A5004936379- Nanoparticle-Based Drug Delivery
- Graphene and Nanomaterials Applications
- Curcumin's Biomedical Applications
- Wastewater Treatment and Nitrogen Removal
- Nanoparticles: synthesis and applications
- Lanthanide and Transition Metal Complexes
- Drug-Induced Hepatotoxicity and Protection
- Microbial Community Ecology and Physiology
- Nanoplatforms for cancer theranostics
- Magnetic Properties and Synthesis of Ferrites
- Liver Disease Diagnosis and Treatment
- Polymer Nanocomposite Synthesis and Irradiation
- Constructed Wetlands for Wastewater Treatment
- Geochemistry and Elemental Analysis
- Membrane Separation Technologies
- Cholinesterase and Neurodegenerative Diseases
- Optical Imaging and Spectroscopy Techniques
- Polymer-Based Agricultural Enhancements
- Pharmacological Effects of Medicinal Plants
- Aquatic life and conservation
- Electromagnetic wave absorption materials
- Inhalation and Respiratory Drug Delivery
- Natural Antidiabetic Agents Studies
- Microplastics and Plastic Pollution
- Advanced Drug Delivery Systems
Vietnam Academy of Science and Technology
2019-2025
Institute of Materials Science
2024
Vietnam National University, Hanoi
2017
Curcuma longa, which contains curcumin as a major constituent, has been shown many pharmacological effects, but it is limited using in clinical due to low bioavailability. In this study, we developed phytosome formulation and evaluated the hepatoprotective effect of on paracetamol induced liver damage mice. Phytosome (equivalent 100 200 mg/kg body weight) (200 were given by gastrically toxicity was (500 mg/kg) during 7 days. On final day animals sacrificed function markers (ALT, AST),...
Fe 3 O 4 and Dox do not affect the fluorescence of Cyanine 5.5 A3 conjugate can be effectively used in MR NIR-fluorescence tumor imaging.
The combination of AgNPs and plant extracts provides synergic antibacterial effect on various E. coli strains.
Advanced bioremediation agent in treating aquaculture water: Multilayer immobilizing denitrifying bacteria and TiO 2 –AgNPs onto expanded clay.
The study of nanotechnology has been focused in recent years on the application various fields including agriculture. Nanofertilizers were suggested to have ability supply plants with nutrients more effectively and thus significantly improve crop productivity. Previous studies reported fabrication nanofertilizers that contained only one or two essential elements. addition other is necessary for promoting plant development. Therefore, this study, a novel integrated nanofertilizer containing...
Abstract The overuse of antibiotics has led to the sharp increase antibiotic‐resistant bacteria that can consequently transmit and cause hard‐to‐cure human diseases. To deal with this problem, nano drug delivery systems have been widely researched. This report focuses on developing an Alginate/Chitosan‐based nanosystem carried simultaneously Doxycycline (DOX), Florfenicol (FLO), silver nanoparticles (AgNPs). optimal Alginate/Chitosan ratio 3 : 2 (w/w) created most stable nanocarrier system....
Nowadays, the raising in agriculture productions is required to meet demand for growing population. Besides macronutrients (nitrogen, phosphorus and potassium, a lesser degree, calcium, sulfur magnesium) requirements, plants need micronutrients (copper, iron, zinc, boron...) ensure productivity as well high agricultural quality. The activity of these elements greatly affected by very small changes environmental factors such pH, mechanical composition organic matter soil. Therefore, there...
Abstract The in vivo imaging of the drug distribution during cancer treatment plays an important role helping physicians and pharmacists to monitor progress improve effectiveness therapy. Our goal this work was prepare a multifunctional nano delivery system that not only co‐loaded iron oxide nanoparticles (Fe 3 O 4 NPs) Doxorubicin (Dox) but also attached near‐infrared fluorescent agent Cyanine 5.5 based on poly(lactide)‐tocopheryl polyethylene glycol 1000 succinate (PLA‐TPGS) copolymer....
Curcumin has been shown to possess strong cytotoxic effect against various cancer cell lines. However, curcumin not applied as a drug for treatment of yet due low solubility in water and bioavailability. The aims this study were prepare new polyethylene glycol (PEG) conjugated evaluate its antitumor activity vitro.PEG-CUR was prepared by the reaction between PEG. PEG-CUR which characterized SEM, TEM, FTIR, DSC 1H NMR analysis. physicochemical parameters such zeta potential, size...
The combination of magnetic resonance imaging (MRI)/near‐infrared (NIR) fluorescence signals and chemotherapy agents has been developed for cancer diagnosis treatment. In this work, we investigated the impacts NIR Cyanine 5.5 Doxorubicin on cell cycle arrest, resonance, optical Fe3O4‐encapsulated nanosystems based poly(lactide)‐tocopheryl polyethylene glycol succinate (PLA‐TPGS) copolymer. Although Fe3O4 nanoparticles (NPs) are less cytotoxic than Doxorubicin, they present a cytostatic...
The developed nanosystem could be an effective cancer drug deliverer, MRI contrast enhancer and near infrared fluorescent probe.
The multifunctional nano drug delivery system (MNDDS) has much revolutionized in cancer treatment, aiming to eliminate many disadvantages of conventional formulations. This paper herein proposes and demonstrates MNDDS inspired by poly(lactide)-tocopheryl polyethylene glycol succinate (PLA-TPGS) copolymer co-loaded Doxorubicin magnetic iron oxide nanoparticles (MIONs) with a 1 : (w/w) optimal ratio. In vitro release kinetics from this nanosystem fitted best the Weibull kinetic model can be...
Acetylcholinesterase (AChE) is a key target in the treatment of Alzheimer’s disease. Principal role AChE hydrolyzes neurotransmiter acetylcholine. Medicinal plants are potential source inhibitors. In this study, we studied inhibitory activities extraction Mahonia nepalensis. This medicianl plant was extracted with ethanol 96% and subsequently fractionated n-hexane, ethyl acetate (EtOA) n-butanol (n-BuOH) solvents. These fractions were evaluated activity by Ellman’s colorimetric method....
In this study, we examined the dependence of fluorescent intensity on different factors in synthesis process Fe3O4-cyanine 5.5 nanoparticles. The results showed that Fe3O4 nanoparticles needed to be covered with a layer NH2 group before reacting cyanine 5.5-NHS ester. best NHS ester:Fe3O4 and ester :APTES ratios were 1:20 1:3, respectively. drug delivery did not affect much property while increasing excitation wavelength could lead increase system.