- HIV/AIDS Research and Interventions
- SARS-CoV-2 and COVID-19 Research
- COVID-19 Clinical Research Studies
- Breastfeeding Practices and Influences
- HIV-related health complications and treatments
- Poxvirus research and outbreaks
- Bacillus and Francisella bacterial research
- Immunotherapy and Immune Responses
- Syphilis Diagnosis and Treatment
- Family and Patient Care in Intensive Care Units
- Palliative Care and End-of-Life Issues
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Female Genital Mutilation/Cutting Issues
- HIV/AIDS drug development and treatment
- Hemodynamic Monitoring and Therapy
- Reproductive tract infections research
- Childhood Cancer Survivors' Quality of Life
- Zoonotic diseases and public health
- Health Sciences Research and Education
- Stroke Rehabilitation and Recovery
- Geriatric Care and Nursing Homes
- Acute Ischemic Stroke Management
- Viral Infections and Outbreaks Research
- Intensive Care Unit Cognitive Disorders
- Sepsis Diagnosis and Treatment
National Institute of Allergy and Infectious Diseases
2024-2025
National Institutes of Health
2024-2025
University of North Carolina at Chapel Hill
2024
Florey Institute of Neuroscience and Mental Health
2016
Monash Health
2016
Monash University
2016
La Trobe University
2016
Eastern Health
2016
University of Glasgow
2016
Deakin University
2016
Bivalent COVID vaccines containing mRNA for ancestral and Omicron BA.5 spike proteins do not induce stronger T cell responses to than monovalent that contain only mRNA. The reasons this finding have been elucidated. Here, we show healthy donors (HDs) people living with HIV (PLWH) on antiretroviral therapy mostly target epitopes are affected by mutations. We use the functional expansion of specific cells (FEST) assay determine percentage CD4+ cross-recognize both those monoreactive each...
Autoantibodies (AAbs) to interferon alpha, nuclear antigens, cardiolipin, and beta 2 glycoprotein 1, have been associated with COVID-19 severity. Despite relatively low morbidity mortality in East Central Africa, AAb prevalence these populations remain understudied. We evaluated seroprevalence 155 Ugandans, aged 40-50, using paired samples collected before after the onset of pandemic. Among these, 117 had serological evidence SARS-CoV-2 infection, 38 did not. To assess effect infection on...
The aim of this paper is to describe the emerging role palliative care clinical trials nurse in an era evidence-based practice and increasing trial activity settings across Australia. An overview current work provided, with a focus on three aspects nursing that have significant implications for patients: managing consent process, integrating into multidisciplinary care, establishing building evidence base inform settings. Clinical roles provide nurses opportunity contribute research, help...
Rapid HIV tests are critical to surveillance and universal testing treatment programs. We assessed longitudinal patterns in indeterminate rapid test results an African population-based cohort. Prospective antibody results, defined by two parallel tests, among participants aged 15-49 years from three survey rounds of the Rakai Community Cohort Study, Uganda, 2013 2018, were assessed. An result was as any weak positive or when one negative other positive. A total 31,405 contributed 54,459...
Background: Since July 23, 2022, global mpox cases reached 92,546, with over 31,000 in the United States. Asymptomatic carriage is a critical mechanism influencing dissemination of mpox. Seroprevalence studies are crucial for determining epidemic's true burden, but uncertainties persist serologic assay performance and how smallpox vaccination may influence interpretation. Objectives: Our study aimed to assess several diagnostic assays among mpox-positive, vaccinated, pre-outbreak negative...
Syphilis diagnosis in the emergency department (ED) setting is often missed due to lack of ED-specific testing strategies. We characterized ED patients with high-titer syphilis infections (HTSIs) goal defining a screening strategy that most parsimoniously identifies undiagnosed, untreated infections. Unlinked, de-identified remnant serum samples from attending an urban ED, between 10 January and 9 February 2022, were tested using three-tier algorithm, sociodemographic variables extracted...
Since July 23, 2022, global mpox cases reached 92,546, with over 31,000 in the United States. Asymptomatic carriage is a critical mechanism influencing dissemination of mpox. Seroprevalence studies are crucial for determining epidemic's true burden, but uncertainties persist serologic assay performance and how smallpox vaccination may influence interpretation.