs) albicans, glabrata, parapsilosis tropicalis groups obtained, respectively. A 216 DEGs after taking intersections from groups....
We aimed to examine the associations between cord blood lipids and childhood adiposity investigate whether these vary across birth weight categories (small for gestational age (SGA), appropriate (AGA) large (LGA)) in 1306 infants Born Guangzhou Cohort Study, China. Adiposity outcomes at of three years included z-scores weight-for-length/height (WFLZ), body mass index (BMIZ), subscapular (SSTZ) triceps skinfold thickness (TSTZ), sum thicknesses (SSFTZ). Cord triglycerides (TG) levels were...
<title>Abstract</title> Objective To evaluate the clinical efficacy of conbercept combined with micropulse laser(MPL) in treating polypoidal choroidal vasculopathy (PCV). Methods In this prospective, randomized controlled trial conducted from February 2023 to April 2024, 52 patients (52eyes) PCV at ### hospital were enrolled. Participants into a monotherapy group (27cases, 27eyes) and combination treatment (conbercept plus laser(MPL); 25cases, 25eyes). After an initial series three...