A5069071086- Neonatal and fetal brain pathology
- Ovarian cancer diagnosis and treatment
- Endometriosis Research and Treatment
- Phonocardiography and Auscultation Techniques
- Inflammatory mediators and NSAID effects
- Cancer, Stress, Anesthesia, and Immune Response
- Intraperitoneal and Appendiceal Malignancies
- Protease and Inhibitor Mechanisms
- Gestational Diabetes Research and Management
- Drug Transport and Resistance Mechanisms
- Eicosanoids and Hypertension Pharmacology
- Pregnancy-related medical research
- Pediatric Hepatobiliary Diseases and Treatments
- Endometrial and Cervical Cancer Treatments
- Redox biology and oxidative stress
- Pregnancy and preeclampsia studies
- Nursing Roles and Practices
- Bariatric Surgery and Outcomes
- Non-Invasive Vital Sign Monitoring
- Pharmacological Receptor Mechanisms and Effects
- Chemokine receptors and signaling
- Economic and Financial Impacts of Cancer
- NF-κB Signaling Pathways
- Parvovirus B19 Infection Studies
- Neonatal Respiratory Health Research
Medical University of Warsaw
2012-2025
Abstract Purpose: The unique mechanism of tumor destruction by photodynamic therapy (PDT), resulting from apoptotic and necrotic killing cells accompanied local inflammatory reaction induction heat shock proteins (HSPs), prompted us to investigate the antitumor effectiveness combination PDT with administration immature dendritic (DCs). Experimental Design: Confocal microscopy Western blotting were used influence on apoptosis expression HSP in C-26 cells. flow cytometry studies examine...
The purpose of this study was to determine if asiatic acid may act efficiently in the model cyclophosphamide (CYP)-induced cystitis rats. We performed experiments after administration CYP (single dose 200 mg/kg, intraperitoneally), (30 mg/kg/day for 14 consecutive days, by oral gavage), or plus acid, during which conscious cystometry, measurements urothelium thickness and bladder edema, as well selected biomarkers analyses were conducted. In rats that received together with CYP, a drop basal...
The surgical treatment of patients with advanced-stage ovarian cancer is based on maximal cytoreduction widening the debulking extra-ovarian tissues and infiltrated organs. purpose study was to assess outcome after optimal partial bowel resection find risk factors relapse. Another goal quantitative qualitative assessment intra- postoperative complications in studied group. analysis procedures intestinal period 33 patients, International Federation Gynecology Obstetrics (FIGO) stages III IV,...
An increasing body of evidence from both academic and clinical studies shows that time-of-day exposure to antigens might significantly alter modulate the development adaptive immune responses. Considering immense impact COVID-19 pandemic on global health diminished efficacy vaccination in selected populations, such as older immunocompromised patients, it is critical search for most optimal conditions mounting responses against SARS-CoV-2. Hence, we conducted an observational study 435...
Peroxiredoxin-1 (PRDX-1) belongs to a family of antioxidant enzymes and has proved be versatile molecule regulating cell growth, differentiation apoptosis. PRDX1-regulated signaling pathways play an important role in the progression metastasis human tumours, especially breast, esophageal lung cancers. The aim study was evaluate expression PRDX-1 ovarian cancer tissues, test clinical value as prognostic factor this malignancy.PRDX-1 assessed by automated immunohistochemistry tumours taken...
In gestational diabetes mellitus (GDM) abnormal glucose metabolism normalizes soon after delivery. However, the history of GDM predisposes to carbohydrate intolerance in future. The aim study was explore risk factors and evaluate women with a GDM.155 patients entered this case-control study. Participants fulfilled inclusion criteria: GDM, perinatal care center. Medical family laboratory findings were analyzed. Oral tolerance test (OGTT) performed.18.1% presented impaired fasting during...
Objectives: Peroxiredoxins (PRDXs) constitute a family of antioxidant enzymes which are also involved in the process carcinogenesis. They composed six identified isoforms (PRDX-1-6) and supposed to play different roles tumor progression, depending on type cancer member PRDX family. The aim study was assess prog- nostic value PRDXs ovarian cancer. Material methods: dataset patients with from Cancer Genome Atlas analyzed. Expression PRDX-1 6 mRNA evaluated 260 samples. prognostic assessed...
We report a case of 21-year-old pregnant woman with an early onset intrahepatic cholestasis pregnancy very high aminotransferases activity and bilirubin concentration. Viral autoimmune hepatitis, other possible causes liver function impairment were excluded. Treatment ursodeoxycholic acid improved biochemical markers. The patient delivered healthy female neonate by caesarean section. Neonatal postoperative courses uneventful.
Objectives: Tissue plasminogen activator (tPA) is a key enzyme for fibrin degradation and the proteolytic defense against formation of thrombotic endothelial deposits. tPA involved in carcinogenesis but its exact role tumor biology not very well understood prognostic value remains ambiguous different cancers. The aim study was to assess plasma patients with epithelial ovarian cancer (EOC) course first line chemotherapy. Material methods: covered 60 EOC who underwent 1st Plasma assessed at...
Background: Cytomegalovirus (CMV) infection represents a major issue worldwide, since it constitutes the most common viral congenital infection, with prevalence of 0.58% and 1–5% in developed developing countries, respectively. According to recent studies, prenatal treatment significantly decreases risk vertical CMV transmission, early intervention may even prevent termination pregnancy. This study aimed investigate level awareness among pregnant patients through semi-systematic review....
Purpose Primary fallopian tube carcinoma (PFTC) is the rarest form of female genital malignancy. The imaging applied for suspected adnexal masses includes transvaginal ultrasound (US), computed tomography (CT), and magnetic resonance (MRI), but vast majority PFTC recognised intraoperatively. Material methods study group consisted seven women with postoperatively histopathological diagnosis PFTC. To recognise characteristic findings PFTC, retrospective analysis preoperative MRI was performed....