A5054116007- Bone Metabolism and Diseases
- Heavy metals in environment
- Environmental Toxicology and Ecotoxicology
- Rheumatoid Arthritis Research and Therapies
- Cancer Immunotherapy and Biomarkers
- Immune Cell Function and Interaction
- Gene expression and cancer classification
- HER2/EGFR in Cancer Research
- T-cell and B-cell Immunology
- Mercury impact and mitigation studies
- Acute Lymphoblastic Leukemia research
- Aquaculture Nutrition and Growth
- Cancer Genomics and Diagnostics
- Osteoarthritis Treatment and Mechanisms
- Healthcare and Environmental Waste Management
- Molecular Biology Techniques and Applications
- Inflammatory mediators and NSAID effects
- TGF-β signaling in diseases
- Systemic Lupus Erythematosus Research
- RNA Research and Splicing
- Autoimmune and Inflammatory Disorders Research
Veer Bahadur Singh Purvanchal University
2024
Chhatrapati Shahu Ji Maharaj University
2015-2021
Patient-Centered Outcomes Research Institute
2021
In the phase III IMpassion130 trial, combining atezolizumab with first-line nanoparticle albumin-bound-paclitaxel for advanced triple-negative breast cancer (aTNBC) showed a statistically significant progression-free survival (PFS) benefit in intention-to-treat (ITT) and programmed death-ligand 1 (PD-L1)-positive populations, clinically meaningful overall (OS) effect PD-L1-positive aTNBC. The KEYNOTE-355 trial adding pembrolizumab to chemotherapy aTNBC similar PFS effects. IMpassion131...
Background: Rheumatoid arthritis is an immunologically driven chronic synovitis showing heterogeneity in disease progression, treatment, and variability of response to therapy. This study investigated the effectiveness methotrexate, folic acid, vitamin C for treatment patients with rheumatoid arthritis. Methods: The effects methotrexate C, occasional steroid were analyzed 62 selected on basis American College Rheumatology (ACR) criteria, before after 24 wk therapy (1) lipoprotein profile,...
Present study has been planned to observe the effect of Cadmium chloride on locally available economically important edible fish _Channa punctatus _(body weight 27.04±0.19 g and length 16.7±0.20 cm). To assess cadmium in terms enzymatic non-enzymatic assays, laboratory studies have done. Fish were acclimatized treated separately with concentrations 35 mg/L 70 CdCl2. The livers dissected out homogenized 0.1 M sodium phosphate buffer (pH 7.4). Biochemical analyses done for lipid peroxidation,...
Aquatic ecosystem of India is being affected by various heavy metals. In present, cadmium contamination in aquatic organism as well its accumulation food chain has become a global environmental concern. Cadmium exposure to fishes alter the enzymatic and histopathologic profiles. Such alteration can be act bioindicator for environment. The present study been planned observe effect chloride on commercially important fish _Channa punctatus _(body weight 27.04±0.19 g length 16.7±0.20 cm). For...
Background: Forkhead box P3 (FOXP3), a transcription factor is thought to be the master regulator of regulatory T (Treg) cells in maintaining peripheral tolerance and autoimmunity. The number functional capabilities have been reported low several diseases including RA, which affects immune action Treg cells. Proinflammatory cytokines such as tumor necrosis α (TNF-α), are important RA pathogenesis, but influence on poorly understood. Methods: In present study, messenger RNA (mRNA) expressions...