A5025480173- Fibromyalgia and Chronic Fatigue Syndrome Research
- Diverse Scientific Research Studies
- Musculoskeletal pain and rehabilitation
- T-cell and B-cell Immunology
- Ophthalmology and Visual Health Research
- Pneumonia and Respiratory Infections
- Spinal Dysraphism and Malformations
- COVID-19 Clinical Research Studies
- Infective Endocarditis Diagnosis and Management
- Diabetes Management and Research
- Viral Infections and Outbreaks Research
- Acute Ischemic Stroke Management
- Scoliosis diagnosis and treatment
- Iron Metabolism and Disorders
- Global Maternal and Child Health
- Systemic Lupus Erythematosus Research
- Pericarditis and Cardiac Tamponade
- Hemoglobinopathies and Related Disorders
- Pharmaceutical Practices and Patient Outcomes
- Respiratory viral infections research
- Immune responses and vaccinations
- Artificial Intelligence in Healthcare
- Neurogenetic and Muscular Disorders Research
- Viral Infections and Immunology Research
- Otitis Media and Relapsing Polychondritis
Irrua Specialist Teaching Hospital
2021-2024
Ambrose Alli University
2021-2024
University of Science and Technology of Benin
2021
Abstract Infection with Lassa virus (LASV) can cause fever, a haemorrhagic illness an estimated fatality rate of 29.7%, but causes no or mild symptoms in many individuals. Here, to investigate whether human genetic variation underlies the heterogeneity LASV infection, we carried out genome-wide association studies (GWAS) as well seroprevalence surveys, leukocyte antigen typing and high-throughput variant functional characterization assays. We analysed fever susceptibility fatal outcomes 533...
Systemic lupus erythematosus (SLE) is a condition that manifests in variety of ways. Although pericarditis and pericardial effusion are frequent cardiac manifestations SLE, tamponade rarely reported, especially as the initial manifestation disease. We describe 38-year-old Nigerian lady who presented with three months progressive dyspnea. She had intermittent fever, tachycardia, tachypnea, hypotension, jugular vein distension, muffled heart sounds. Echocardiography confirmed tamponade. The...
Low back pain (LBP) is a prevalent musculoskeletal condition that poses significant public health challenges. However, its epidemiology in Sub-Saharan Africa, especially rural settings, remains largely unexplored. This study aimed to determine the of LBP Nigerian Teaching Hospital.This was retrospective review records all cases seen at rheumatology clinic from 2018 2022 Hospital South-South Nigeria. The sociodemographic and clinical data, including disability scores, extracted patients'...
Systemic lupus erythematosus (SLE) is an autoimmune disorder with a poorly understood aetiology. It predominantly affects females and has variety of clinical manifestations. In Nigeria, there are limited data on the prevalence burden disease. This study aimed to determine laboratory profiles SLE patients seen in new rheumatology clinic South-South Nigeria.This was retrospective cross-sectional conducted over five years (January 2016 December 2020). The case files that satisfied diagnosis...
Fibromyalgia is a chronic pain syndrome of unknown etiology characterized by widespread musculoskeletal and tenderness. It affects the quality life patients has been associated with human immunodeficiency virus (HIV). The study aimed to determine prevalence fibromyalgia in HIV-positive assess effect on their functional status.This was cross-sectional comprising 160 treatment-naive age- sex-matched HIV-negative controls. diagnosis based 2011 modification 2010 American College Rheumatology...
Background: Fibromyalgia is not an uncommon cause of chronic musculoskeletal pain, and despite its rising prevalence, it remains a diagnostic challenge for physicians. This study aimed to assess the knowledge awareness fibromyalgia among Nigerian physicians.Methods: was cross-sectional, self-reported online survey. A total 502 physicians participated in study. The data collected using semi-structured questionnaire. questionnaire comprised sociodemographic questions related fibromyalgia....
BACKGROUND
 Despite the increasing prevalence of fibromyalgia, there has been little or no attention to its diagnosis and treatment in undergraduate medical curriculum. This study intended assess knowledge awareness fibromyalgia among students Nigeria.
 METHODS
 was a cross-sectional, descriptive survey conducted from September December 2021. A total 175 clinical participated survey. The questionnaire comprised sociodemographic data questions related fibromyalgia. scoring...
Background: Malaria is a public health concern deeply ingrained within local communities in sub-Saharan Africa. Local beliefs and practices play critical role defining the effectiveness of control measures. This study aimed to assess knowledge, attitudes, regarding malaria rural community South-South Nigeria. Methods: cross-sectional was conducted Ugun Data were collected from participants using an interviewer-administered questionnaire. analysis performed SPSS P-value < 0.05 considered...
Objective: This study aimed to determine the prevalence, distribution, and treatment outcomes of tuberculosis (TB) in a rural hospital Nigeria.
 Methods: was retrospective cross-sectional conducted between 2013 2022. The data on all patients diagnosed with TB during period were collected from hospital's registry. then entered into SPSS for analysis. level statistical significance set at P < 0.05.
 Results: overall prevalence among suspects 41.3%. Pulmonary most common form TB,...
Introduction Sickle cell anemia (SCA) in adults has many clinical manifestations. These manifestations are due to effects of recurrent hemolysis, anemia, and ischemia-reperfusion injury on various organs, including the heart. factors determine severity disease. Objectives The aim study was assess SCA using a scoring system consisting laboratory parameters. In addition, aimed electrocardiographic abnormalities adult population. Study design This cross-sectional, observational conducted...
BACKGROUNDThe metabolic profile which includes glycated haemoglobin, insulin resistance, pancreatic beta cell function and lipid is frequently deranged in acute ischaemic stroke. Stroke a leading cause of death worldwide an emerging long-term disability mortality Africa. Our study aimed to determine the correlation between stroke rural Hospital Southern Nigeria.METHODOLOGYThis was prospective cross-sectional study. Fifty consecutive first-ever patients presenting within 72 hours were matched...
Aim: This study aimed to assess the knowledge of coronavirus disease 2019 (COVID-19) and perception care among diabetes mellitus patients during COVID-19 pandemic.
 Methods: was a cross-sectional 173 over 12 weeks in endocrinology outpatient clinic. An interviewer-administered questionnaire used acquire data on socio-demographic clinical characteristics, as well questions care. The acquired were analyzed using SPSS, p-value less than 0.05 considered significant.
 Results: A total...
Adult-Onset Still’s Disease (AOSD) is an uncommon multisystemic inflammatory disease of no known aetiology.1 Bywaters in 1971 was the first to describe this clinical entity.2,3 Its estimated annual incidence 0.16 per 100,000 persons.4 AOSD has a bimodal pattern age distribution with peaks at 15 - 25 and 36 46 years. This shows that young adults are mainly affected. 4 It characterised by daily high spiking fever, evanescent salmon coloured rash, polyarthritis, leucocytosis, negative...
Systemic lupus erythematosus and syringomyelia are two distinct conditions with different pathogenetic pathways as well diverse genetic clinical characteristics. The coexistence of these has not been previously documented in the literature. We describe a 38-year-old male who presented progressive bilateral weakness pain lower limbs loss sphincteric functions three years following diagnosis nephritis. Relevant autoantibody testing, hypocomplementemia, biopsy-proven membranous nephritis...